Assessment of 25-Hydroxy vitamin D level in pre- and postmenopausal women with euthyroid Hashimoto's thyroiditis

Author(s):  
Muge Bilge ◽  
Mine Adas ◽  
Aylia Yesilova ◽  
Aysen Helvaci
2016 ◽  
Vol 86 (1-2) ◽  
pp. 9-17 ◽  
Author(s):  
Bekir Ucan ◽  
Mustafa Sahin ◽  
Muyesser Sayki Arslan ◽  
Nujen Colak Bozkurt ◽  
Muhammed Kizilgul ◽  
...  

Abstract.The relationship between Hashimoto’s thyroiditis and vitamin D has been demonstrated in several studies. The aim of the present study was to evaluate vitamin D concentrations in patients with Hashimoto’s thyroiditis, the effect of vitamin D therapy on the course of disease, and to determine changes in thyroid autoantibody status and cardiovascular risk after vitamin D therapy. We included 75 patients with Hashimoto’s thyroiditis and 43 healthy individuals. Vitamin D deficiency is defined as a 25-hydroxy vitamin D (25(OH)D3) concentration less than 20ng/mL. Vitamin D deficient patients were given 50.000 units of 25(OH)D3 weekly for eight weeks in accordance with the Endocrine Society guidelines. All evaluations were repeated after 2 months of treatment. Patients with Hashimoto’s thyroiditis had significantly lower vitamin D concentrations compared with the controls (9.37±0.69 ng/mL vs 11.95±1.01 ng/mL, p < 0.05, respectively). Thyroid autoantibodies were significantly decreased by vitamin D replacement treatment in patients with euthyroid Hashimoto’s thyroiditis. Also, HDL cholesterol concentrations improved in the euthyroid Hashimoto group after treatment. The mean free thyroxine (fT4) concentrations were 0.89±0.02 ng/dL in patients with Hashimoto’s thyroiditis and 1.07±0.03 ng/dL in the healthy control group (p < 0.001). The mean thyroid volumes were 7.71±0.44 mL in patients with Hashimoto’s thyroiditis and 5.46±0.63 mL in the healthy control group (p < 0.01). Vitamin D deficiency is frequent in Hashimoto’s thyroiditis and treatment of patients with this condition with Vitamin D may slow down the course of development of hypothyroidism and also decrease cardiovascular risks in these patients. Vitamin D measurement and replacement may be critical in these patients.


Author(s):  
Hany William Z. Hanna ◽  
Cristiano Rizzo ◽  
Radwa Marawan Abdel Halim ◽  
Hemmat Elewa El Haddad ◽  
Randa Salam ◽  
...  

2016 ◽  
Vol 2 (2) ◽  
pp. 89-93
Author(s):  
Dithawut Khrutmuang ◽  
Krasean Panyakhamlerd ◽  
Sukanya Chatkittisilpa ◽  
Unnop Jaisamrarn ◽  
Nimit Taechakraichana

2015 ◽  
Vol 7 (2) ◽  
pp. 128-133 ◽  
Author(s):  
Olcay Evliyaoğlu ◽  
Manolya Acar ◽  
Bahar Özcabı ◽  
Ethem Erginöz ◽  
Feride Bucak ◽  
...  

2018 ◽  
Vol 55 (4) ◽  
pp. 261-268 ◽  
Author(s):  
Hakan Yavuzer ◽  
Selver Işık ◽  
Mahir Cengiz ◽  
İbrahim Murat Bolayırlı ◽  
Alper Döventaş ◽  
...  

2018 ◽  
Vol 8 (4) ◽  
pp. 165-170
Author(s):  
V.V. Povoroznyuk ◽  
A.S. Musiienko ◽  
N.I. Dzerovych ◽  
R.V. Povoroznyuk ◽  
O.S. Ivanyk

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