Peptic esophageal stricture in an adolescent with Barrett’s esophagus

2016 ◽  
Vol 29 (5) ◽  
Author(s):  
Sandeep Lamoria ◽  
Arka De ◽  
Somya Agarwal ◽  
Brinder Mohan Singh Lamba ◽  
Vishal Sharma
Keyword(s):  
Barrett’S Esophagus ◽  
Barrett's Esophagus ◽  
Esophageal Stricture ◽  
Pediatric Population ◽  
Barium Meal ◽  
Cardiac Mucosa ◽  
Esophageal Strictures ◽  
History Of ◽  
Stratified Squamous Epithelium ◽  
Progressive Dysphagia

Abstract Barrett’s esophagus (BE) is characterized by the replacement of distal esophageal stratified squamous epithelium by columnar epithelium. It is rare in children and the risk factors may include mental retardation, cerebral palsy, esophageal atresia, etc. Apart from corrosive ingestion, peptic stricture is the other leading cause of esophageal strictures in children. However, BE has not been well characterized in the pediatric population and in children presenting with esophageal strictures. A 16-year-old Indian boy presented with a history of gradually progressive dysphagia to solids (but not liquids) for 12 years along with heartburn and poor weight gain. Physical examination and routine blood investigations were unremarkable. Previously performed barium meal studies were suggestive of stricture in the mid and lower esophagus. Upper gastrointestinal (GI) endoscopy revealed a non-negotiable stricture with circumferential ulceration at 26 cm. The stricture was traversed using an ultrathin scope and the distal mucosa was found to be columnar. Biopsies revealed cardiac mucosa. The patient was treated with proton pump inhibitors (PPI) and four series of segmental dilatations with Savary Gilliard esophageal dilators. Peptic strictures occurring in the mid-upper esophagus should raise concerns about BE or malignancy. Here, we report a case of peptic esophageal stricture in a child without neurodevelopmental or trachea-esophageal abnormalities.

Histopathological Spectrum of Premalignant and Malignant Lesions of Esophagus in the Population of Karachi

2020 ◽  
Author(s):  
Asma Shabbir
Keyword(s):  
Barrett’S Esophagus ◽  
Barrett's Esophagus ◽  
Single Case ◽  
Malignant Neoplasms ◽  
Reference Laboratory ◽  
Histologic Pattern ◽  
Male Preponderance ◽  
Stratified Squamous Epithelium ◽  
Grade Ii ◽  
Diagnostic Research

Background: Squamous cell carcinoma (SCC) and adenocarcinoma are the most common esophageal cancers. Barrett’s esophagus is the change of esophageal stratified squamous epithelium to columnar cells which if remain undiagnosed follows the dysplasia – carcinoma sequence. The last two decades show a change in the histologic pattern of esophageal carcinoma. Adenocarcinoma is at majority rate than SCC in the West, however, in Asia, SCC is still the commonest cancer of esophagus. In this study, we aim to define a spectrum of premalignant and malignant neoplasms of esophagus in our region. Methods: This study was done at Dow Diagnostic Research and Reference Laboratory (DDRRL). All the cases of preneoplastic and neoplastic lesions of esophagus received during the period of 7 years (2009-2015) were reviewed. The data obtained were subjected to descriptive statistical analysis using SPSS version 21. Results: Out of 94 premalignant cases, 70 (74.5%) were diagnosed as Barrett’s esophagus, 23 (24.5%) as dysplasia and 1 (1.1%) as adenoma. From the total of 450 malignant cases, 395 (87.7%) were SCC, 54 (12%) were adenocarcinoma and a single case of leiomyoma was diagnosed. Grade II SCC was found to be most the common lesion. Conclusion: Barrett’s esophagus was more than dysplasia and showed male preponderance. SCC was the predominant esophageal cancer, which is similar to the other studies in our country. SCC was found more common in females than males and vice versa for adenocarcinoma. Majority of all the cases belonged to 41-60 years of age group.

ID: 3522314 EXCESSIVE BIOPSIES IN PATIENTS WITH AN IRREGULAR Z LINE AND NO HISTORY OF BARRETT’S ESOPHAGUS

2021 ◽  
Vol 93 (6) ◽  
pp. AB306
Author(s):  
Thomas J. Kaminsky ◽  
Keegan Colletier ◽  
John C. Fang ◽  
Kathryn R. Byrne ◽  
Andrew J. Gawron
Keyword(s):  
Barrett’S Esophagus ◽  
Barrett's Esophagus ◽  
History Of

scholarly journals Barrett’s Esophagus Without Esophageal Stricture Does Not Increase the Rate of Failure of Nissen Fundoplication

2003 ◽  
Vol 237 (4) ◽  
pp. 488-493 ◽  
Author(s):  
Pascual Parrilla ◽  
Luisa F. Martínez de Haro ◽  
Angeles Ortiz ◽  
Vicente Munitiz ◽  
Andres Serrano ◽  
...  
Keyword(s):  
Barrett’S Esophagus ◽  
Barrett's Esophagus ◽  
Esophageal Stricture ◽  
Nissen Fundoplication ◽  
Rate Of Failure

