scholarly journals Dosimetric proprieties of FBX dosimeter for high energy photon and electron beams

2017 ◽  
Vol 23 (3) ◽  
pp. 55-59
Author(s):  
Ouiza Moussous ◽  
Toufik Medjadj ◽  
Saad Khoudri
Keyword(s):  
Dose Rate ◽  
Dose Response ◽  
Xylenol Orange ◽  
Pure Water ◽  
High Energy ◽  
Good Precision ◽  
Rate Dependency ◽  
Dose Response Relationship ◽  
Γ Rays ◽  
Chemical Dosimeter

Abstract The aim of this work is to characterize the ferrous sulfate-benzoic acid-xylenol orange (FBX) aqueous chemical dosimeter developed at our laboratory, prepared using ultra pure water, by measuring the absorption spectrum, dose response curve, precision and accuracy, energy and dose rate dependency and stability of response. The FBX readings were evaluated by using an accurate spectrophotometer. Experimental data were obtained using various nominal energies 6 MV, 18 MV, 12 MeV, and 15 MeV, including the 60Co γ-rays beam. The calibration of the dosimeters was performed using the ionization chamber as a reference dosimeter. The results show that the FBX dosimeter has a good precision of about 0.2%, no significant energy, dose rate dependence and a linear dose-response relationship in the 1-5 Gy range.

The Effects of Changes in the Rate of Infusion of Vasopressin in Anesthetized Dogs

1971 ◽  
Vol 49 (11) ◽  
pp. 933-940 ◽  
Author(s):  
J. M. Mason ◽  
J. R. Ledsome
Keyword(s):  
Effective Dose ◽  
Dose Rate ◽  
Dose Response ◽  
Response Relationship ◽  
Dose Response Relationship ◽  
Water Diuresis ◽  
Experimental Procedure ◽  
Anesthetic Agents ◽  
Anesthetized Dogs ◽  
Urine Formation

The dose rate of infusion of vasopressin which can be expected to provide maximal effects upon urine formation is difficult to predict in anesthetized dogs. The anesthetic agents, the state of hydration, and the osmolal excretion may all influence the effectiveness of vasopressin. The experiments demonstrate that in moderately hydrated anesthetized dogs when the rate of vasopressin infusion is changed from 0.4 to 0.04 mU/kg min−1 there is a transient dilution of the urine. The lower dose of vasopressin is four times that which completely inhibits water diuresis in conscious dogs and is larger than the dose of 0.025 mU/kg min−1 used in many experiments on anesthetized dogs to eliminate the effects of antidiuretic hormone on the kidney. It appears necessary in experiments in which an attempt is made to eliminate or to assess the effects of vasopressin upon a mechanism producing diuresis either to establish a maximum effective dose for the particular experimental cirmustances, or to examine the dose–response relationship between vasopressin and the diuresis in the particular experimental procedure.

A SUBCUTANEOUS INJECTION ASSAY FOR ANTI-ANDROGENS IN THE CHICK

1962 ◽  
Vol 41 (2) ◽  
pp. 268-273 ◽  
Author(s):  
Ralph I. Dorfman
Keyword(s):  
Dose Response ◽  
Subcutaneous Injection ◽  
Response Relationship ◽  
Dose Response Relationship

ABSTRACT The stimulating action of testosterone on the chick's comb can be inhibited by the subcutaneous injection of 0.1 mg of norethisterone or Ro 2-7239 (2-acetyl-7-oxo-1,2,3,4,4a,4b,5,6,7,9,10,10a-dodecahydrophenanthrene), 0.5 mg of cortisol or progesterone, and by 4.5 mg of Mer-25 (1-(p-2-diethylaminoethoxyphenyl)-1-phenyl-2-p-methoxyphenyl ethanol). No dose response relationship could be established. Norethisterone was the most active anti-androgen by this test.

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