scholarly journals Advances in diagnostic practices affect thyroid cancer incidence in France

2004 ◽  
pp. 133-139 ◽  
Author(s):  
L Leenhardt ◽  
MO Bernier ◽  
MH Boin-Pineau ◽  
B Conte Devolx ◽  
R Marechaud ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Cancer Incidence ◽  
Thyroid Diseases ◽  
Proportional Hazard ◽  
Clinical Practices ◽  
Cancer Prevalence ◽  
Diagnostic Practices ◽  
The Impact ◽  
Thyroid Cancer Incidence ◽  
Over Time

OBJECTIVE: To analyse trends in diagnostic practices of thyroid diseases and to relate them to the increase in thyroid cancer incidence in France over time. DESIGN: From 1980 to 2000, a French retrospective multicentric (three endocrinology and three nuclear medicine centres) study of thyroid diseases was conducted on 20 consecutive unselected patients' records, sampled every 5 years in each centre. METHODS: Characteristics of the population and diagnosis procedures (thyroid ultrasonography (US), radionuclide scan, cytology and hormonal measurements) were described over time. Changing trends in operated patients and in cancer prevalence were analysed as well as the impact of practices on cancer incidence. RESULTS: The study included 471 patients (82% female, mean age 46.7, range 9-84 years), referred for nodular thyroid diseases (66.7%) or thyroid dysfunctions (33.3%). A significant increase in US (3 to 84.8%) and cytological practices (4.5 to 23%), and a decrease (89.4 to 49.6%) in radionuclide scan procedures were observed over time. Although the proportion of patients undergoing surgery remained constant (24.8%), the prevalence of cancer increased among operated patients from 12.5 to 37% (P=0.006). In a Cox's proportional hazard model stratified on the clinical characteristics of patients, only the cytological practice, regardless of its results, was significantly associated with the occurrence of cancer: relative risk (RR)=4.4 (95% confidence interval (CI): 1.1-16; P=0.04). CONCLUSIONS: From 1980 to 2000, a major evolution in clinical practices has led to the increase in thyroid cancer reported in France. Such changes in medical, as well as in surgical and pathological, practices must be taken into account in incidence measurement.

Assessment of the Risk of Thyroid Cancer in Rural Settlements in the Areas of the Bryansk Region (Russia) Affected by the Chernobyl NPP Accident

2021 ◽  
Author(s):  
Vladimir Baranchukov ◽  
Elena Korobova ◽  
Alexander Silenok ◽  
Irina Kurnosova
Keyword(s):  
Thyroid Cancer ◽  
Thyroid Gland ◽  
Cancer Incidence ◽  
Rural Areas ◽  
Urban Areas ◽  
The United States ◽  
Food Sources ◽  
Rural Settlements ◽  
The Impact ◽  
Thyroid Cancer Incidence

<p>Thyroid cancer is one of the most important medical problems. The disease often occurs in regions that have been exposed to radiation and where there is insufficient iodine in nature. Adequate intake of iodine is necessary for the functioning of the thyroid gland and the development of the mammalian fetus. Thus, in 1990, a special International Council for Combating Iodine Deficiency Disorders was established at WHO. Since 1990, the incidence of thyroid cancer in the world has increased by 169% (Dang et al., 2020). It can be assumed that such an increase is associated with early detection of the disease. However, in countries with high human development index (HDI), where the detection rate of the disease is 4-5 times higher than in low HDI countries, this indicator does not correlate with mortality from thyroid cancer. In our opinion, this is because the food sources must be considered. As local foods to the diet varies significantly between urban and rural areas, it is important to compare cases of thyroid cancer in them. For example, in rural areas of the United States, the overall incidence of thyroid cancer is 14% lower than in cities (McDow et al., 2020).</p><p>For the Bryansk region (the most affected by the Chernobyl accident in Russia) data on thyroid cancer also show a difference: in 27 regional centers (67% of the population), an estimate of the thyroid cancer incidence is 20.9 per 100 000 people per year (period from 1990 to 2019), while for other localities the rate is much lower (16.3). However, mortality from thyroid cancer in rural areas is 46% higher than in urban areas (0.89 and 0.60, respectively). Using a specialized GIS developed to study natural and man-made geochemical factors responsible for the spread of endemic diseases, we zoned the territory according to evaluated risk (Baranchukov et al., 2019).</p><p>Assessment of the risk of thyroid cancer turned out to be more effective for rural settlements (excluding the most contaminated area, where special measures were taken): the correlation between the calculated total natural and man-made risk and the incidence of thyroid cancer was significant and higher in rural areas (r=0.54, p=0.05, n=25) than in the main urban areas (r=0.27; p=0.17). The result of the study shows that the prevalence of thyroid cancer is associated, first of all, not with the level of diagnosis, but with the structure of nutrition, which ensures the entry of elements into the human body.</p><p>This study was funded by RFBR and BRFBR, project #20-55-00012.</p><p>References</p><p>Deng Y et al. Global Burden of Thyroid Cancer From 1990 to 2017. JAMA Netw Open. 2020;3(6):e208759. Published 2020 Jun 1. doi:10.1001/jamanetworkopen.2020.8759</p><p>McDow AD, et al. Impact of Rurality on National Trends in Thyroid Cancer Incidence and Long-Term Survival. J Rural Health. 2020 Jun;36(3):326-333. doi: 10.1111/jrh.12374. Epub 2019 May 17. PMID: 31099945</p><p>Baranchukov V et al. Application of Geoinformation Technologies for minimization of thyroid gland diseases in the impact areas of the radioiodine fallout, EGU General Assembly 2020, Online, 4–8 May 2020, EGU2020-9000, https://doi.org/10.5194/egusphere-egu2020-9000, 2020</p>

