scholarly journals Diagnostic possibilities for autoimmune thyroiditis using non-invasive determination of intrathyroid iodine concentration in children

2019 ◽  
Vol 45 (1) ◽  
pp. 21-23
Author(s):  
I. A. Vasilevskaya ◽  
I. O. Tomashevsky
Keyword(s):  
Enzyme Immunoassay ◽  
Case History ◽  
Autoimmune Thyroiditis ◽  
Microsomal Fraction ◽  
Iodine Concentration ◽  
Threshold Level ◽  
X Ray ◽  
Non Invasive ◽  
Stable Iodine

Sixty-seven children (55 girls and 12 boys) aged 5-16 years were examined. Autoimmune thyroiditis (AT) was diagnosed in 28 and diffuse nontoxic goiter (DNG) in 39. The diseases were diagnosed on the basis of case history, results of examination and palpation of the thyroid, ultrasonic findings, presence of antibodies to thyroglobulin (in AT) or their absence (in DNG), and the microsomal fraction detected by enzyme immunoassay using Boehringer Mannheim kits. AT diagnosis was confirmed cytomorphologically in all patients. Intrathyroid stable iodine (ISI) was measured by a Russian noninvasive x-ray fluorescent analyzer. ISI concentration was notably decreased in children with autoimmune thyroiditis confirmed by cytomorphological methods: below the threshold level of the method in 46%) cases and 120±10 mcg/g in 54%). This confirms a high informative value of the proposed method in this disease. Measurements of ISI in children with enlarged thyroid helps differentiate the hypertrophic form of AT from DNG: ISI concentration under 200 mcg/g is characteristic of AT, while in DNG the concentration of ISI in Moscow children is 500±40 mcg/g (M±m).

scholarly journals Differential X-Ray Attenuation in MA-XRF Analysis for a Non-invasive Determination of Gilding Thickness

2020 ◽  
Vol 8 ◽  
Author(s):  
Sergio Augusto Barcellos Lins ◽  
Stefano Ridolfi ◽  
Giovanni Ettore Gigante ◽  
Roberto Cesareo ◽  
Monica Albini ◽  
...  
Keyword(s):  
X Ray ◽  
Xrf Analysis ◽  
Non Invasive

X-ray photographic method for determination of stable iodine in tissues

1977 ◽  
Vol 4 (3) ◽  
pp. 264-267
Author(s):  
P. Puumalainen ◽  
P. Suominen
Keyword(s):  
Photographic Method ◽  
X Ray ◽  
Stable Iodine

scholarly journals DIAGNOSTIC TACTICS FOR TRAUMATIC INJURIES OF THE SPLEEN

2020 ◽  
pp. 155-159
Author(s):  
M. M. Belous
Keyword(s):  
Minimally Invasive ◽  
Information Content ◽  
Diagnostic Method ◽  
Diagnostic Methods ◽  
Traumatic Injuries ◽  
X Ray ◽  
Non Invasive ◽  
Examination Methods ◽  
Minimally Invasive Methods

Summary. Purpose. Having based on the determination of the degree of effectiveness and information content of the diagnostic methods for traumatic injuries of the spleen, to analyze the results of the instrumental diagnostic methods to create an algorithm for diagnostic and treatment tactics. Materials and methods: 355 victims were hospitalized with traumatic injuries of the spleen. Of these, physical and laboratory diagnostic methods were used in 100 % of cases, laparoscopy — 245 patients (69 %), laparocentesis — 21 (6 %), laparotomy —- 75 (21 %), ultrasound — 199 (56 %), x-ray — 67 (19 %), CT — 7 (2 %). Research results and discussion.The most informative diagnostic method is laparotomy. Of minimally invasive methods — laparoscopy, and of non-invasive methods — ultrasound. Conclusions. For successful recognition of spleen damage, it is necessary to use complex examination methods, depending on the indication developed for them, that significantly reduces the duration of the diagnostic phase.

scholarly journals Non-Invasive Approaches for the Evaluation of the Functionalization of Melamine Foams with In-Situ Synthesized Silver Nanoparticles

Polymers ◽  
2020 ◽  
Vol 12 (5) ◽  
pp. 996 ◽  
Author(s):  
Suset Barroso-Solares ◽  
Paula Cimavilla-Roman ◽  
Miguel Angel Rodriguez-Perez ◽  
Javier Pinto
Keyword(s):  
Polymeric Nanocomposites ◽  
Free Standing ◽  
X Ray ◽  
Color Changes ◽  
Non Invasive ◽  
Silver Nps ◽  
Promising Solution ◽  
The Stability

