A Comparative Study on the Assessment of the Quality of Life by Older Cancer Patients and Caregivers and Assessment of Performance Status by Medical Staff

2015 ◽  
Vol 15 (3) ◽  
pp. 150 ◽  
Author(s):  
Kyoungwon Choi ◽  
Hoonsik Bae ◽  
Yeon Ok Lim ◽  
Ilsung Nam ◽  
Hyunsook Yoon ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Comparative Study ◽  
Cancer Patients ◽  
Medical Staff ◽  
Performance Status ◽  
Assessment Of Performance ◽  
Older Cancer Patients

A systematic review of the use and validation of health-related quality of life instruments in older cancer patients

2009 ◽  
Vol 45 (1) ◽  
pp. 19-32 ◽  
Author(s):  
Deborah Fitzsimmons ◽  
Jacqueline Gilbert ◽  
Frances Howse ◽  
Teresa Young ◽  
Juan-Ignacio Arrarras ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Systematic Review ◽  
Cancer Patients ◽  
Health Related Quality ◽  
Related Quality ◽  
Health Related ◽  
Older Cancer Patients ◽  
Quality Of Life Instruments

Epoetin beta treatment of chemotherapy induced anemia in cancer patients: Results of a large prospective cohort study

2007 ◽  
Vol 25 (18_suppl) ◽  
pp. 19582-19582 ◽  
Author(s):  
I. Ray-Coquard ◽  
J. Tourani ◽  
T. Facon ◽  
C. Haïoun ◽  
B. Audhuy ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Cancer Patients ◽  
Performance Status ◽  
Transferrin Saturation ◽  
Lymphocytic Leukemia ◽  
Routine Practice ◽  
Usual Practice ◽  
Endogenous Erythropoietin ◽  
Epoetin Beta

19582 Background: The efficacy of epoetin beta (E) is well documented in clinical trials in anemic cancer patients (pts). This study was conducted to assess E use, efficacy, safety and effect on quality of life in cancer pts, in usual practice. Methods: This prospective, multicenter, longitudinal, observational French study assessed a 4-month follow-up of informed consent cancer pts (including both solid tumors (ST) and hematological malignancies (H)) treated with E for chemotherapy-related anemia. Data were collected between January 2005 and March 2006. Results: Among 3100 pts enrolled by 423 specialists, 2810 were analysed. Pts’ characteristics were: mean age 63±13 yrs, male 50%, performance status 0 (13%), 1 (46%), =2 (41%). 74% of pts suffered from a ST and 26% from a H. The most frequent cancer types were lung (22%), breast (15%), non-Hodgkin lymphoma (12%), colon (9%), multiple myeloma (7%), ovary (7%), prostate (3%), head and neck (3%) and chronic lymphocytic leukemia (3%). The mean time from diagnosis to inclusion was 2 yrs. 52% of pts received their first line of chemotherapy, 25% their second one. 55% and 10% of ST and H pts received platinum based regimen, respectively. At inclusion, hemoglobin levels were distributed as follows: < 9 g/dl (ST 14%, H 32%), [9–11 [g/dl (ST 70%, H 56%), [11–13 [g/dl (ST 16%, H 11%). Regarding pre-treatment biological tests, endogenous erythropoietin rate was controlled for only 3% of pts (ST 1% and H 7%, median 37 IU/ml [0; 388]), ferritin was available for 15% of pts (ST 11% and H 28%), transferrin saturation for 12% of pts (ST 10% and H 17%) and reticulocytes for 11% of pts (ST 7% and H 24%). At initiation, pts received a median dose of 30000 U/week of E on a once weekly regimen schedule for 98% of pts. E was associated with iron supplementation in 49% and 13% of ST and H pts, and with blood transfusion in 5% and 15% of ST and H pts. Conclusion: These preliminary results describe baseline characteristics of cancer patients treated with epoetin beta. The study suggests very few biological controls before initiation of E in routine practice. Final analyses of hemoglobin evolution and quality of life will be presented. [Table: see text]

Effects of painting art therapy on quality of life and depression in cancer patients—A comparative study.

2014 ◽  
Vol 32 (15_suppl) ◽  
pp. e17583-e17583
Author(s):  
Hakan Sat Bozcuk ◽  
Keziban Ozcan ◽  
Cengiz Erdoğan ◽  
Hasan Mutlu ◽  
Hasan Senol Coskun
Keyword(s):  
Quality Of Life ◽  
Comparative Study ◽  
Cancer Patients ◽  
Art Therapy

Quality of life as a predictor of early death in older cancer patients: A prospective cohort study.

