scholarly journals The role of modern technologies in the management of azoospermia using microdissection TESE in the framework of the ECF-ICSI program. A literature review. Part I.

2012 ◽  
Vol 58 (5) ◽  
pp. 66-74
Author(s):  
I I Vitiazeva ◽  
S V Bogoliubov ◽  
I I Dedov

The present review is focused on the modern methods for the treatment of male infertility related to obstructive and unobstructive azoospermia. The criteria and prognostic factors for obtaining spermatozoa by means of invasive manipulations on the testicles are considered. Special attention is given to the results of investigations into the state of the AZF-region of Y-chromosome and of the studies of patients presenting with Klinefelter's syndrome. The modern classification of testicular biopsies is presented that allows to discriminate between different forms of compromised spermatogenesis.

2021 ◽  
pp. 39-44
Author(s):  
A. V. Ignatovsky

Objective. To present a variant of the modern classification of the processes occurring with lesions of the genitals, to draw specialists’ attention to the peculiarities and variety of causes leading to inflammation of the glans and foreskin, as well as to discuss topical issues of external therapy of balanopostitis.Material and methods. Data from modern studies and clinical guidelines were used in the preparation of the publication.Results. The variety of variants of lesions of the glans and foreskin can be due to a number of reasons and can be either an independent local process or a fragment of dermatosis, where it is possible to be affected in the form of balanoposthitis. Also, when examining and selecting therapy options, it is important to consider the possible role of microorganisms, whose spectrum as a cause of balanoposthitis varies from aerobic and anaerobic, to viral and fungal microflora. Treatment approaches are determined by the etiological factors.Conclusions. Balanoposthitis is a heterogeneous group of nosologies. The choice of treatment is based on the identified cause or empirically when possible. External therapy and hygiene constitute an essential part of treatment. When choosing drugs for topical glucocorticosteroids, preferenceshould be given to drugs with a high therapeutic index and low atrophogenic potential. Dysplastic processes of the penis are associated with human papillomavirus infection, the treatment of which can be both conservative and destructive.


2013 ◽  
Vol 85 (1) ◽  
pp. 1-7
Author(s):  
S. Lanitis ◽  
P. Lazari ◽  
Ch. Kontovounisios ◽  
Ch. Karaliotas ◽  
G. Sgourakis ◽  
...  

Author(s):  
Anastasia O. Razina ◽  
S. D Runenko ◽  
E. E Achkasov

In the literature review there are presented current research trends in the management of obesity and overweight correction. There was noted a multifactoriality ofpathogenesis of obesity and the needfor a multidisciplinary approach to the development of comprehensive programs, including surgical, medical and physiotherapeutic techniques. There were determined priority directions ofpathogenetic treatment process, including the correction of diet, optimization of the motor regimen and the use of aerobic physical loads. There was pointed up the necessity for precise dosing of the load for this category ofpatients, there were presented modern methods of the control of its effective and safe intensity.


Author(s):  
Т.А. Яманди ◽  
Н.Ю. Сафина ◽  
В.Б. Черных ◽  
Л.В. Акуленко

Приводятся данные обследования мужчин с азооспермией и олигозооспермией тяжелой степени, имеющих и не имеющих микроделеции длинного плеча Y-хромосомы, а также результаты биопсии тестикулярной ткани. Отсутствие делеций региона AZF, отсутствие гипоплазии яичек, а также нормальные показатели ФСГ, ЛГ и ингибина В являются прогностически благоприятными критериями в отношении успешности получения сперматозоидов при биопсии ткани яичка для проведения экстракорпорального оплодотворения (ЭКО). The article presents the results of a survey of men with azoospermia and severe oligozoospermia, with and without microdeletion of the long arm of the Y chromosome, as well as the results of a testicular biopsy. The absence of deletions of the AZF region, the absence of testicular hypoplasia, as well as normal levels of FSH, LH and inhibin B are prognostically favorable criteria for the success of obtaining spermatozoa with a biopsy of testicular tissue for in vitro fertilization (IVF).


