scholarly journals Relationship Between Alcohol Drinking and Aspartate Aminotransferase:Alanine Aminotransferase (AST:ALT) Ratio, Mean Corpuscular Volume (MCV), Gamma-Glutamyl Transpeptidase (GGT), and Apolipoprotein A1 and B in the U.S. Population*

2010 ◽  
Vol 71 (2) ◽  
pp. 249-252 ◽  
Author(s):  
Suthat Liangpunsakul ◽  
Rong Qi ◽  
David W. Crabb ◽  
Frank Witzmann
Keyword(s):  
Alcohol Drinking ◽  
Mean Corpuscular Volume ◽  
Apolipoprotein A1 ◽  
Corpuscular Volume ◽  
Gamma Glutamyl Transpeptidase ◽  
Gamma Glutamyl ◽  
Glutamyl Transpeptidase ◽  
The U.S

Gamma Glutamyl Transpeptidase and Mean Corpuscular Volume: Their Usefulness in the Assessment of In-Patient Alcoholics

1986 ◽  
Vol 149 (3) ◽  
pp. 353-356 ◽  
Author(s):  
Richard W. Latcham
Keyword(s):  
Mean Corpuscular Volume ◽  
Problem Drinking ◽  
Corpuscular Volume ◽  
Gamma Glutamyl Transpeptidase ◽  
Gamma Glutamyl ◽  
Psychiatric Beds ◽  
Glutamyl Transpeptidase

Gamma glutamyl transpeptidase and mean corpuscular volume are shown to be of little value in the assessment of patients admitted to psychiatric beds for problem drinking.

Effect of Drinking on Correlations between Biochemical Variables

1981 ◽  
Vol 18 (3) ◽  
pp. 143-145 ◽  
Author(s):  
J B Whitfield ◽  
J K Allen ◽  
M A Adena ◽  
W J Hensley
Keyword(s):  
Uric Acid ◽  
Alcohol Consumption ◽  
Mean Corpuscular Volume ◽  
Laboratory Tests ◽  
Clinical Laboratory ◽  
Corpuscular Volume ◽  
Test Results ◽  
Gamma Glutamyl Transpeptidase ◽  
Highly Correlated ◽  
Glutamyl Transpeptidase

Several clinical laboratory tests correlate with alcohol consumption, for example, the plasma activities of gamma-glutamyl transpeptidase (GGT) and aspartate aminotransferase (AST), the concentrations of triglycerides (TG) and uric acid (UA) and the erythrocyte mean corpuscular volume (MCV). The correlations of these test results with each other have been studied in a population of men attending a multiphasic health-screening centre. The patterns of correlation were of two types: those between the pairs of variables GGT/TG, GGT/UA, TG/AST, and TG/UA were all unchanged as the level of alcohol consumption increased; the pairs of variables GGT/MCV, UA/AST, AST/MCV, UA/MCV, and GGT/AST all became more highly correlated as the level of alcohol consumption increased.

Some Laboratory Correlates of Drinking Habits

1978 ◽  
Vol 15 (1-6) ◽  
pp. 297-303 ◽  
Author(s):  
J. B. Whitfield ◽  
W. J. Hensley ◽  
D. Bryden ◽  
H. Gallagher
Keyword(s):  
Aspartate Aminotransferase ◽  
Mean Corpuscular Volume ◽  
Alcohol Intake ◽  
Liver Function Tests ◽  
Corpuscular Volume ◽  
Test Results ◽  
Gamma Glutamyl Transpeptidase ◽  
Frequency Distributions ◽  
Drinking Habits ◽  
Glutamyl Transpeptidase

The effect of drinking habits on the frequency distributions of eight biochemical or haematological test results was studied in 7915 patients attending a multiphasic health testing centre. Increasing incidences of abnormal results with increasing alcohol intake, at levels of alcohol intake habitual for a large proportion of the population, were found for plasma gamma-glutamyl transpeptidase, triglycerides and uric acid, and for erythrocyte mean corpuscular volume. Of four frequently used liver function tests, aspartate aminotransferase, alkaline phosphatase, bilirubin, and albumin, only aspartate aminotransferase was strongly affected by drinking habits. These findings have relevance for the detection of individuals whose drinking habits are harmful to them, and for the interpretation of ‘profile’ results.

scholarly journals A Case Report of Alcoholic Liver Disease with Jaundice Treated with Korean Medicine

2021 ◽  
Vol 42 (5) ◽  
pp. 949-957
Author(s):  
Jae-yoon Ahn ◽  
Sang-song Sim ◽  
Sol Jeong ◽  
Yong-jeen Shin ◽  
Kang-san Kim ◽  
...  
Keyword(s):  
Alkaline Phosphatase ◽  
Liver Disease ◽  
Alcoholic Liver Disease ◽  
Mean Corpuscular Volume ◽  
Total Bilirubin ◽  
Corpuscular Volume ◽  
Gamma Glutamyl Transpeptidase ◽  
Korean Medicine ◽  
Blood Tests ◽  
Glutamyl Transpeptidase

Objective: This study aimed to report a case of alcoholic liver disease with jaundice that was improved with Korean medicine treatment.Methods: A patient who developed jaundice due to continuous drinking was treated with herbal medicine, acupuncture, moxibustion, and cupping. Blood tests were performed to measure the levels of aspartate aminotransferase (AST), alanine aminotransferase (ALT), alkaline phosphatase (ALP), gamma glutamyl transpeptidase (γ-GTP), total bilirubin, albumin, and total protein; AST/ALT ratio; and mean corpuscular volume (MCV). Jaundice parameters were subjectively recorded at 3-day intervals.Results: After treatment, the AST, ALT, ALP, γ-GTP, and total bilirubin levels; MCV; and jaundice were decreased.Conclusion: Korean medicine treatment appeared to be an effective method for alcoholic liver disease with jaundice.

Relationship Between Gamma-glutamyl Transpeptidase Activity and Inflammatory Response in Lichen Planus

2018 ◽  
Vol 69 (3) ◽  
pp. 739-743 ◽  
Author(s):  
Madalina Irina Mitran ◽  
Ilinca Nicolae ◽  
Corina Daniela Ene ◽  
Cristina Iulia Mitran ◽  
Clara Matei ◽  
...  
Keyword(s):  
Inflammatory Response ◽  
Lichen Planus ◽  
Inflammatory Process ◽  
Molecular Mechanisms ◽  
Functional Adaptation ◽  
Physical Factors ◽  
Inflammatory Disorder ◽  
Gamma Glutamyl Transpeptidase ◽  
Gamma Glutamyl ◽  
Glutamyl Transpeptidase

Chemicals used in the manufacture of synthetic fibers have been associated with undesirable side effects such as itching or skin lesions and it seems that they are involved in the induction of pathological processes such as oxidative stress and inflammation. Lichen planus (LP) can be regarded as an inflammatory disorder, chemical and physical factors playing an important role in the perpetuation of the inflammatory process. Gamma-glutamyl transpeptidase (GGT) plays an important role in the preservation of skin architecture and modulation of skin inflammation. In this study, we found that GGT activity is increased in LP patients with mild inflammation, whilst GGT is inactivated under conditions of severe inflammation. Therefore, GGT is involved in the inflammatory process, but there is no a positive correlation between its activity and the intensity of the inflammatory response. This functional adaptation of the enzyme may be due to down-regulation of its synthesis under free radical overload conditions. Understanding the molecular mechanisms involved in the modulation of intracellular redox homeostasis is an important step in the pharmacological management of patients with LP.

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