2018 ◽  
Vol 36 (15_suppl) ◽  
pp. e22017-e22017 ◽  
Author(s):  
Jurema Telles O Lima ◽  
Luiz Claudio Santos Thuler ◽  
Anke Bergmann ◽  
Barbara laffayette viana da Luz ◽  
Maria Julia Gonçalves Mello
Keyword(s):  
Quality Of Life ◽  
Cohort Study ◽  
Cancer Patients ◽  
Prospective Cohort Study ◽  
Prospective Cohort ◽  
Early Death ◽  
Older Cancer Patients

scholarly journals Validating an Instrument for Direct Patient Reporting of Distress and Chemotherapy-Related Toxicity among South African Cancer Patients

Cancers ◽  
2021 ◽  
Vol 14 (1) ◽  
pp. 95
Author(s):  
Charmaine L. Blanchard ◽  
Keletso Mmoledi ◽  
Michael H. Antoni ◽  
Georgia Demetriou ◽  
Maureen Joffe ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Construct Validity ◽  
Cancer Patients ◽  
South African ◽  
Pearson Correlation ◽  
Performance Status ◽  
Summary Score ◽  
Life Questionnaire ◽  
Patient Reported

Patient-reported outcome measures (PROM) for monitoring treatment toxicity improve quality of life (QoL) and clinical outcomes. However, no such PROMs exist for sub-Saharan African cancer patients. We aimed to validate the Patient Reported Symptoms-South Africa (PRS-SA) survey, a novel PROM for measuring distress and chemotherapy-related symptoms in South African cancer patients. We enrolled patients at the oncology clinic at Charlotte Maxeke Hospital, Johannesburg. At three separate visits, participants simultaneously completed the PRS-SA survey and several previously validated questionnaires. We constructed a receiver operator characteristics curve for distress levels predicting a Hospital Anxiety and Depression Scale (HADS) score ≥15. We evaluated construct validity for symptom items by comparing severity to the EORTC Core Quality of Life Questionnaire (QLQ-C30) summary score (Pearson correlation tests) and ECOG performance status (Mann–Whitney U tests). We assessed symptom item responsiveness by comparing change in severity to change in QLQ-C30 summary score and comparing standardized mean scores with negative, no, or positive change on the Global Impression of Change (GIC) questionnaire (Jockheere–Terpstra trend test). Overall, 196 participants with solid tumors completed instruments. A distress score of 4 had 82% sensitivity and 55% specificity for clinical depression/anxiety. All symptom items showed construct validity by association with either QLQ-C30 score or performance status (highest p = 0.03). All but cough showed responsiveness to change in QLQ-C30 score (highest p = 0.045). In South African cancer patients, the PRS-SA’s stress scale behaves similarly to the distress thermometer in other populations, and the symptom items demonstrated construct validity and responsiveness. Of note, 46% and 74% of participants who completed the PRS-SA in English or isiZulu, respectively, required assistance reading half or more of the instrument.

scholarly journals Effect of Chocolate on Older Cancer Patients in Palliative Care: A Randomised Controlled Study

2021 ◽  
Author(s):  
Josiane C. Vettori ◽  
Luanda G. da-Silva ◽  
Karina Pfrimer ◽  
Jordão-Junior Alceu A ◽  
Paulo Louzada-Junior ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Oxidative Stress ◽  
Palliative Care ◽  
Body Composition ◽  
Nutritional Status ◽  
Cancer Patients ◽  
Controlled Study ◽  
European Organization ◽  
Older Cancer Patients

Abstract Background Older advanced stage cancer patients, with changes in metabolic and nutritional status, represent an important demand for palliative care. The objective of the present study was to determine the effects of 4 weeks of chocolate consumption on the nutritional status, quality of life, body composition, oxidative stress and inflammaory activity of older cancer patients in palliative care. Methods Older cancer patients in palliative care with ambulatory monitoring were randomized to the following groups: control (CG, n = 15), intervention with 55% cocoa chocolate (IG1, n = 16) and intervention with white chocolate (IG2, n = 15) groups and evaluated before and after 4 weeks of treatment for nutritional status, food consumption, anthropometry, body composition, and laboratory parameters, and quality of life using the instrument of the European Organization for the Research and Treatment of Cancer. Results IG1 progressed with increased screening (p < 0.01) and nutritional (p = 0.04) scores on the Mini Nutritional Assessment tool. Anthropometry and body composition did not change. Regarding antioxidant capacity, reduced glutathione levels increased in IG2 (p = 0.04) and were higher than in IG1 (p < 0.01). Malondealdehyde levels were reduced in IG2 (p = 0.02) at the end of the study. Regarding quality of life, functionality improved in IG1, with a higher score in the functional domain (p = 0.03), and in the role functioning (p < 0.01) and in the social (p < 0.01) subdomains. Conclusions The consumption of chocolate with a greater cocoa content may contribute to the improvement of nutritional status and functionality among older cancer patients in palliative care. The consumption of white chocolate was associated with improved oxidative stress. Trial registration: ClinicalTrials.gov NCT04367493 - April 29, 2020. Retrospectively registered.

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