Molecularly imprinted polymers in pharmaceutical sciences. Part I. The principles of formation of molecular imprinting. Applications in drug synthesis and drug delivery techniques

Polimery ◽  
2010 ◽  
Vol 55 (11/12) ◽  
pp. 799-805 ◽  
Author(s):  
PIOTR LULINSKI
The Analyst ◽  
2021 ◽  
Author(s):  
Ghazaleh Jamalipour Soufi ◽  
Siavash Iravani ◽  
Rajender S Varma

Molecularly imprinted polymers (MIPs) have numerous applications in sensing field, the detection/recognition of virus, the structure determination of proteins, drug delivery, artificial/biomimetic antibodies, drug discovery, and cell culturing. There are...


Molecules ◽  
2021 ◽  
Vol 26 (12) ◽  
pp. 3589
Author(s):  
Rui Liu ◽  
Alessandro Poma

Despite the tremendous efforts made in the past decades, severe side/toxic effects and poor bioavailability still represent the main challenges that hinder the clinical translation of drug molecules. This has turned the attention of investigators towards drug delivery vehicles that provide a localized and controlled drug delivery. Molecularly imprinted polymers (MIPs) as novel and versatile drug delivery vehicles have been widely studied in recent years due to the advantages of selective recognition, enhanced drug loading, sustained release, and robustness in harsh conditions. This review highlights the design and development of strategies undertaken for MIPs used as drug delivery vehicles involving different drug delivery mechanisms, such as rate-programmed, stimuli-responsive and active targeting, published during the course of the past five years.


2016 ◽  
Vol 4 (44) ◽  
pp. 7138-7145 ◽  
Author(s):  
Hirobumi Sunayama ◽  
Takeo Ohta ◽  
Atsushi Kuwahara ◽  
Toshifumi Takeuchi

An antibiotic-imprinted cavity with two different fluorescent dyes was prepared by molecular imprinting and subsequent post-imprinting modifications (PIMs), for the readout of a specific binding event as a fluorescence signal.


RSC Advances ◽  
2016 ◽  
Vol 6 (96) ◽  
pp. 94038-94047 ◽  
Author(s):  
Xiao-Lin Wang ◽  
Hong-Fei Yao ◽  
Xiu-Yuan Li ◽  
Xu Wang ◽  
Yan-Ping Huang ◽  
...  

Frontal polymerization was successfully utilized, for the first time, to obtain pH/temperature-sensitive hydrogel-based molecularly imprinted polymers (hydroMIPs).


2006 ◽  
Vol 39 (1) ◽  
pp. 102-106 ◽  
Author(s):  
Ana Rita C. Duarte ◽  
Teresa Casimiro ◽  
Ana Aguiar-Ricardo ◽  
Ana Luísa Simplício ◽  
Catarina M.M. Duarte

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