Incidental thyroid microcarcinoma diagnosed after total thyroidectomy for non-toxic solitary thyroid nodule: A 13-year single surgical-center experience (A retrospective study)

2018 ◽  
Author(s):  
Dimitrios Askitis ◽  
Eleni I Efremidou ◽  
Alexandra Giatromanolaki ◽  
Alexandros Polychronidis ◽  
Nikolaos Liratzopoulos
Keyword(s):  
Retrospective Study ◽  
Thyroid Nodule ◽  
Total Thyroidectomy ◽  
Thyroid Microcarcinoma ◽  
Solitary Thyroid Nodule

Controversies in Management of Thyroid Nodule

1995 ◽  
Vol 112 (5) ◽  
pp. P77-P78
Author(s):  
Ashok R. Shaha
Keyword(s):  
Thyroid Nodule ◽  
Total Thyroidectomy ◽  
Radioactive Iodine ◽  
Diagnostic Workup ◽  
Educational Objectives ◽  
Solitary Thyroid Nodule

Educational objectives: To become familiar with the diagnostic workup of a patient presenting with solitary thyroid nodule and to discuss the current controversies related to the treatment, including total versus less than total thyroidectomy and role of postoperative radioactive iodine.

scholarly journals Prevalence of Malignancy in Solitary Thyroid Nodule-A Retrospective Study

2021 ◽  
pp. 903-907
Author(s):  
A. Kavya ◽  
K. R. Manoj Prabu
Keyword(s):  
Retrospective Study ◽  
Thyroid Nodule ◽  
Histopathological Examination ◽  
Clinical Specimen ◽  
Preoperative Assessment ◽  
Cost Effective ◽  
Needle Aspiration ◽  
Vital Role ◽  
Female Ratio ◽  
Solitary Thyroid Nodule

Background: Solitary thyroid nodule is defined as discrete mass palpable in an otherwise apparently normal thyroid gland.  Solitary nodule is the common presentation of thyroid disorders. Objective: This study aimed to look into the prevalence of malignancy in clinico-radiologically detected solitary thyroid nodule and to correlate the findings in pre-operative fine needle aspiration cytology(FNAC) and post-operative histopathological examination(HPE). Materials and Methods: A retrospective study was carried out in our Institute for a period of 6 months using the data obtained between 2018-2020 of patients who were clinically and radiologically diagnosed as solitary thyroid nodule in the Department of General Surgery. Results: Out of 30 cases of clinically detected solitary thyroid nodule 7(23.3%)cases was found to be malignant. The mean age of presentation was 41.2 years with male female ratio of 1:9. 25(83.3%)cases was reported as benign nodules according to pre-operative FNAC out of these 2(6.6%)cases turned out to be malignant on post-operative histopathological examination. Conclusion: It is concluded that from the present study the prevalence of malignancy in clinically detected solitary thyroid nodule is 23.3%. FNAC being sensitive, cost effective and reliable tool in the preoperative assessment of solitary thyroid nodules and HPE in post operative evaluation of clinical specimen both playing a vital role in management of solitary thyroid nodule thus helping in early diagnosis and proper surgical intervention.

scholarly journals Choosing the best algorithm among five thyroid nodule ultrasound scores: from performance to cytology sparing—a single-center retrospective study in a large cohort

2021 ◽  
Author(s):  
Clotilde Sparano ◽  
Valentina Verdiani ◽  
Cinzia Pupilli ◽  
Giuliano Perigli ◽  
Benedetta Badii ◽  
...  
Keyword(s):  
Thyroid Nodule ◽  
Thyroid Nodules ◽  
Real Life ◽  
Scoring Systems ◽  
Diagnostic Procedures ◽  
Needle Aspiration ◽  
Common Disease ◽  
Single Center ◽  
Thyroid Microcarcinoma ◽  
Thyroid Malignancies