2001 ◽  
Vol 3 (3) ◽  
pp. 1-16 ◽  
Author(s):  
Nabeel A. Affara

It was suggested by Ronald Fisher in 1931 that genes that benefit the male (including those required for spermatogenesis) would accumulate on the Y chromosome. Following the discovery that microdeletions of the Y chromosome were associated with diverse spermatogenic phenotypes, at least three intervals that contain one or more genes controlling male germ-cell differentiation have been identified in humans. These intervals, named AZFa, AZFb and AZFc, have been mapped, cloned and examined in detail for the presence of functional genes. In this review, I have discussed the genes that map to the AZF intervals and the evidence indicating which ones are the most likely candidates underlying Y-linked male infertility. In addition, I have considered the analysis of key intervals on the mouse Y chromosome, where it provides comparative data supporting the role of a candidate gene in an infertility phenotype.


Author(s):  
Никита Николаевич Равочкин

В последние годы целый ряд исследователей соглашается с тем, что идеи наряду с материальными факторами способствуют построению каких-либо объяснений социальных преобразований. В то же время, существует устойчивое и резко противоположное мнение, что идеи сами по себе являются исключительно теоретически перегруженными конструктами, которые в принципе мало что значат. Важным замечанием представляется инструментальная роль идей в преодолении ограниченной рациальности различных акторов, без обращения к которым они вряд ли достигли бы желаемых прагматических эффектов совершенных действий. Настоящая статья посвящена прикладному значению идей, которые воплощаются в целые технологии управления социальными процессами. Обоснована значимость интеллектуальных ресурсов в контексте Постсовременности. Показано, что представляют собой современные технологии социального управления. Выявлено место идеальных элементов в структуре управления процессами. В логике авторского подхода рассмотрены примеры дистрибуции идей от генезиса до их практической реализации в различных сферах общественной жизни. Уточнена инновационность идей, к которым перманентно обращаются акторы. Актуализировано состояние манипулятивных практик, к которым вынуждены прибегать властные субъекты. Приведена классификация идей, задающих концептуальные основания альтернативных утилитарных действий. В заключение обобщаются основные выводы и подводятся итоги исследования. In recent years, a number of researchers have agreed that ideas, along with material factors, contribute to the construction of any explanations for social transformations. At the same time, there is a stable and sharply opposite opinion that ideas in themselves are exclusively theoretically overloaded constructs that, in principle, mean little. An important remark is the instrumental role of ideas in overcoming the limited rationality of various actors, without recourse to which they would hardly have achieved the desired pragmatic effects of committed actions. This article is devoted to the applied meaning of ideas that are embodied in whole technologies for managing social processes. The importance of intellectual resources in the context of Postmodernity has been substantiated. It is shown what modern technologies of social management are. Revealed the place of ideal elements in the structure of process management. In the logic of the author's approach, examples of the distribution of ideas from genesis to their practical implementation in various spheres of public life are considered. Clarified the innovativeness of ideas to which actors are permanently referring. The state of manipulative practices that powerful subjects are forced to resort to has been updated. A classification of ideas defining the conceptual foundations of alternative utilitarian actions is given. In conclusion, the main findings are summarized and the results of the study are summed up.


2020 ◽  
Vol 75 (3) ◽  
pp. 13-19
Author(s):  
V.A. Gol′brah ◽  
◽  
S.S. Maskin ◽  
V.V. Matyukhin ◽  
◽  
...  

The enchantment of numbers of surgical interventions and the widespread adoption of modern technologies, lead to a parallel increase in technological errors and morbidity in recent years. This article analyzes such section of surgery as «medical errors», provides a modern classification of medical errors and complications according to foreign and Russian authors. The article contains information about definition, legal foundations and principles for the prevention of unexpected consequences of surgical interventions


Andrologia ◽  
2021 ◽  
Author(s):  
Nemanja Vučić ◽  
Nevena Kotarac ◽  
Suzana Matijašević ◽  
Lana Radenković ◽  
Ivan Vuković ◽  
...  

2016 ◽  
Vol 42 (9) ◽  
pp. S133
Author(s):  
S. Lanitis ◽  
P. Zafeiriadou ◽  
N. Arkadopoulos ◽  
S. Peristeraki ◽  
A. Kouloura ◽  
...  

Sign in / Sign up

Export Citation Format

Share Document