scholarly journals Seminoma in Undescended Intra Abdominal Testis: A Case Report

1970 ◽  
Vol 18 (2) ◽  
pp. 131-133 ◽  
Author(s):  
MM Haque ◽  
AB Siddique ◽  
ABMG Rabbani ◽  
MA Quasem ◽  
AKMG Rahman ◽  
...  
Keyword(s):  
Case Report ◽  
High Risk ◽  
Testicular Tumor ◽  
Early Age ◽  
Sexually Active ◽  
Lower Abdomen ◽  
Undescended Testes ◽  
Cryptorchid Testis ◽  
Risk Of Cancer ◽  
Abdominal Testis

A mass in the lower abdomen in a sexually active man with a cryptorchid testis strongly points towards the diagnosis of malignancy in the abdominal testis.1 The incidence of testicular tumor is 11 times more in inguinal testes and 50 times more in intra abdominal testes. 2 Normally, the testes, which are inside the abdomen during gestation, migrate into the scrotum by the time of birth. Occasionally, boys are born with testes that are still in the abdomen or in the groin, not having completed their journey to the scrotum. These undescended testes are at high risk of cancer and should be moved into the scrotum at an early age or removed entirely.   doi: 10.3329/taj.v18i2.3194 TAJ 2005; 18(2): 131-133

scholarly journals BLM Deficiency Is Not Associated with Sensitivity to Hydroxyurea-Induced Replication Stress

2010 ◽  
Vol 2010 ◽  
pp. 1-8 ◽  
Author(s):  
Kenza Lahkim Bennani-Belhaj ◽  
Géraldine Buhagiar-Labarchède ◽  
Nada Jmari ◽  
Rosine Onclercq-Delic ◽  
Mounira Amor-Guéret
Keyword(s):  
High Risk ◽  
Chromosomal Instability ◽  
Replication Fork ◽  
Replication Stress ◽  
Clonogenic Survival ◽  
Early Age ◽  
Replication Forks ◽  
Cellular Models ◽  
Bloom’S Syndrome ◽  
Risk Of Cancer

Bloom's syndrome (BS) displays one of the strongest known correlations between chromosomal instability and a high risk of cancer at an early age. BS cells combine a reduced average fork velocity with constitutive endogenous replication stress. However, the response of BS cells to replication stress induced by hydroxyurea (HU), which strongly slows the progression of replication forks, remains unclear due to publication of conflicting results. Using two different cellular models of BS, we showed that BLM deficiency is not associated with sensitivity to HU, in terms of clonogenic survival, DSB generation, and SCE induction. We suggest that surviving BLM-deficient cells are selected on the basis of their ability to deal with an endogenous replication stress induced by replication fork slowing, resulting in insensitivity to HU-induced replication stress.

scholarly journals Synchronous Seminoma in Abdominopelvic and Inguinal Testes: A Rare Presentation with Unusual Morphology

2017 ◽  
Vol 2017 ◽  
pp. 1-6
Author(s):  
Neha Prabhakar ◽  
Bhawna Sethi ◽  
Seema Nagger ◽  
Arun Saxena
Keyword(s):  
Testicular Cancer ◽  
Undescended Testis ◽  
Fetal Life ◽  
Third Trimester ◽  
Undescended Testes ◽  
Rare Presentation ◽  
The Third ◽  
Cryptorchid Testis ◽  
Abdominal Testis

The development of testes occurs in the abdomen during fetal life, after which they migrate into the scrotal sacs during the third trimester. During their descent, they may get arrested anywhere along the tract. Risk of testicular cancer is higher in patients with undescended testes, abdominal testis being more prone than inguinal. Seminoma is the commonest cancer in undescended testis. However, synchronous seminoma involving bilateral cryptorchid testis is rare. Present case is uncommon due to synchronous involvement of abdominopelvic and inguinal testes in extended age. It also exhibited unusual morphology with marked heterogeneity grossly as well as microscopically, instead of a common homogenous appearance.

scholarly journals Embryonal Carcinoma in Cryptorchid Abdominal Testis of an Infant

2015 ◽  
Vol 2015 ◽  
pp. 1-3
Author(s):  
Atia Zaka-ur-Rab ◽  
Zeeba Zaka-ur-Rab ◽  
Kafil Akhtar
Keyword(s):  
Embryonal Carcinoma ◽  
Undescended Testes ◽  
Testicular Tumors ◽  
Predisposing Factor ◽  
Primary Surgery ◽  
Cryptorchid Testis ◽  
Abdominal Testis

Cryptorchidism is a known predisposing factor for the development of testicular tumors in adults. Age of patient at the time of treatment of undescended testes has some bearing on the risk of neoplasia. Testicular neoplasia at the time of primary surgery for cryptorchidism has been reported rarely in prepubertal period. We report a case where embryonal carcinoma was detected in a cryptorchid testis of an infant.

