scholarly journals Effects of Lorazepam and Citalopram on Human Defensive Reactions: Ethopharmacological Differentiation of Fear and Anxiety

2009 ◽  
Vol 29 (40) ◽  
pp. 12617-12624 ◽  
Author(s):  
A. M. Perkins ◽  
U. Ettinger ◽  
R. Davis ◽  
R. Foster ◽  
S. C. R. Williams ◽  
...  
Keyword(s):  
Defensive Reactions ◽  
Fear And Anxiety

Intercollicular nucleus electric stimulation encoded “walk forward” commands in pigeons

2018 ◽  
Vol 68 (2) ◽  
pp. 213-225 ◽  
Author(s):  
Hui Wang ◽  
Junqing Yang ◽  
Changzhi Lv ◽  
Ruituo Huai ◽  
Yuxia Li
Keyword(s):  
Response Time ◽  
Electric Stimulation ◽  
Periaqueductal Gray ◽  
Research Field ◽  
Defensive Reactions ◽  
Straight Line ◽  
Satisfactory Method ◽  
Fear And Anxiety ◽  
Stimulation Of

AbstractThe bio-robot research field is growing. Robo-pigeons have been successfully programmed to turn left or right; however, a satisfactory method of commanding a robo-pigeon to walk forward is still lacking. This problem has become a roadblock to progress in bio-robot research and applications. In mammals, the midbrain periaqueductal gray region (PAG) plays a key role in mediating defensive reactions in response to fear and anxiety. The avian intercollicular nucleus (ICo) is thought to correspond to the PAG. In this study, we found that microstimulating the ICo could successfully induce a robo-pigeon to walk forward. Compared with stimulation of the previously used archistriatum, the response time was considerably shorter and the behavior accuracy significantly higher. This paper describes in detail the process of controlling a robo-pigeon such that it walks forward and backward along a prescribed straight line. From the results, we draw the conclusion that the ICo is suitable for prompting the “walk forward” order in robo-pigeons.

A Confirmatory Factor Analytic Study of Anxiety, Fear, and Behavioral Inhibition System Measures

2007 ◽  
Vol 28 (4) ◽  
pp. 179-187 ◽  
Author(s):  
Andrew J. Cooper ◽  
Adam M. Perkins ◽  
Philip J. Corr
Keyword(s):  
Trait Anxiety ◽  
Behavioral Inhibition ◽  
Discriminant Validity ◽  
Self Report ◽  
Behavioral Inhibition System ◽  
Reinforcement Sensitivity Theory ◽  
Factor Analytic ◽  
Confirmatory Factor ◽  
Structural Invariance ◽  
Fear And Anxiety

Abstract. Recent revisions to the reinforcement sensitivity theory (RST) of personality have highlighted the distinction between the emotions of fear and anxiety. These revisions have substantial implications for self-report measurement; in particular, they raise the question of whether separate traits of fear and anxiety exist and, if so, their interrelationship. To address this question, the current study used confirmatory factor analytic procedures to examine the convergent and discriminant validity of measures of trait anxiety, fear, and the behavioral inhibition system (BIS). We also examined measurement and structural invariance across gender in 167 males and 173 females who completed the Spielberger State-Trait Anxiety Inventory (STAI), the Carver and White BIS Scale, and the Fear Survey Schedule (FSS). The findings suggested that trait anxiety and the BIS scale are relatively distinct from Tissue Damage Fear (FSS). Further, the final model showed measurement and structural invariance across gender. The implications of the results for future self-report assessment in RST research are discussed.

Fear and anxiety: Theoretical distinction and clinical test

1996 ◽  
Author(s):  
Bruce N. Cuthbert ◽  
Margaret M. Bradley ◽  
Peter J. Lang
Keyword(s):  
Clinical Test ◽  
Fear And Anxiety

Psychological influences on wound healing

2019 ◽  
Vol 98 (8) ◽  
pp. 312-314
Keyword(s):  
Wound Healing ◽  
Enhanced Recovery ◽  
Enhanced Recovery After Surgery ◽  
Wound Complications ◽  
State Of Mind ◽  
Life Threatening ◽  
Psychological Influences ◽  
Fear And Anxiety ◽  
Care Costs

Surgical wound complications remain a major cause of morbidity; although usually not life threatening, they reduce the quality of life. They are also associated with excessive health care costs. Wound healing is affected by many factors – wound characteristics, infection, comorbidities and nutritional status of the patient. In addition, though, psychological stress and depression may decrease the inflammatory response required for bacterial clearance and so delay wound healing, as well. Although the patient´s state of mind can be influenced only to a certain extent, we should nevertheless stick to ERAS (Enhanced Recovery After Surgery) guidelines and try to diminish fear and anxiety by providing enough information preoperatively, pay due attention to postoperative analgesia and seek to provide an agreeable environment.

A review on aversive Pavlovian-to-Instrumental transfer in humans

2020 ◽  
Author(s):  
Anna Gerlicher ◽  
Merel Kindt
Keyword(s):  
Avoidance Behavior ◽  
Neural Circuits ◽  
Transfer Effects ◽  
Future Directions ◽  
Transfer Paradigm ◽  
Wide Range ◽  
Threat Cues ◽  
Imminent Threat ◽  
Fear And Anxiety ◽  
Pathological Anxiety

A cue that indicates imminent threat elicits a wide range of physiological, hormonal, autonomic, cognitive, and emotional fear responses in humans and facilitates threat-specific avoidance behavior. The occurrence of a threat cue can, however, also have general motivational effects and affect behavior. That is, the encounter with a threat cue can increase our tendency to engage in general avoidance behavior that does neither terminate nor prevent the threat-cue or the threat itself. Furthermore, the encounter with a threat-cue can substantially reduce our likelihood to engage in behavior that leads to rewarding outcomes. Such general motivational effects of threat-cues on behavior can be informative about the transition from normal to pathological anxiety and could also explain the development of comorbid disorders, such as depression and substance abuse. Despite the unmistakable relevance of the motivational effects of threat for our understanding of anxiety disorders, their investigation is still in its infancy. Pavlovian-to-Instrumental transfer is one paradigm that allows us to investigate such motivational effects of threat cues. Here, we review studies investigating aversive transfer in humans and discuss recent results on the neural circuits mediating Pavlovian-to-Instrumental transfer effects. Finally, we discuss potential limitations of the transfer paradigm and future directions for employing Pavlovian-to-Instrumental transfer for the investigation of motivational effects of fear and anxiety.

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