New creatinine sensor for point-of-care testing of creatinine meets the National Kidney Disease Education Program guidelines

Author(s):  
Anne Skurup ◽  
Tina Kristensen ◽  
Gitte Wennecke
Author(s):  
Anne K. Shephard ◽  
Mark D.S. Shephard ◽  
Heather J. Halls ◽  
Olivia Corso ◽  
Timothy H. Mathew

Author(s):  
Nuntanuj Vutthikraivit ◽  
Patcharakorn Kiatamornrak ◽  
Chatikorn Boonkrai ◽  
Trairak Pisitkun ◽  
Kittinan Komolpis ◽  
...  

2021 ◽  
pp. 193229682110545
Author(s):  
Bernd Schultes ◽  
Susanne Emmerich ◽  
Andreas D. Kistler ◽  
Badreddine Mecheri ◽  
Oliver Schnell ◽  
...  

Background: For the diagnosis of diabetic kidney disease (DKD), quantitative albuminuria measurement using the albumin-to-creatinine ratio (ACR) is recommended according to various guidelines. It can be measured either in specialized laboratories or using ACR point-of-care testing (POCT). This observational study aims at evaluating the effect of ACR POCT utilization on the DKD diagnosis and treatment management for glycemic control and blood pressure. Method: Data of 717 patients with diabetes (type 1 diabetes: n = 236; type 2 diabetes: n = 463; other diabetes forms: n = 18) were assessed in three centers. The impact of ACR POCT on DKD diagnosis and treatment management for glycemic control and blood pressure was assessed using a case report form. The assessment of ACR POCT utilization purpose and relevance for physicians was documented using a questionnaire. Results: Of all participants (n = 717), 39.1% had a confirmed/suspected DKD diagnosis. Hereof, 8.6% were newly diagnosed with DKD, and 9.9% were suspected with DKD based on the actual ACR POCT values. Within the group of patients with confirmed/suspected DKD (n = 280), treatment modification was performed in 46.1% of participants. A drug initiation with GLP-1 receptor agonists or SGLT2 inhibitors was performed in 11.1% or 8.9% of patients with confirmed/suspected DKD, respectively. Regarding the utilization purposes of ACR POCT, 100% of the physicians (n = 8) indicated using it to examine patients with diabetes with or without hypertension; 75% considered it very important for patients with diabetes. Conclusions: The implementation of ACR POCT may positively affect DKD diagnosis and subsequently allow better management of patients with diabetes.


2015 ◽  
Vol 65 (640) ◽  
pp. 608-608 ◽  
Author(s):  
Oghenekome Gbinigie ◽  
Christopher P Price ◽  
Carl Heneghan ◽  
Ann Van den Bruel ◽  
Annette Plüddemann

2020 ◽  
Vol 27 ◽  
Author(s):  
Yi Zhang

: Point-of-care (POC) testing decentralizes the diagnostic tests to the sites near the patient. Many POC tests rely microfluidic platforms for sample-to-answer analysis. Compared to other microfluidic systems, magnetic digital microfluidics demonstrate compelling advantages for POC diagnostics. In this review, we have examined the capability of magnetic digital microfluidics-based POC diagnostic platforms. More importantly, we have categorized POC settings into three classes based on “where is the point”, “who to care” and “how to test”, and evaluated the suitability of magnetic digital microfluidics in various POC settings. Furthermore, we have addressed other technical issues associated with POC testing such as controlled environment, sample-system interface, system integration and information connectivity. We hope this review would provide a guideline for the future development of magnetic digital microfluidics-based platforms for POC testing.


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