High Altitude Illness

Key Points Individuals traveling to high altitudes (usually to ≥2,500 m) are at risk of developing high altitude illness (HAI), especially if ascending quickly.Acclimatization and slow ascent are the most effective ways to avoid HAI.Acetazolamide is prevention and treatment.High altitude illnesses typically respond to descent, oxygen therapy, or both.

2020 ◽  
Vol 27 (6) ◽  
Author(s):  
David R Shlim

Abstract Background Modern travel means that many travellers can arrive abruptly to high-altitude destinations without doing any trekking or climbing. Airports in high-altitude cities mean that travellers can go from sea level to over 3350–3960 m (11 000–13 000 feet) in a matter of hours, putting themselves at risk for high-altitude illness (HAI). Methods Acetazolamide has been shown to be an effective way to help prevent HAI on such itineraries. The risk of HAI on rapid arrival to altitudes over 3350 m (11 000 feet) has been shown to range from 35% to nearly 50%. The risk can be higher for high-altitude trekking. This risk is far higher than most travel medicine risks and is on a par with the risk of travellers’ diarrhea in high risk destinations. Result The use of prophylactic acetazolamide in a dosage of 125 mg every 12 h is highly effective at diminishing the risk of HAI. Conclusion Travel medicine practitioners should become comfortable with assessing the risk of HAI and determining when it is appropriate to offer acetazolamide prophylaxis to prevent HAI.


1977 ◽  
Vol 42 (5) ◽  
pp. 728-730 ◽  
Author(s):  
R. S. Hoon ◽  
S. C. Sharma ◽  
V. Balasubramanian ◽  
K. S. Chadha

In a preliminary pilot study we had reported a significant difference in urinary catecholamine excretion between symptomatic and asymptomatic individuals inducted to high altitude by air. The present study covers slower induction by road; 25 lowlanders ascended from 1,800 to 3,658 m in 50 h and 33 similar subjects covered the journey in 6 h. They were studied according to the protocal used in the initial study. None of the 58 subjects inducted by road developed symptoms of high-altitude illness. Their urinary catecholamine excretion remained normal during the 10 days' stay at high altitude. These findings lend support to our earlier contention that there might be a relationship between increased sympathoadrenal activity and high-altitude illnesses.


Author(s):  
Dean Jacobsen ◽  
Olivier Dangles

Chapter 2 presents the amazing variety of running waters, lakes, ponds, and wetlands found at high altitudes. These waterbodies are not equally distributed among the world’s high altitude places, but tend to be concentrated in certain areas, primarily determined by regional climate and topography. Thus, a large proportion of the world’s truly high altitude aquatic systems are found at lower latitudes, mostly in the tropics. The chapter presents general patterns in the geographical distribution of high altitude waters, and gives examples of some of the most extreme systems. High altitude aquatic systems and habitats cover a broad variety in dynamics and physical appearance. These differences may be related to, for example, water source (glacier-fed, rain-fed, or groundwater-fed streams), geological origin (e.g. glacial, volcanic, or tectonic lakes), or catchment slope and altitude (different types of peatland wetlands). This is exemplified and richly illustrated through numerous photos.


2004 ◽  
Vol 22 (2) ◽  
pp. 329-355 ◽  
Author(s):  
Scott A Gallagher ◽  
Peter H Hackett

Author(s):  
Flavia Wipplinger ◽  
Niels Holthof ◽  
Jasmin Lienert ◽  
Anastasia Budowski ◽  
Monika Brodmann Maeder ◽  
...  

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