Mo1740 - Family History of Colorectal Cancer and Risk for Barrett's Esophagus

2018 ◽  
Vol 154 (6) ◽  
pp. S-791
Author(s):  
Anna Tavakkoli ◽  
Erika Koeppe ◽  
Peter Ulintz ◽  
John M. Inadomi ◽  
Hal Morgenstern ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Family History ◽  
Barrett’S Esophagus ◽  
Barrett's Esophagus ◽  
History Of

scholarly journals Standard versus simplified radiofrequency ablation protocol for Barrett’s esophagus: comparative analysis of the whole treatment pathway

2020 ◽  
Vol 08 (02) ◽  
pp. E189-E195 ◽  
Author(s):  
Wei Keith Tan ◽  
Krish Ragunath ◽  
Jonathan R. White ◽  
Jose Santiago ◽  
Jacobo Ortiz Fernandez-Sordo ◽  
...  
Keyword(s):  
Comparative Analysis ◽  
Radiofrequency Ablation ◽  
Complete Remission ◽  
Barrett’S Esophagus ◽  
Barrett's Esophagus ◽  
Median Number ◽  
Standard Protocol ◽  
Efficacy And Safety ◽  
Treatment Pathway ◽  
Esophageal Strictures

Abstract Background and study aims The standard radiofrequency ablation (RFA) protocol for Barrett’s esophagus (BE) encompasses an intermediary cleaning phase between two ablation sessions. A simplified protocol omitting the cleaning phase is less labor-intensive but equally effective in studies based on single ablation procedures. The aim of this study was to compare efficacy and safety of the standard and simplified RFA protocols for the whole treatment pathway for BE, including both circumferential and focal devices. Patients and methods We performed a retrospective analysis of prospectively collected data on patients receiving RFA between January 2007 and August 2017 at two institutions. Outcomes assessed were: 1) complete remission of dysplasia (CR-D) and intestinal metaplasia (CR-IM) at 18 months; and 2) rate of esophageal strictures. Results One hundred forty-five patients were included of whom 73 patients received the standard and 72 patients received the simplified protocol. CR-D was achieved in 94.5 % and 95.8 % of patients receiving the standard and simplified protocol, respectively (P = 0.71). CR-IM was achieved in 84.9 % and 77.8 % of patients treated with the standard and simplified protocol, respectively (P = 0.27). Strictures were significantly more common among patients who received the simplified protocol (12.5 %) compared to the standard protocol (1.4 %; P = 0.008). The median number of esophageal dilations was one. Conclusion The simplified RFA protocol is as effective as the standard protocol in eradicating BE but carries a higher risk of strictures. This needs to be taken into account, particularly in patients with higher pretreatment risk of strictures, such as those with esophageal narrowing from previous endoscopic mucosal resection (EMR).

scholarly journals Prevalence and Natural History of Barrett’s Esophagus in Lung Transplant: A Single-Center Experience

2019 ◽  
Vol 107 (4) ◽  
pp. 1017-1023 ◽  
Author(s):  
Sreeja Biswas Roy ◽  
Paul Banks ◽  
Matthew Kunz ◽  
Taylor R. Ipsen ◽  
Takahiro Masuda ◽  
...  
Keyword(s):  
Natural History ◽  
Barrett’S Esophagus ◽  
Barrett's Esophagus ◽  
Lung Transplant ◽  
Single Center ◽  
Single Center Experience ◽  
History Of

scholarly journals Incidence of Dysplasia in Patients with Barrett’s Esophagus

QJM ◽  
2020 ◽  
Vol 113 (Supplement_1) ◽  
Author(s):  
H A Elakkad ◽  
A M M Elhefny ◽  
M A Alsayed ◽  
K W Shawky
Keyword(s):  
Risk Factors ◽  
Barrett’S Esophagus ◽  
Esophageal Adenocarcinoma ◽  
Barrett's Esophagus ◽  
Inclusion Criteria ◽  
Upper Gi ◽  
The Past ◽  
History Of ◽  
Upper Gi Endoscopy ◽  
Malignant Condition

Abstract Background Barrett’s esophagus is a condition which predisposes towards development of dysplasia and finally towards esophageal adenocarcinoma, a highly lethal tumour which has been increasing in incidence over the past three decades. Although BE is the single best identified risk factor for the development of esophageal adenocarcinoma, yet the overwhelming majority of Barrett’s patients will never develop this cancer. Objective To evaluate the incidence of dysplasia in patients with BE regarding risk factors such as gender, smoking, obesity, patient’s age, duration of reflux, treatment received, associated disease as DM and esophageal histopathology. Patients and Methods The study was conducted on 30 patients previously diagnosed with BE. The patients were selected according to some inclusion criteria such as being diagnosed by upper GI endoscopy and a biopsy was taken. Patients with history of previous anti-reflux surgery were excluded. Results A strong correlation was found between the incidence of dysplasia and male gender, mean age 58.17 years, smoking, DM, hiatus hernia and esophagitis. Conclusion As the incidence of dysplasia and esophageal adenocarcinoma continues to rise at an alarming rate, widespread endoscopic surveillance of Barrett’s esophagus patients is performed in order to detect any abnormality at an earlier and potentially curable stage. In addition to highlighting the risk factors that aggravates this pre-malignant condition.

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