scholarly journals Homocysteine, type 2 diabetes mellitus, and cognitive performance: The Maine-Syracuse Study

Author(s):  
Michael A. Robbins ◽  
Merrill F. Elias ◽  
Marc M. Budge ◽  
Suzanne L. Brennan ◽  
Penelope K. Elias

AbstractType 2 diabetes mellitus and higher total plasma homocysteine concentrations are each associated with an increased incidence of cardiovascular disease and with diminished cognitive performance. Relations between homocysteine concentrations and cardiovascular disease incidence are stronger in the presence of type 2 diabetes mellitus. Therefore, we hypothesized that relations between homocysteine concentrations and cognitive performance would be stronger in the presence of type 2 diabetes. We related homocysteine concentrations and cognitive performance on the Mini-Mental State Examination in 817 dementia- and stroke-free participants of the Maine-Syracuse Study, 90 of whom were classified with type 2 diabetes mellitus. Regardless of statistical adjustment for age, sex, gender, vitamin co-factors (folate, vitamin B

2009 ◽  
Vol 103 (10) ◽  
pp. 1364-1367 ◽  
Author(s):  
José A. Gimeno-Orna ◽  
Eduardo Faure-Nogueras ◽  
Francisco J. Castro-Alonso ◽  
Beatriz Boned-Juliani

2005 ◽  
Vol 51 (1) ◽  
pp. 31-36 ◽  
Author(s):  
Alena Šmahelová ◽  
Radek Hyšpler ◽  
Tomáš Haas ◽  
Alena Tichá ◽  
Vladimír Bláha ◽  
...  

2012 ◽  
Vol 2012 ◽  
pp. 1-6 ◽  
Author(s):  
Melissa S. Burroughs Peña ◽  
Dhaval Patel ◽  
Delfin Rodríguez Leyva ◽  
Bobby V. Khan ◽  
Laurence Sperling

Cardiovascular disease is the leading cause of mortality in Cuba. Lifestyle risk factors for coronary heart disease (CHD) in Cubans have not been compared to risk factors in Cuban Americans. Articles spanning the last 20 years were reviewed. The data on Cuban Americans are largely based on the Hispanic Health and Nutrition Examination Survey (HHANES), 1982–1984, while more recent data on epidemiological trends in Cuba are available. The prevalence of obesity and type 2 diabetes mellitus remains greater in Cuban Americans than in Cubans. However, dietary preferences, low physical activity, and tobacco use are contributing to the rising rates of obesity, type 2 diabetes mellitus, and CHD in Cuba, putting Cubans at increased cardiovascular risk. Comprehensive national strategies for cardiovascular prevention that address these modifiable lifestyle risk factors are necessary to address the increasing threat to public health in Cuba.


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