scholarly journals Effect of 1-Octyl-3-Methylimidazolium Salicylate as an Active Pharmaceutical Ingredient (API-IL) on the Thermodynamic Behavior of Aqueous Glycine Solutions at T= 298.15 K

2019 ◽  
Vol 25 (2) ◽  
pp. 154-164
Author(s):  
Hemayat Shekaari ◽  
Mohammed Taghi Zafarani-Moattar ◽  
Seyyedeh Narjes Mirheydari ◽  
Elnaz Mazaher Haji Agha
Keyword(s):  
Ionic Liquid ◽  
Molar Volume ◽  
Partial Molar Volume ◽  
Speed Of Sound ◽  
Active Pharmaceutical Ingredient ◽  
Isentropic Compressibility ◽  
Refractive Indices ◽  
Partial Molar Isentropic Compressibility ◽  
Volume Of Transfer ◽  
B Coefficients

Background: The thermophysical properties of 1-octyl-3-methylimidazolium salicylate as an active pharmaceutical ingredient based on ionic liquid have been investigated in the presence of aqueous solutions of glycine. Therefore, the scope of this article was to determine these properties by measuring the densities, speeds of sound, viscosities, electrical conductances and refractive indices for ternary (glycine + 1-octyl-3-methylimidazolium salicylate + water) soloutions at T = 298.15 K. Methods: A commercial density and speed of sound measurement apparatus was used to measure the density and speed of sound data. Viscosities, electrical conductivities and refractive indices of the studied solutions were measured using digital viscometer, conductivity meter and refractometer, respectively. Results: Variety of properties such as partial molar volume of transfer ∆traV0ϕ, partial molar isentropic compressibility of transfer ∆traK0ϕ, viscosity B-coefficients of transfer ∆traB, ion association constants (KA) and molar refraction RD were determined to investigate the solute-solute and solute-solvent interactions in these systems. Conclusion: The positive values of transfer properties including partial molar volume of transfer (∆traV0ϕ), partial molar isentropic compressibility of transfer (∆traK0ϕ), and viscosity B-coefficients of transfer (∆traB) indicated that in these systems, the ion-polar and polar-polar interactions are dominant. The calculated hydration number showed that dehydration of glycine occurs in presence of this ionic liquid.

scholarly journals Density, speed of sound, refractive index and activity coefficients at infinite dilution for ionic liquids

2018 ◽  
Author(s):  
◽  
Ncomeka Mgxadeni
Keyword(s):  
Refractive Index ◽  
Ionic Liquid ◽  
Molar Volume ◽  
Activity Coefficients ◽  
Speed Of Sound ◽  
Excess Molar Volume ◽  
Infinite Dilution ◽  
Isentropic Compressibility ◽  
Hydrogen Sulfate ◽  
Experimental Density

In this study the experimental density, speed of sound, and refractive index for binary mixtures of an ionic liquid (IL): 1-butyl-3-methylimidazolium nitrate and activity coefficients at infinite dilution of organic solutes in the ionic liquid: 1-butyl-3-methylimidazolium hydrogen sulfate were determined. The density, speed of sound, and refractive index of 1-butyl-3-methylimidazolium nitrate in pyridine or acetonitrile or thiophene have been reported at T = 298.15 K, 303.15 K, 308.15 K, 313.15 K and 318.15 K using an Anton Paar DSA 5000M vibrating U-tube densimeter and a RXA 156 refractometer. The derived properties namely: excess molar volume, isentropic compressibility and change in refractive index were calculated from density, speed of sound and refractive index, respectively. The results are discussed in terms of molecular interactions (hydrogen bond, dipole-dipole, or ion-solvent or interactions). The negative deviation of excess molar volume and the positive deviation in change in refractive index clearly indicates the strong interaction of 1-butyl-3-methylimidazolium nitrate with pyridine or acetonitrile or thiophene in solution. The positive values of isentropic compressibility for the system indicates that the mixtures were more compressible than the ideal mixture. The Redlich Kister smoothing polynomial was used to fit the excess molar volume and deviation in isentropic compressibility data. The Lorentz-Lorenz equation was used to predict the experimental density, or refractive index data and to correlate the excess molar volume. Gas liquid chromatography was used to determine activity coefficients at infinite dilution for 28 polar and non-polar organic solute: alkanes, cycloalkanes, alkenes, alkynes, aromatic hydrocarbons, alcohols, aldehydes, thiophene, pyridine and acetonitrile in an IL: 1-butyl-3- methylimidazolium hydrogen sulfate ([BMIM][HSO4]). The measured values of activity coefficients at infinite dilution for the solutes in [BMIM][HSO4] were carried out at T = (313.15, 323.15, 333.15) K. Partial molar excess enthalpies at infinite dilution of the organic solutes in the ionic liquid have been calculated from the temperature dependence of activity coefficients at infinite dilution. The selectivity and capacity values for separation problems namely: hexane/benzene, heptane/benzene, cyclohexane/benzene, ethanol/benzene, heptane/pyridine, heptane/thiophene and methanol/acetone at T = 323.15 K were calculated and compared to literature values for similar ionic liquids, sulfolane and N-methyl-2- pyrolidinone (NMP). The IL [BMIM][HSO4] gave both the highest selectivity and limiting capacity for the heptane/thiophene separation and would therefore be a suitable entrainer for this separation. New data from this study reveals that [BMIM][HSO4] may be proposed as a replacement solvent for the separation of sulphur or nitrogen compounds from alkanes.