scholarly journals Global trends in thyroid cancer incidence and the impact of overdiagnosis

2020 ◽  
Vol 8 (6) ◽  
pp. 468-470 ◽  
Author(s):  
Mengmeng Li ◽  
Luigino Dal Maso ◽  
Salvatore Vaccarella
Keyword(s):  
Thyroid Cancer ◽  
Cancer Incidence ◽  
Global Trends ◽  
The Impact ◽  
Thyroid Cancer Incidence

Temporal and geographical variations of thyroid cancer incidence and mortality in France during 1986–2015: The impact of overdiagnosis

2021 ◽  
Vol 75 ◽  
pp. 102051
Author(s):  
Mengmeng Li ◽  
Patricia Delafosse ◽  
Filip Meheus ◽  
Françoise Borson-Chazot ◽  
Jean-Christophe Lifante ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Cancer Incidence ◽  
Geographical Variations ◽  
Incidence And Mortality ◽  
The Impact ◽  
Thyroid Cancer Incidence

scholarly journals Thyroid Ultrasound and the Increase in Diagnosis of Low-Risk Thyroid Cancer

2018 ◽  
Vol 104 (3) ◽  
pp. 785-792 ◽  
Author(s):  
Megan R Haymart ◽  
Mousumi Banerjee ◽  
David Reyes-Gastelum ◽  
Elaine Caoili ◽  
Edward C Norton
Keyword(s):  
Thyroid Cancer ◽  
Papillary Thyroid Cancer ◽  
Cancer Incidence ◽  
The United States ◽  
Low Risk ◽  
Thyroid Ultrasound ◽  
Papillary Thyroid ◽  
Initial Imaging ◽  
Thyroid Cancer Incidence ◽  
Over Time

Abstract Context Thyroid cancer incidence increased with the greatest change in adults aged ≥65 years. Objective To determine the relationship between area-level use of imaging and thyroid cancer incidence over time. Design, Setting and Participants Longitudinal imaging patterns in Medicare patients aged ≥65 years residing in Surveillance, Epidemiology, and End Results (SEER) regions were assessed in relationship to differentiated thyroid cancer diagnosis in patients aged ≥65 years included in SEER-Medicare. Linear mixed-effects modeling was used to determine factors associated with thyroid cancer incidence over time. Multivariable logistic regression was used to determine patient characteristics associated with receipt of thyroid ultrasound as initial imaging. Main Outcome Measure Thyroid cancer incidence. Results Between 2002 and 2013, thyroid ultrasound use as initial imaging increased (P < 0.001). Controlling for time and demographics, use of thyroid ultrasound was associated with thyroid cancer incidence (P < 0.001). Findings persisted when cohort was restricted to papillary thyroid cancer (P < 0.001), localized papillary thyroid cancer (P = 0.004), and localized papillary thyroid cancer with tumor size ≤1 cm (P = 0.01). Based on our model, from 2003 to 2013, at least 6594 patients aged ≥65 years were diagnosed with thyroid cancer in the United States due to increased use of thyroid ultrasound. Thyroid ultrasound as initial imaging was associated with female sex and comorbidities. Conclusion Greater thyroid ultrasound use led to increased diagnosis of low-risk thyroid cancer, emphasizing the need to reduce harms through reduction in inappropriate ultrasound use and adoption of nodule risk stratification tools.

The Impact of Diagnostic Changes on the Rise in Thyroid Cancer Incidence: A Population-Based Study in Selected High-Resource Countries

Thyroid ◽  
2015 ◽  
Vol 25 (10) ◽  
pp. 1127-1136 ◽  
Author(s):  
Salvatore Vaccarella ◽  
Luigino Dal Maso ◽  
Mathieu Laversanne ◽  
Freddie Bray ◽  
Martyn Plummer ◽  
...  
Keyword(s):  
Thyroid Cancer ◽  
Cancer Incidence ◽  
Population Based ◽  
Population Based Study ◽  
High Resource ◽  
The Impact ◽  
Diagnostic Changes ◽  
Thyroid Cancer Incidence
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