Magnetic nanoparticles adapted for specific biomedical applications

Author(s):  
Silvio Dutz ◽  
Robert Müller ◽  
Dietmar Eberbeck ◽  
Ingrid Hilger ◽  
Matthias Zeisberger

AbstractMagnetic nanoparticles (MNPs) are used in different biomedical applications, whereby each application requires specific particle properties. To fulfill these requirements, particle properties have to be optimized by means of variation of crystal structure, particle size, and size distribution. To this aim, improved aqueous precipitation procedures for magnetic iron oxide nanoparticle synthesis were developed. One procedure focused on the cyclic growth of MNPs without nucleation of new particle cores during precipitation. The second novel particle type are magnetic multicore nanoparticles, which consist of single cores of approximately 10 nm forming dense clusters in the size range from 40 to 80 nm. Their highest potential features these multicore particles in hyperthermia application. In our

2021 ◽  
Vol 64 (2) ◽  
pp. 202-210
Author(s):  
Muhammad Isa Khan ◽  
Aliza Zahoor ◽  
Tahir Iqbal ◽  
Abdul Majid ◽  
Mohsin Ijaz

  Recently, different researchers find nanoparticles as an auspicious alternative to antibacterial agents due to their antibacterial behaviour. This antibacterial behaviour contributes in many biomedical applications including; tissue engineering, drug and gene delivery and, imaging. Furthermore, iron oxide nanoparticle gains much importance due to their magnetic characteristics and wide range of application. Iron oxide nanoparticle (IONPs) have exhibits great potential against bacteria. During the past decade, various routes were developed to synthesize iron oxide nanoparticle with suitable size and composition. This article reviews the recent iron oxide nanoparticle obtained by green synthesis with a focus on their response to antibacterial activities. The iron nanoparticles synthesized by green synthesis method has accumulated a vital attention over the last couple of years due to their unique characteristic as it makes sure environmental friendly, nontoxic and safe reagents.


2009 ◽  
Vol 16 (10) ◽  
pp. 1278-1294 ◽  
Author(s):  
J. Xie ◽  
J. Huang ◽  
X. Li ◽  
S. Sun ◽  
X. Chen

RSC Advances ◽  
2019 ◽  
Vol 9 (67) ◽  
pp. 39381-39393 ◽  
Author(s):  
Jiacheng Yu ◽  
Tongwei Zhang ◽  
Huangtao Xu ◽  
Xiaoli Dong ◽  
Yao Cai ◽  
...  

A novel thermostable ferritin from Pyrococcus yayanosii CH1 directs the synthesis of thermostable magnetoferritins (M-PcFn5000) in one step.


2019 ◽  
Vol 6 (3) ◽  
pp. 75 ◽  
Author(s):  
Laura M. Sanchez ◽  
Vera A. Alvarez

The study of the noble metal magnetic hybrid nanoparticles is a really promising topic from both the scientific and the technological points of views, with applications in several fields. Iron oxide materials which are hybridized with noble metal nanoparticles (NPs) have attracted increasing interest among researchers because of their cooperative effects on combined magnetic, electronic, photonic, and catalytic activities. This review article contains a summary of magnetic noble metal/iron oxide nanoparticle systems potentially useful in practical biomedical applications. Among the applications, engineered devices for both medical diagnosis and treatments were considered. The preparation to produce different structures, as blends or core-shell structures, of several nanometric systems was also considered. Several characterization techniques available to describe the structure, morphology and different kinds of properties of hybrid nanoparticles are also included in this review.


Soft Matter ◽  
2020 ◽  
Vol 16 (45) ◽  
pp. 10244-10251
Author(s):  
Samuel D. Oberdick ◽  
Stephen E. Russek ◽  
Megan E. Poorman ◽  
Gary Zabow

We show that MRI can be used to characterize dynamics of magnetic nanoparticle growth during the synthesis of magnetically responsive polymer gels.


2018 ◽  
Vol 3 (2) ◽  
pp. 64 ◽  
Author(s):  
Aneela Hameed ◽  
Hafiza Mehvish Mushtaq ◽  
Majid Hussain

<p>Nanoparticles are smaller than 100nm. Size of particle depends upon the method that is used for synthesis of nanoparticles. Magnetic nanoparticles consist of iron, cobalt and nickel and their chemical compounds. Their safety or toxicity is major concern for use in food. Magnetite, hematite and meghemite are types of magnetic nanoparticles. Magnetite (Fe3O4) common among the magnetic iron oxide nanoparticle that is used in food industry. Magnetite is getting popular due to its super paramagnetic properties and lack of toxicity to humans. Different methods are used to synthesize magnetic nanoparticles. Upon contact with air these particles loses magnetism and mono-dispersibility. To overcome this problem these nanoparticles are coated with natural or synthetic polymers, metals, organic and inorganic substances to create stable and hydrophilic nanostructures. Due to easy separation with magnet these magnetic nanoparticles are used as an affinity probe to remove bacteria from different food samples and have food related applications e.g, protein purification, enzyme immobilization and food analysis. These magnetic nanoparticles also used for removal of heavy metals and used in medical field.</p>


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