A Community Based High Risk Register for Hearing Loss

1982 ◽  
Vol 47 (4) ◽  
pp. 373-375 ◽  
Author(s):  
James L. Fitch ◽  
Thomas F. Williams ◽  
Josephine E. Etienne
Keyword(s):  
Hearing Loss ◽  
System Identification ◽  
High Risk ◽  
Language Learning ◽  
Education Program ◽  
Communication System ◽  
Auditory Signal ◽  
Early Age ◽  
Community Based ◽  
Children With Hearing Loss

The critical need to identify children with hearing loss and provide treatment at the earliest possible age has become increasingly apparent in recent years (Northern & Downs, 1978). Reduction of the auditory signal during the critical language-learning period can severely limit the child's potential for developing a complete, effective communication system. Identification and treatment of children having handicapping conditions at an early age has gained impetus through the Handicapped Children's Early Education Program (HCEEP) projects funded by the Bureau of Education for the Handicapped (BEH).

Colorectal cancer knowledge and screening rates are lower than for breast cancer even in individuals at high risk of cancer

2001 ◽  
Vol 120 (5) ◽  
pp. A741-A741
Author(s):  
P ANG ◽  
D SCHRAG ◽  
K SCHNEIDER ◽  
K SHANNON ◽  
J JOHNSON ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Colorectal Cancer ◽  
High Risk ◽  
Cancer Knowledge ◽  
Risk Of Cancer

scholarly journals Abolishment of high-risk left lateral accessory pathway by myocardial infarction: a blessing in disguise? A case report

2021 ◽  
Vol 5 (2) ◽  
Author(s):  
Jim O’Brien ◽  
Nikola Kozhuharov ◽  
Shui Hao Chin ◽  
Mark Hall
Keyword(s):  
Atrial Fibrillation ◽  
Acute Coronary Syndrome ◽  
Case Report ◽  
High Risk ◽  
Coronary Sinus ◽  
Refractory Period ◽  
Accessory Pathway ◽  
Coronary Syndrome ◽  
Electrophysiology Study ◽  
Anomalous Coronary

Abstract Background Antegradely conducting left lateral accessory pathways are a risk for supraventricular tachycardias and pre-excited atrial fibrillation. Rarely, an anomalous coronary sinus can cause difficulty in locating the pathway. The left circumflex coronary artery and obtuse marginal branches supply the posterolateral left ventricle. We describe a case report of a high-risk accessory pathway associated with an anomalous coronary sinus which, between successive electrophysiology studies, was obliterated by a felicitous acute coronary syndrome in the left circumflex territory. Case summary A 49-year-old male with palpitations and manifest pre-excitation was referred for electrophysiology study. Initial study revealed a high-risk left lateral accessory pathway with antegrade effective refractory period of 240 ms and rapidly conducting pre-excited atrial fibrillation. The coronary sinus could not be cannulated to localize the pathway. Coronary angiography and cardiac computed tomography showed an anomalous coronary sinus emptying into the right atrial free wall and patent coronaries. While awaiting repeat electrophysiology study, the patient suffered an acute coronary syndrome with immediate loss of previously visible pre-excitation on electrocardiogram, and underwent stenting of an occluded marginal branch of the circumflex. Repeat electrophysiology study demonstrated a now low-risk accessory pathway (effective refractory period 390 ms). Since infarction, the patient’s palpitations have fully settled with all subsequent electrocardiograms devoid of manifest pre-excitation. Discussion Left lateral accessory pathways, which can associate with an anomalous coronary sinus, derive from tissue similar to normal ventricular myocardium and are vulnerable to ischaemic insults in the area subtended by the circumflex artery.

scholarly journals Fluvoxamine may prevent onset of psychosis: a case report of a patient at ultra-high risk of psychotic disorder

2011 ◽  
Vol 10 (1) ◽  
pp. 26 ◽  
Author(s):  
Shigenori Tadokoro ◽  
Nobuhisa Kanahara ◽  
Shuichi Kikuchi ◽  
Kenji Hashimoto ◽  
Iyo Masaomi
Keyword(s):  
Case Report ◽  
High Risk ◽  
Psychotic Disorder ◽  
Ultra High Risk

scholarly journals Formulating an anesthetic plan using a list of high-risk pregnant women on cloud-based business communication tools: a case report

2021 ◽  
Vol 7 (1) ◽  
Author(s):  
Junnosuke Kimura ◽  
Kento Kawamura ◽  
Manami Minoura ◽  
Ayako Hiramoto ◽  
Yoshifumi Suga ◽  
...  
Keyword(s):  
Case Report ◽  
High Risk ◽  
Cesarean Section ◽  
General Anesthesia ◽  
Pregnant Women ◽  
Cesarean Delivery ◽  
Business Communication ◽  
Communication Tools ◽  
Case Presentation ◽  
Emergency Cesarean

Abstract Background We report a case in which a list of high-risk pregnant women on cloud-based business communication tools was useful in formulating an anesthetic plan for unscheduled cesarean section. Case presentation A 37-year-old woman, who had been prescribed icosapentate for hypertriglyceridemia, received an antenatal anesthetic evaluation for possible cesarean delivery, and it was agreed that the anesthetic method for emergency cesarean section was general anesthesia if the surgery would take place within 7 days after the discontinuation of the drug, and regional anesthesia if it would take place any time later. Then this agreement was uploaded on the cloud-based business communication tools, and updated until she delivered her baby via unscheduled cesarean section. Conclusions A cloud-based business communication tools was useful in formulating an anesthesia plan for a patient undergoing a cesarean delivery. However, more discussion would be needed to utilize it in security.

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