scholarly journals Transient benign hyperphosphatasemia due to COVID-19: the first case report

2020 ◽  
Vol 0 (0) ◽  
Author(s):  
Tugba Erat ◽  
Müge Atar ◽  
Tugba Kontbay
Keyword(s):  
Polymerase Chain Reaction ◽  
Alkaline Phosphatase ◽  
Case Report ◽  
Rt Pcr ◽  
Chain Reaction ◽  
Benign Condition ◽  
Case Presentation ◽  
Normal Ranges ◽  
First Case ◽  
Polymerase Chain

AbstractObjectivesCoronavirus disease (COVID-19) rapidly spread worldwide in a few months and was declared as a worldwide pandemic by WHO in March 2020. Transient benign hyperphosphatasemia (THI) is a benign condition associated with marked elevation of alkaline phosphatase (ALP) without any other kidney, bone, and liver pathologies.Case presentationHerein, we report a previously healthy 16-month-old female patient who developed a secondary transient benign hyperphosphatasemia associated with SARS-CoV-2. Patient whole family’s SARS-CoV-2 real-time reverse transcription-polymerase chain reaction (RT-PCR) results were positive. Since THI is a diagnosis of exclusion, other reasons that may cause ALP elevation should be ruled out. ALP activity decreased and turned to normal ranges within the following month. THI has been reported to be in association with various conditions. Its relationship with many viruses has been reported previously.ConclusionsIf ALP elevation is detected in patients with COVID 19 due to the increasing number of infections, THI should be considered if there is no other accompanying pathology.

scholarly journals Multiple Negative of RT-PCR Testing of COVID-19 Pneumonia: A Case Report

2020 ◽  
Author(s):  
HuiLi ◽  
Junton Feng ◽  
Lamei Chen ◽  
Yinhao Wu ◽  
Yan Su ◽  
...  
Keyword(s):  
Polymerase Chain Reaction ◽  
Case Report ◽  
Reverse Transcriptase ◽  
Clinical Manifestation ◽  
Lymphocyte Count ◽  
Rt Pcr ◽  
Chain Reaction ◽  
Case Presentation ◽  
Polymerase Chain ◽  
Novel Coronavirus

Abstract Background: Since the 2019 novel coronavirus outbreak in Wuhan, Hubei Province, China in 2019, there have been a few reports of multiple negative of RT-PCR tests in patients infected by 2019 novel coronavirus.Case presentation: The patient was a 64-year-old man with fever. His son returned from Hubei 17 days before the patient had fever. Ancillary examinations indicated a decreased lymphocyte count and ground-glass opacities in lung. However, the first five reverse transcriptase polymerase chain reaction tests of 2019 novel coronavirus were negative until the sixth turned to positive.Conclusion: when epidemiological history, clinical manifestation and imaging are highly suggestive of COVID-19 Pneumonia, we should repeat reverse transcriptase polymerase chain reaction tests and treat patients in isolation.

scholarly journals Case Report: Acute Intracardiac Thrombosis in Children With Coronavirus Disease 2019 (COVID-19)

2021 ◽  
Vol 9 ◽  
Author(s):  
Hamid Bigdelian ◽  
Mohsen Sedighi ◽  
Mohammad Reza Sabri ◽  
Bahar Dehghan ◽  
Chehreh Mahdavi ◽  
...  
Keyword(s):  
Polymerase Chain Reaction ◽  
Cardiac Surgery ◽  
Case Report ◽  
Case Series ◽  
Rt Pcr ◽  
Chain Reaction ◽  
Inflammatory State ◽  
Polymerase Chain ◽  
Underlying Mechanisms ◽  
Intracardiac Thrombosis

We herein describe a case series of children with SARS-CoV-2 infection (COVID-19) complicated with acute intracardiac thrombosis. The diagnosis of COVID-19 was confirmed through the reverse transcription-polymerase chain reaction (RT-PCR). Transthoracic echocardiography of patients revealed large intracardiac mobile masses resected successfully via cardiac surgery. The underlying mechanisms of this thrombus in the COVID-19 infection may be attributed to the hypercoagulation and inflammatory state of the disease incurred by the SARS-CoV-2 virus.

scholarly journals Chilblains-Like Lesions as a Presenting Manifestation of COVID-19

2020 ◽  
Vol 4 (5) ◽  
pp. 440-442
Author(s):  
Victoria Comeau ◽  
Marcus Goodman ◽  
Carmen Julian ◽  
Francesca M Ceci
Keyword(s):  
Polymerase Chain Reaction ◽  
Case Report ◽  
Reverse Transcriptase ◽  
Rt Pcr ◽  
Chain Reaction ◽  
Cutaneous Lesions ◽  
Polymerase Chain ◽  
Systemic Symptoms ◽  
Dermatologic Manifestations

Dermatologic manifestations associated with coronavirus disease 2019 (COVID-19) remain broad and nonspecific. While a surge of “COVID toes” have been reported worldwide, very few cases have been documented in reverse transcriptase-polymerase chain reaction (RT-PCR) confirmed COVID-19 patients. Furthermore, majority of confirmed COVID-19 patients with chilblains-like lesions presented with cutaneous lesions localized to the toes, which was preceded by other systemic symptoms. Our case report describes an occurrence of chilblains-like lesions, limited to the fingers, in an asymptomatic COVID-19 patient confirmed by RT-PCR. 

