The impact of body mass index on serum androgen and leptin association in reproductive age women

Iron deficiency anemia (IDA) is one of the causes of chronic fatigue with a decrease in the quality of life, impaired cognitive function and poor labor productivity. Obesity as a condition of chronic low-intensity inflammation is one of the factors that increases the risk of anemia and impairs the quality of life in the general population. We drew attention to the high global prevalence of anemia among pregnant women of reproductive age in the world and the prevalence of high body mass index among women compared to men in most countries. The objective of the work was to determine the impact of obesity on clinical features and quality of life of women with ІDA. We analyzed the main markers of ІDA and hematologic indices in women with obesity (n = 30) compared with the control group (n = 10), where there were women with ІDA but without obesity. It was found that there was no statistical difference between these parameters, but nevertheless, the serum ferritin level in obese women was (4.70 ± 2.68) ng/ml compared to (3.50 ± 2.93) ng/ml and had a significant positive correlation with body mass index. The analysis of the questionnaires revealed that obesity is still a significant factor in women with ІDA and obesity, which determines the decrease in quality of life mainly in the physical aspect in the absence of significant influence on the psychosocial components of health.

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Assessment of Psycho-emotional Distress Due to Age, Body Mass Index, and Marital Status in Polycystic Ovary Syndrome in North Indian Population

International Journal of Women s Health and Reproduction Sciences ◽

10.15296/ijwhr.2020.59 ◽

2020 ◽

Vol 8 (4) ◽

pp. 368-375

Author(s):

Fauzia Tabassum ◽

Hemali Heidi Sinha ◽

Kavita Dhar ◽

Chandra Jyoti ◽

Md Sayeed Akhtar ◽

...

Keyword(s):

Body Mass Index ◽

Body Weight ◽

Polycystic Ovary Syndrome ◽

Marital Status ◽

Body Mass ◽

Polycystic Ovary ◽

Reproductive Age ◽

Ovary Syndrome ◽

Significant Difference ◽

The Impact

Objectives: Polycystic ovary syndrome (PCOS) is a multifaceted endocrine disorder in reproductive age having a greater impact on health-related quality of life (HRQOL). The aim of this study was to find out PCOS demographics and its related HRQOL effects for improving psychological understanding in disease management. Materials and Methods: A prospective questionnaire-based study was conducted for a period of twelve months at All India Institute of Medical Sciences, Patna, India. The data of 100 PCOS cases were collected about socio-demographic status, clinical history, and dietary intake. Then, a validated PCOS questionnaire (PCOSQ) was used to observe the impact of PCOS symptoms on patients’ HRQOL. Results: The overall 57% and 48% of PCOS cases belonged to the age range of 20-30 years and had a body mass index (BMI) of >25-30, respectively. Based on the results, a significant difference was observed in the mean score of PCOSQ vs. marital status in PCOS cases with respect to emotion (P=0.039), body weight (P=0.002), and infertility (P=0.001). Furthermore, the result showed a significant difference in the domain of emotion (P=0.008), body hair (P=0.035), body weight (P<0.001), and infertility (P=0.018) among BMI group, and a high score was observed in the BMI group <18 in comparison to the other groups of BMI. Conclusions: In general, our findings indicated that infertility, emotions, and BMI had extremely higher impacts on the HRQOL of women suffering from PCOS although their educational status failed to affect HRQOL.

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Associations of Asthma with Body Mass Index and Adult Weight Change among Reproductive Age Women

Journal of Asthma ◽

10.3109/02770903.2011.604885 ◽

2011 ◽

Vol 48 (7) ◽

pp. 701-706 ◽

Cited By ~ 3

Author(s):

Neway Gessesse Fida ◽

Daniel A. Enquobahrie ◽

Bizu Gelaye ◽

Chunfang Qiu ◽

Michelle A. Williams

Keyword(s):

Body Mass Index ◽

Body Mass ◽

Weight Change ◽

Reproductive Age ◽

Adult Weight ◽

Reproductive Age Women

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Serum anti-müllerian hormone concentrations in reproductive age women with and without polycystic ovary syndrome: the influence of body mass index

Reproductive Medicine and Biology ◽

10.1007/s12522-011-0078-5 ◽

2011 ◽

Vol 10 (2) ◽

pp. 113-120 ◽

Cited By ~ 11

Author(s):

Sezai Sahmay ◽

Onur Guralp ◽

Levent M. Senturk ◽

Metehan Imamoglu ◽

Mustafa Kucuk ◽

...

Keyword(s):

Body Mass Index ◽

Polycystic Ovary Syndrome ◽

Body Mass ◽

Polycystic Ovary ◽

Reproductive Age ◽

Ovary Syndrome ◽

Reproductive Age Women

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Features of the hormonal profile in obese reproductive-age women

Fundamental and Clinical Medicine ◽

10.23946/2500-0764-2020-5-3-77-84 ◽

2020 ◽

Vol 5 (3) ◽

pp. 77-84

Author(s):

N. V. Artymuk ◽

O. A. Tachkova ◽

N. A. Sukhova

Keyword(s):

Insulin Resistance ◽

Body Mass Index ◽

Body Mass ◽

Density Lipoprotein ◽

Dehydroepiandrosterone Sulfate ◽

Reproductive Age ◽

Obese Women ◽

Women Of Reproductive Age ◽

Hormonal Profile ◽

Reproductive Age Women

Aim. To assess the hormonal profile features in obese reproductive-age women. Materials and Methods. We consecutively enrolled 163 women of reproductive age (140 women with body mass index ≥ 30 kg/m2 and 23 women with normal body mass index) who have been admitted to Podgorbunskiy Regional Emergency Medicine Hospital. All patients of both groups underwent general and gynecological examination. Serum levels of follicle-stimulating hormone (FSH), luteinizing hormone (LH), prolactin, estradiol, estrone, testosterone, dehydroepiandrosterone sulfate, thyroid-stimulating hormone, free triiodothyronine, total and free thyroxine, cortisol, leptin, immunoreactive insulin, and progesterone were assessed on days 5-6 and 21-22 of the menstrual cycle. Results. Obese women of reproductive age were characterised by higher values of LH, LH/ FSH ratio, testosterone, estradiol, estrone, leptin, IRI and by lower levels of FSH and progesterone compared with normal weight women. A direct correlation was found between the level of leptin and estrone (r = 0.21, p = 0.014), insulin resistance (r = 0.18, p = 0.039), triglycerides (r = 0.20, p = 0.030), and low-density lipoprotein cholesterol (r = 0.22, p = 0.016). There was a statistically significant inverse correlation between the level of leptin and high-density lipoprotein cholesterol (r = -0.18, p = 0.043). A direct correlation was established between insulin and LH (r = 0.24, p = 0.030), testosterone (r = 0.32, p = 0.037), dehydroepiandrosterone sulfate (r = 0.56, p = 0.003), insulin resistance (r = 0.95, p < 0.001), cholesterol (r = 0.20, p = 0.024), triglycerides (r = 0.29, p < 0.001). Conclusion. Obese women of reproductive age have certain hormonal features that underlie menstrual and reproductive disorders in these patients.

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