Abstract Objective Incidental diagnosis of thyroid nodules, and therefore of thyroid cancer, has definitely increased in recent years, but the mortality rate for thyroid malignancies remains very low. Within this landscape of overdiagnosis, several nodule ultrasound scores (NUS) have been proposed to reduce unnecessary diagnostic procedures. Our aim was to verify the suitability of five main NUS. Methods This single-center, retrospective, observational study analyzed a total number of 6474 valid cytologies. A full clinical and US description of the thyroid gland and nodules was performed. We retrospectively applied five available NUS: KTIRADS, ATA, AACE/ACE-AME, EUTIRADS, and ACRTIRADS. Thereafter, we calculated the sensitivity, specificity, PPV, and NPV, along with the number of possible fine-needle aspiration (FNA) sparing, according to each NUS algorithm and to clustering risk classes within three macro-groups (low, intermediate, and high risk). Results In a real-life setting of thyroid nodule management, available NUS scoring systems show good accuracy at ROC analysis (AUC up to 0.647) and higher NPV (up to 96%). The ability in FNA sparing ranges from 10 to 38% and reaches 44.2% of potential FNA economization in the low-risk macro-group. Considering our cohort, ACRTIRADS and AACE/ACE-AME scores provide the best compromise in terms of accuracy and spared cytology. Conclusions Despite several limitations, available NUS do appear to assist physicians in clinical practice. In the context of a common disease, such as thyroid nodules, higher accuracy and NPV are desirable NUS features. Further improvements in NUS sensitivity and specificity are attainable future goals to optimize nodule management. Key Points • Thyroid nodule ultrasound scores do assist clinicians in real practice. • Ultrasound scores reduce unnecessary diagnostic procedures, containing indolent thyroid microcarcinoma overdiagnosis. • The variable malignancy risk of the “indeterminate” category negatively influences score’s performance in real-life management of thyroid lesions.

scholarly journals Ultrasound Characterization of a Solitary Thyroid Nodule According to British Thyroid Association (BTA) - Derived Criteria: A Simple Test of Reliability on a Small Cohort

2021 ◽  
Vol 89 (6) ◽  
pp. 1063-1077
Author(s):  
LAMYA A. EISSA, M.D.; NOORALDEEN ALSAMAHI, M.S. ◽  
MOHAMED SAMY BARAKAT, M.D.; DINA ABDALLAH, M.D. ◽  
MUHAMMED MAHMOUD EL-SHAFEI, M.D.
Keyword(s):  
Thyroid Nodule ◽  
Simple Test ◽  
Solitary Thyroid Nodule ◽  
Small Cohort

scholarly journals Solitary thyroid nodule: an overview of one year study at a tertiary care hospital

2019 ◽  
Vol 6 (9) ◽  
pp. 3117
Author(s):  
Shyam Sundar Tandri ◽  
Ayathu V. S. Sai Mahesh
Keyword(s):  
Thyroid Nodule ◽  
Tertiary Care Hospital ◽  
Demographic Data ◽  
Tertiary Care ◽  
Common Finding ◽  
Clinical Approach ◽  
Care Hospital ◽  
Cross Sectional ◽  
Solitary Thyroid Nodule ◽  
One Year

Background: Thyroid nodules are a common finding in general practice. These nodules are either solitary or multinodular. In the present study thorough evaluation of all the cases presenting with a solitary thyroid nodule (STN) is done. The clear overview of prevalence of STN, associated risk factors, its distribution and its percentage of malignancy, clinic-pathological correlation and findings on ultra-sonogram.Methods: A one year cross sectional study at a tertiary care hospital was done after ethical committee approval. All cases of thyroid with solitary thyroid nodule were included and socio demographic data, clinical examination and USG data was noted. Thyroid hormone profile, FNAC and HPE was performed for every case enrolled and data was noted. The data was analyzed using SPSS version 22.Results: 350 cases were enrolled with 44.42% prevalence and 61.43% were females. Maximum age group was 31-40 years with swelling as the most common sign. 81.14% were euthyroid, 6.3% of cases had lymph node involvement. Micro calcification in 69.7% of nodules and 78.65 were solid. 40.3% of the STN were of colloid on FNAC and 6% were malignant. Malignancy on HPE was 14.6% and papillary carcinoma was the most commonest and follicular least.Conclusions: All cases of STN require a thorough clinical approach supported by ultra-sonogram, FNAC and detailed HPE after surgery for evaluation of benign and malignant lesions. Fine needle aspiration cytology has become an invaluable, minimally invasive and reliable tool in the preoperative assessment of patients with suspicion of malignancy.

Sign in / Sign up

Export Citation Format

Share Document