COVID-19 Reinfection in a Healthcare Worker; Is There a Definitive Immunity Against SARS-CoV-2?

2021 ◽  
Author(s):  
Sayyed Reza Ahmadi ◽  
Saeideh Anvari Ardakani ◽  
Navid Kalani ◽  
Seyed Reza Habibzadeh ◽  
Elnaz Vafadar Moradi ◽  
...  
Keyword(s):  
Polymerase Chain Reaction ◽  
Healthcare Worker ◽  
Nasopharyngeal Swab ◽  
Rt Pcr ◽  
Chain Reaction ◽  
Case Presentation ◽  
Long Period ◽  
Polymerase Chain ◽  
Pcr Test ◽  
First Admission

Introduction: While our knowledge is limited about COVID-19 immunity, recent cases of reinfection have raised concerns. Case presentation: Here, we report a case of COVID-19 reinfection after three months from recovery in a healthcare worker with negative IgM and IgG at the second infection and positive nasopharyngeal swab Reverse transcription polymerase chain reaction (RT-PCR) test despite being discharged with two negative RT-PCR tests at the first admission. Symptoms at first admission were fever, headache, sore throat, diarrhea, and vomiting and got changed to myalgia and anosmia. Conclusion: The strength of this case report is the long period (three months) between the infection and reinfection while other cases reported in literature were reinfected less than one month after their first infection.

scholarly journals A Giant Spontaneous Sub-Capsular Hematoma Of The Liver Revealing A Covid-19 Infection, A Coincidence? A Case Report

2021 ◽  
Author(s):  
Anisse Tidjane ◽  
Amel Laredj ◽  
Nabil Boudjenan-Serradj ◽  
Salim Bensafir ◽  
Benali Tabeti
Keyword(s):  
Polymerase Chain Reaction ◽  
Case Report ◽  
Computerized Tomography ◽  
Reverse Transcription ◽  
Health Condition ◽  
Coagulation Disorder ◽  
Chain Reaction ◽  
First Case ◽  
Traumatic Bleeding ◽  
Polymerase Chain

Hemorrhagic manifestations during COVID-19 infections are increasingly described in the literature. We report the first case of spontaneous subcapsular hematoma of the liver revealing a COVID-19 infection in a 44-year-old woman with no underlying health condition history, a computerized tomography evaluation showed an aspect of lung ground-glass opacities, with moderate impairment estimated about 20%. Reverse transcription-polymerase chain reaction confirmed the diagnosis of COVID-19 infection. During the COVID-19 pandemic, non-traumatic bleeding such as spontaneous hematomas in patients with no coagulation disorder could be a manifestation of COVID-19 infection.

scholarly journals The First Case of COVID-19 Reinfection in Duhok City, Kurdistan Region of Iraq: A Case Report

2020 ◽  
Vol 24 (4) ◽  
Author(s):  
Nawfal Rasheed Hussein ◽  
Dildar H Musa ◽  
Ibrahim Abdulqader Naqid ◽  
Zana Sidiq M.Saleem ◽  
Nashwan Ibrahim
Keyword(s):  
Real Time ◽  
Antiviral Treatment ◽  
Kurdistan Region ◽  
Prevention Strategies ◽  
Rt Pcr ◽  
Chain Reaction ◽  
Community Based ◽  
Case Presentation ◽  
First Case ◽  
Polymerase Chain

Introduction: Coronavirus disease (COVID-19) causes a severe acute respiratory syndrome and is known as coronavirus 2 (SARS-CoV-2), which was first discovered in December, 2019 in Wuhan, China. The question of whether the COVID-19 patients that recover from the disease acquire immunity or are still susceptible to reinfection remains unanswered. Case Presentation: In this study, we presented the case of a 46-year-old male who recovered from the first round of COVID-19 infection. After symptom resolution, two consecutives negative real-time reverse transcription-polymerase chain reaction (RT-PCR) tests confirmed the negativity of the patient. Seven weeks after the first infection, the patient presented with fever and dry cough, and the infection was confirmed using real-time RT-PCR. The reinfection was associated with more severe symptoms, which required antiviral treatment. Conclusions: Our study indicated the possibility of COVID-19 reinfection. If the occurrence of reinfections is confirmed, it may implicate changes in the vaccine and community-based disease prevention strategies. Further studies are required to confirm the possibility of COVID-19 reinfection.

1504: Molecular Diagnosis and Staging of Prostate Cancer Using Clusterin in Real Time Reverse Transcription Polymerase Chain Reaction (RT-PCR)

2006 ◽  
Vol 175 (4S) ◽  
pp. 485-486
Author(s):  
Sabarinath B. Nair ◽  
Christodoulos Pipinikas ◽  
Roger Kirby ◽  
Nick Carter ◽  
Christiane Fenske
Keyword(s):  
Prostate Cancer ◽  
Polymerase Chain Reaction ◽  
Real Time ◽  
Molecular Diagnosis ◽  
Reverse Transcription ◽  
Rt Pcr ◽  
Chain Reaction ◽  
Polymerase Chain
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