scholarly journals APLICACIÓN DE COLORACIONES ESPECIALES EN EL DIAGNÓSTICO HISTOPATOLÓGICO: TINCIÓN TRICRÓMICA DE MASSON

2021 ◽  
Vol 19 (suplemento) ◽  
Author(s):  
N RN Cruz
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Bovine Liver ◽  
Tumor Stroma ◽  
Staining Technique ◽  
Accurate Information ◽  
Histopathological Diagnosis ◽  
Rabbit Lung ◽  
Staining Protocol

Masson's trichrome (MT) is a three-color staining protocol used in histology. MT allows to show and quantify changes such as tissue repair (healing) and collagen deposition. Also, it can be used to quantify blood vessels, in epithelial dysplasia and squamous cell carcinoma. The objective of this work is to describe the MT staining technique and to exemplify some applications of this technique in routine veterinary histopathological diagnosis. Archived histologic sections were selected from the records of the histopathology laboratory. Tissues were selected in base on theirs structures and lesions that could be evaluated with MT: a rabbit lung with a chronic suppurative bronchopneumonia; a bovine liver with lesions of Echium plantagineum poisoning; and a bovine eyelid with a squamous cell carcinoma. The TM was able to show fibroplasia in the pulmonary interstitium and confirm the presence of a chronic respiratory process, and clearly revealed an abundant fibrovascular tumor stroma, with profuse connective tissue and neovascularization between the tumor cells in deep dermis. In the liver, extensive and marked fibroplasia was confirmed. MT represents a complementary coloration to routine hematoxylin and eosin stain (H&E) and provides accurate information from several pathological processes, mainly those related to fibrovascular proliferation and scarring.

scholarly journals Cigarette Smoke Induces Metabolic Reprogramming of the Tumor Stroma in Head and Neck Squamous Cell Carcinoma

2019 ◽  
Vol 17 (9) ◽  
pp. 1893-1909 ◽  
Author(s):  
Marina Domingo-Vidal ◽  
Diana Whitaker-Menezes ◽  
Cristina Martos-Rus ◽  
Patrick Tassone ◽  
Christopher M. Snyder ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Head And Neck ◽  
Cigarette Smoke ◽  
Squamous Cell ◽  
Tumor Stroma ◽  
Metabolic Reprogramming ◽  
Neck Squamous Cell Carcinoma

scholarly journals Squamous cell carcinoma mimicking a wart

2021 ◽  
Vol 12 (4) ◽  
pp. 471-472
Author(s):  
Aida Oulehri ◽  
Sara Elloudi ◽  
Hanane Baybay
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Soft Tissues ◽  
Verrucous Carcinoma ◽  
Previous History ◽  
Histopathological Diagnosis ◽  
Low Grade ◽  
Complete Surgical Excision ◽  
Safety Margins

Sir, Cutaneous squamous cell carcinoma, a malignant proliferation of the cutaneous epithelium, represents the second most common non-melanoma skin cancer after basal cell carcinoma [1]. Verrucous carcinoma (VC) is a rare, low-grade, well-differentiated squamous cell carcinoma most commonly seen in the mucosa, infrequently reported to occur in the skin, where it is a slow-growing and locally aggressive tumor. It is not uncommon for cutaneous verrucous carcinomas to be mistaken for the more frequent wart (verruca vulgaris) and treated accordingly [2]. The etiopathogenesis of VC is not completely known. One theory mentions the human papillomavirus (HPV) infection; with plantar lesions, the types involved are reported to be 16 and 11 [3]. Histopathological diagnosis is difficult and needs one or more broad and in-depth biopsies. Morbidity results from the local destruction of the skin and soft tissues and, occasionally, from a perineural, muscular, and even bony invasion. Metastasis to regional lymphatic ganglia is rare, found in 5% of cases [4]. VC bears a high risk of local relapse. No matter the treatment employed, the rate of recurrence varies from 30% to 50% and usually is not the result of incomplete surgical interventions. The treatment of choice is complete surgical excision with safety margins [5]. A forty-year-old female patient with no previous history presented herself with a hyperkeratotic lesion on the right foot persistent for two years, which she had been manipulating routinely, which had progressively been increasing in size for the previous year, and which, for the previous three months, had become painful and bleeding. An examination revealed a hyperkeratotic plaque with a hyperpigmented border, hard on palpation, adherent to the deep plane, and with an eroded surface (Fig. 1). Dermoscopy was able to find a papillomatous appearance surrounded by dotted vessels (Fig. 2). This dermoscopic aspect typical of vulgar warts was confusing. Indeed, dermoscopy of the foot wart shows red or black dots in the center of papillomatous structures, which are thrombosed vessels supplying the wart; hence the importance, in our opinion, of the clinical and pathological correlation. For this reason, we performed a skin biopsy; an anatomopathological study found a squamous cell carcinoma of the verrucous type.

scholarly journals SCALED CELL CARCINOMA TYPE VERRUCOUS INFILTRATED – CASE STUDY

2019 ◽  
Vol 7 (4) ◽  
pp. 11-16
Author(s):  
Dr. Xavier Antonio Chan Gómez ◽  
Dr. Jorge Daher Nader ◽  
Bella Vallejo López
Keyword(s):  
Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Histopathological Diagnosis ◽  
Early Complications ◽  
Early Health ◽  
Vulvar Tumor ◽  
Present Case Study

Disorders in patients who develop squamous cell carcinoma can lead to severe conditions. The present case study evidences the advance of this pathology in a patient who goes to the medical services when the problem has advanced. Objective- To describe the case of a patient who underwent surgery to remove a tumor from the vulvar region to prevent it from triggering in severe states. Method - Surgery of a vulvar tumor, performed on a female patient of 62 years. Result- Squamous cell carcinoma, infiltrative verrucous type, with dimensions of 7x6 cm, with an invasion depth of 2.7 mm in the central region    Conclusion- This type of pathology should not be allowed to worsen when it occurs, as it deteriorates the quality of life of patients over the years. If it is detected and treated early, complications can be avoided. In the present case, the histopathological diagnosis was epidermoid carcinoma. It is expected that the information collected will be useful to professionals and that it contributes as an alert to detect early health problems in patients.

Procedures and pitfalls in incisional biopsies of oral squamous cell carcinoma with respect to histopathological diagnosis

2020 ◽  
Vol 66 (12) ◽  
pp. 101035
Author(s):  
Roopa S. Rao ◽  
Kasimsetty Ramakantha Chatura ◽  
Sowmya SV ◽  
Kavitha Prasad ◽  
Surendra Lakshminarayana ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Histopathological Diagnosis

A Systems Biology Approach Identifies Effective Tumor–Stroma Common Targets for Oral Squamous Cell Carcinoma

2014 ◽  
Vol 74 (8) ◽  
pp. 2306-2315 ◽  
Author(s):  
Wenxia Meng ◽  
Yun Wu ◽  
Xin He ◽  
Chuanxia Liu ◽  
Qinghong Gao ◽  
...  
Keyword(s):  
Squamous Cell Carcinoma ◽  
Systems Biology ◽  
Oral Squamous Cell Carcinoma ◽  
Cell Carcinoma ◽  
Squamous Cell ◽  
Tumor Stroma
Sign in / Sign up

Export Citation Format

Share Document