Autoimmunity in Wiskott-Aldrich Syndrome: Risk Factors, Clinical Features, and Outcome in a Single-Center Cohort of 55 Patients

PEDIATRICS ◽  
2003 ◽  
Vol 111 (5) ◽  
pp. e622-e627 ◽  
Author(s):  
S. Dupuis-Girod ◽  
J. Medioni ◽  
E. Haddad ◽  
P. Quartier ◽  
M. Cavazzana-Calvo ◽  
...  
Keyword(s):  
Risk Factors ◽  
Clinical Features ◽  
Single Center ◽  
Wiskott Aldrich Syndrome

scholarly journals Clinical Features and Outcomes of 23 Patients with Wiskott- Aldrich Syndrome: A Single-Center Experience

2020 ◽  
Vol 37 (4) ◽  
pp. 271-281
Author(s):  
Şule Haskoloğlu ◽  
Ayşenur Öztürk ◽  
Gökcan Öztürk ◽  
Sevgi Kostel Bal ◽  
Candan İslamoğlu ◽  
...  
Keyword(s):  
Clinical Features ◽  
Single Center ◽  
Wiskott Aldrich Syndrome ◽  
Single Center Experience

scholarly journals CLINICAL FEATURES AND SENSITIZATION RISK FACTORS IN PATIENTS AWAITING KIDNEY TRANSPLANTATION: A SINGLE CENTER EXPERIENCE

2020 ◽  
Vol 104 (S3) ◽  
pp. S443-S444
Author(s):  
Siyar Erdogmus ◽  
Zeynep Kendi Celebi ◽  
Burak Sayin ◽  
F. Nurhan Ozdemir Acar ◽  
Emre Karakaya ◽  
...  
Keyword(s):  
Risk Factors ◽  
Kidney Transplantation ◽  
Clinical Features ◽  
Single Center ◽  
Single Center Experience

The clinical features of autoimmunity in 53 patients with Wiskott–Aldrich syndrome in China: a single-center study

2015 ◽  
Vol 174 (10) ◽  
pp. 1311-1318 ◽  
Author(s):  
Nan Chen ◽  
Zhi-Yong Zhang ◽  
Da-Wei Liu ◽  
Wei Liu ◽  
Xue-Mei Tang ◽  
...  
Keyword(s):  
Clinical Features ◽  
Single Center ◽  
Wiskott Aldrich Syndrome ◽  
Single Center Study ◽  
Center Study

scholarly journals Association between surgical volumes and hospital mortality in patients: a living donor liver transplantation single center experience

2021 ◽  
Vol 21 (1) ◽  
Author(s):  
Chia-En Hsieh ◽  
Ya-Lan Hsu ◽  
Kuo-Hua Lin ◽  
Ping-Yi Lin ◽  
Yu-Ju Hung ◽  
...  
Keyword(s):  
Risk Factors ◽  
Liver Transplantation ◽  
Blood Loss ◽  
Hospital Mortality ◽  
Clinical Features ◽  
Living Donor ◽  
Significant Risk ◽  
Surgical Volume ◽  
Single Center ◽  
Donor Age

Abstract Background Many factors cause hospital mortality (HM) after liver transplantation (LT). Methods We performed a retrospective research in a single center from October 2005 to June 2019. The study included 463 living donor LT patients. They were divided into a no-HM group (n = 433, 93.52%) and an HM group (n = 30, 6.48%). We used logistic regression analysis to determine how clinical features and surgical volume affected HM. We regrouped patients based on periods of surgical volume and analyzed the clinical features. Results Multivariate analysis revealed that donor age (OR = 1.050, 95% CI 1.011–1.091, p = 0.012), blood loss (OR = 1.000, 95% CI 1.000–1.000, p = 0.004), and annual surgical volumes being < 30 LTs (OR = 2.540, 95% CI 1.011–6.381, p = 0.047) were significant risk factors. A comparison of years based on surgical volume found that when the annual surgical volumes were at least 30 the recipient age (p = 0.023), donor age (p = 0.026), and ABO-incompatible operations (p < 0.001) were significantly higher and blood loss (p < 0.001), operative time (p < 0.001), intensive care unit days (p < 0.001), length of stay (p = 0.011), rate of re-operation (p < 0.001), and HM (p = 0.030) were significantly lower compared to when the annual surgical volumes were less than 30. Conclusions Donor age, blood loss and an annual surgical volume < 30 LTs were significant pre- and peri-operative risk factors. Hospital mortality and annual surgical volume were associated with statistically significant differences; surgical volume may impact quality of care and transplant outcomes.

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