Thermodynamic behaviour of adenosine in water–DMSO mixtures in the presence of K+ and Ca2+ ions at 25, 30, 35, and 40 °C

1985 ◽  
Vol 63 (6) ◽  
pp. 1180-1184 ◽  
Author(s):  
Anil K. Puri
Keyword(s):  
Transition State ◽  
Viscous Flow ◽  
Molar Volume ◽  
Partial Molar Volume ◽  
Activation Parameters ◽  
Volume Formula ◽  
Thermodynamic Behaviour ◽  
Partial Molar Compressibility ◽  
Viscosity B Coefficient ◽  
B Coefficients

Partial molar volume [Formula: see text] partial molar compressibility [Formula: see text] Jones–Dole viscosity B coefficient, and solute activation parameters of adenosine in water–DMSO mixtures in the presence of Ca2+ and K+ ions have been calculated from ultrasonic, volumetric, and viscometric studies at 25, 30, 35, and 40 °C(± 0.01° C). The results are discussed in terms of the Jones–Dole viscosity B coefficients and the transition state parameters for viscous flow.

scholarly journals Thermoacoustic, Volumetric, and Viscometric Investigations in Binary Liquid System of Cyclohexanone with Benzyl Benzoate at T = 308.15, 313.15, and 318.15 K

2014 ◽  
Vol 2014 ◽  
pp. 1-13 ◽  
Author(s):  
Sk. Md Nayeem ◽  
M. Kondaiah ◽  
K. Sreekanth ◽  
D. Krishna Rao
Keyword(s):  
Molar Volume ◽  
Partial Molar Volume ◽  
Infinite Dilution ◽  
Partial Molar Volumes ◽  
Isentropic Compressibility ◽  
Liquid Mixtures ◽  
Liquid System ◽  
Benzyl Benzoate ◽  
Molar Volumes ◽  
Binary Liquid

Ultrasonic velocities (u), densities (ρ), and viscosities (η) of binary liquid mixtures of cyclohexanone with benzyl benzoate, including pure liquids, over the entire composition range have been measured at 308.15 K, 313.15 K, and 318.15 K. Using the experimental results, parameters such as molar volume (Vm), isentropic compressibility (ks), intermolecular free length (Lf), acoustic impedance (Z), internal pressure (πi), enthalpy (H), Gibbs free energy of activation of viscous flow (G*E), and excess/deviation properties of these including partial molar volumes (V-m,1 and V-m,2), excess partial molar volumes (V-m,1E and V-m,2E), partial molar volume of the components at infinite dilution (V-m,1∞, V-m,2∞), and excess partial molar volume at infinite dilution (V-m,1E,∞and V-m,2E,∞) have been computed. The observed negative values of VmE, Δks, LfE, and πiE and positive values of zE, HE, ΔG*E, Δη, and Δu for all the liquid mixtures studied clearly indicate the presence of strong dipole-dipole-type interactions, fitting of smaller molecules into bigger molecules. Further theoretical values of sound velocity and viscosity in the mixtures have been evaluated using various theories and have been compared with experimental values to verify the applicability of such theories to the systems studied.

Interactions of Drug Doxycycline Hyclate with Galactitol in Aqueous Solutions at Different Temperatures by Volumetric and Acoustic Methods

2020 ◽  
Vol 234 (11-12) ◽  
pp. 1853-1874
Author(s):  
Shashi Kant Lomesh ◽  
Vikas Nathan ◽  
Madhu Bala ◽  
Inesh Kumar
Keyword(s):  
Molar Volume ◽  
Apparent Molar Volume ◽  
Isentropic Compressibility ◽  
Doxycycline Hyclate ◽  
Isentropic Compression ◽  
Acoustic Methods ◽  
Different Temperatures ◽  
Volume Of Transfer ◽  
Experimental Values ◽  
Molar Expansibility

AbstractThe experimental values of density, ρ and speed of sound, u of doxycycline hyclate drug (0.002–0.014) mol kg−1 in water and (0.1, 0.2 and 0.4) mol kg−1 of aqueous galactitol solutions at temperatures T = (303.15, 308.15 and 313.15) K and at atmospheric pressure have been reported in the present communication. From the experimental values, various derived parameters such as apparent molar volume (ΦV), apparent molar isentropic compression (ΦK), limiting apparent molar volume ($\phi_{\text{v}}^{\text{o}}$), limiting apparent molar isentropic compression ($\phi_{\text{K}}^{\text{o}}$), limiting apparent molar volume of transfer (Δ$\phi_{\text{V}}^{\text{O}}$), limiting apparent molar isentropic compression of transfer (Δ$\phi_{\text{K}}^{\text{O}}$), limiting apparent molar expansibility ($\phi_{\text{E}}^{\text{o}}$), thermal expansion coefficient (α) and acoustic parameters like isentropic compressibility $({{\kappa}_{\text{S}}})$, intermolecular free length (Lf), and specific acoustic impedance (Z) were calculated. The structure-making behaviour of DH in aqueous galactitol solution was determined on the basis of Hepler’s Equation i.e. on the basis of sign of ${\left({\frac{{{{\text{d}}^{2}}\phi_{\text{V}}^{\text{O}}}}{{{\text{d}}{{\text{T}}^{2}}}}}\right)_{\text{P}}}$. The various derived parameters were utilised to interpret the molecular interactions i.e. solute–solute and solute–solvent existing in the studied system.

Solvent Effect on the Enthalpy of Solution and Partial Molar Volume of the Ionic Liquid 1-Butyl-3-methylimidazolium Tetrafluoroborate

2012 ◽  
Vol 41 (8) ◽  
pp. 1375-1387 ◽  
Author(s):  
Vladimir D. Kiselev ◽  
Helena A. Kashaeva ◽  
Ilzida I. Shakirova ◽  
Lubov’ N. Potapova ◽  
Alexander I. Konovalov
Keyword(s):  
Ionic Liquid ◽  
Solvent Effect ◽  
Molar Volume ◽  
Partial Molar Volume ◽  
Enthalpy Of Solution
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