The use of polymeric nanocomposites has arisen as a promising solution to take advantage of the properties of nanoparticles (NPs) in diverse applications (e.g., water treatment, catalysis), while overcoming the drawbacks of free-standing nanoparticles (e.g., aggregation or accidental release). In most of the cases, the amount and size of the NPs will affect the stability of the composite as well as their performance. Therefore, a detailed characterization of the NPs present on the nanocomposites, including their quantification, is of vital importance for the optimization of these systems. However, the determination of the NPs load is often carried out by destructive techniques such as TGA or ICP-OES, the development of non-invasive approaches to that aim being necessary. In this work, the amount of silver NPs synthesized directly on the surface of melamine (ME) foams is studied using two non-invasive approaches: colorimetry and X-ray radiography. The obtained results show that the amount of silver NPs can be successfully determined from the luminosity and global color changes of the surface of the foams, as well as from the X-ray attenuance.

scholarly journals Determination of salivary cortisol in donkey stallions

2018 ◽  
Author(s):  
MICAELA SGORBINI ◽  
Francesca Bonelli ◽  
Alessandra Rota ◽  
Christine Aurich ◽  
Natascha Ille ◽  
...  
Keyword(s):  
Enzyme Immunoassay ◽  
Salivary Cortisol ◽  
Circadian Variation ◽  
Cross Reactivity ◽  
Commercial Enzyme ◽  
Standard Curve ◽  
Non Invasive ◽  
Detectable Concentration ◽  
Commercial Enzyme Immunoassay

Salivary cortisol provides information about free plasma cortisol concentration and salivary sampling is a non-invasive well-tolerate procedure. The aim of this study was to validate a commercial enzyme immunoassay for the determination of salivary cortisol in donkeys. Saliva samples were collected in 4 donkey stallions on thirteen non-consecutive days at 8:30 AM to avoid circadian variation. Animals were already accustomed to be handled. Saliva was collected by using a swab inserted at the angle of the lips, placed onto the tongue for 1 min and returned into a polypropylene tube. Tubes were centrifuged and at least 1 ml of saliva was aspirated from each sample and frozen at −20° C until analysis. A commercial enzyme immunoassay kit without extraction was used for determination of cortisol in saliva. Median cortisol concentrations with minimum and maximum value were calculated. Recovery of cortisol standard in donkey saliva was 107.9% and serial dilution of donkey saliva samples with assay buffer resulted in changes in optical density parallel to the standard curve. Cross-reactivity of the antiserum was 10.4% with 11-deoxycortisol, 5.2% with corticosterone, 0.4% with 11-deoxycorticosterone, 0.2% with cortisone and <0.1% with testosterone, progesterone and estradiol. The intra-assay coefficient of variation was 10.7%, the inter-assay variation was 8.0% and the minimal detectable concentration was 0.01 ng/ml. The results of the present study demonstrate the validity of a commercial kit to determine the concentration of cortisol in donkey saliva, as already reported in other species.

scholarly journals Comparison of two methods for the assessment of the levels of autoantibodies to thyroid tissue antigens

1995 ◽  
Vol 41 (5) ◽  
pp. 21-22
Author(s):  
I. Ya. Rudenko ◽  
Yu. L. Skorodok ◽  
V. B. Klimovich
Keyword(s):  
Enzyme Immunoassay ◽  
Adolescent Girls ◽  
Autoimmune Thyroiditis ◽  
Microsomal Fraction ◽  
Solid Phase ◽  
Thyroid Tissue ◽  
Total Extract ◽  
Passive Hemagglutination ◽  
Tissue Antigens ◽  
The Mean

The levels of autoantibodies to total extract of the thyroid were assessed using passive hemagglutination test and of antibodies to thyroglobulin (TG) and thyrocyte microsomal fraction (TMF) by indirect solid-phase enzyme immunoassay in 62 adolescent girls with diffuse enlargement of the thyroid and autoimmune thyroiditis. The efficacies of the two methods were compared. Autoantibodies to thyroid tissue antigens were reliably better detected by enzyme immunoassay. The mean levels of autoantibodies to TG and TMF measured by enzyme immunoassay were reliably increased in patients with autoimmune thyroiditis, whereas in the group of adolescent girls with diffuse enlargement of the thyroid they did not differ from the norm.

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