PHONOCARDIOGRAPHIC DIFFERENTIATION OF THE MURMUR OF MITRAL INSUFFICIENCY FROM SOME COMMONLY HEARD ADVENTITIOUS SOUNDS IN CHILDHOOD

PEDIATRICS ◽  
1949 ◽  
Vol 3 (6) ◽  
pp. 845-853
Author(s):  
T. N. HARRIS ◽  
SIDNEY FRIEDMAN ◽  
CARL F. HAUB

Phonocardiographic tracings were recorded in children with known insufficiency of the mitral valve, children with a variety of systolic murmurs without blowing quality and children with no audible cardiac murmurs. The murmurs of valvular insufficiency produced tracings with a completely patternless and disorganized wave form. The other nonblowing murmurs all yielded tracings of uniform sine-wave character, regardless of their acoustic quality. Of these, the majority were "twanging-string" murmurs, the loudest of these with a distinct buzzing quality; the others were "snorting," "scraping" or "grating" in quality. Clinical observations indicated that these nonblowing murmurs were not indicative of cardiac disease. The murmurs of mitral insufficiency were significantly longer than the nonpathologic murmurs, but the latter showed, on the average, fully as great amplitude on the tracings. Physical and clinical implications of these findings are discussed.

2020 ◽  
Vol 91 (7) ◽  
pp. 592-596
Author(s):  
Quinn Dufurrena ◽  
Kazi Imran Ullah ◽  
Erin Taub ◽  
Connor Leszczuk ◽  
Sahar Ahmad

BACKGROUND: Remotely guided ultrasound (US) examinations carried out by nonmedical personnel (novices) have been shown to produce clinically useful examinations, at least in small pilot studies. Comparison of the quality of such exams to those carried out by trained medical professionals is lacking in the literature. This study compared the objective quality and clinical utility of cardiac and pulmonary US examinations carried out by novices and trained physicians.METHODS: Cardiac and pulmonary US examinations were carried out by novices under remote guidance by an US expert and independently by US trained physicians. Exams were blindly evaluated by US experts for both a task-based objective score as well as a subjective assessment of clinical utility.RESULTS: Participating in the study were 16 novices and 9 physicians. Novices took longer to complete the US exams (median 641.5 s vs. 256 s). For the objective component, novices scored higher in exams evaluating for pneumothorax (100% vs. 87.5%). For the subjective component, novices more often obtained clinically useful exams in the assessment of cardiac regional wall motion abnormalities (56.3% vs. 11.1%). No other comparisons yielded statistically significant differences between the two groups. Both groups had generally higher scores for pulmonary examinations compared to cardiac. There was variability in the quality of exams carried out by novices depending on their expert guide.CONCLUSION: Remotely guided novices are able to carry out cardiac and pulmonary US examinations with similar, if not better, technical proficiency and clinical utility as US trained physicians, though they take longer to do so.Dufurrena Q, Ullah KI, Taub E, Leszczuk C, Ahmad S. Feasibility and clinical implications of remotely guided ultrasound examinations. Aerosp Med Hum Perform. 2020; 91(7):592–596.


2013 ◽  
Vol 13 (02) ◽  
pp. 1340004
Author(s):  
APARNA NARENDRA BHALE ◽  
MANISH RATNAKAR JOSHI

Breast cancer is one of the major causes of death among women. If a cancer can be detected early, the options of treatment and the chances of total recovery will increase. From a woman's point of view, the procedure practiced (compression of breasts to record an image) to obtain a digital mammogram (DM) is exactly the same that is used to obtain a screen film mammogram (SFM). The quality of DM is undoubtedly better than SFM. However, obtaining DM is costlier and very few institutions can afford DM machines. According to the National Cancer Institute 92% of breast imaging centers in India do not have digital mammography machines and they depend on the conventional SFM. Hence in this context, one should answer "Can SFM be enhanced up to a level of DM?" In this paper, we discuss our experimental analysis in this regard. We applied elementary image enhancement techniques to obtain enhanced SFM. We performed the quality analysis of DM and enhanced SFM using standard metrics like PSNR and RMSE on more than 350 mammograms. We also used mean opinion score (MOS) analysis to evaluate enhanced SFMs. The results showed that the clarity of processed SFM is as good as DM. Furthermore, we analyzed the extent of radiation exposed during SFM and DM. We presented our literally findings and clinical observations.


2013 ◽  
Vol 17 (2) ◽  
pp. 174-185 ◽  
Author(s):  
R. Williams ◽  
C. W. Clark ◽  
D. Ponirakis ◽  
E. Ashe
Keyword(s):  

Surface ◽  
2018 ◽  
Vol 10(25) ◽  
pp. 37-50
Author(s):  
V. I. Grigoruk ◽  
◽  
V. I. Kanevskii ◽  
S. A. Kolenov ◽  
◽  
...  

Author(s):  
Margret Sibylle Engel ◽  
Júlio Otávio Herrmann ◽  
Paulo Henrique Trombetta Zannin

  The acoustic quality of classrooms has a strong influence on the teaching and learning process. This interference assessed using the impulsive technique to measure the rate of speech transmission (STI), reverberation time (RT) and sound definition (D50). These are the most relevant acoustic descriptors in the assessment of classrooms, where verbal exposure is the means of communication between teachers and students. The evaluation took place in two buildings of the Federal University of Paraná (UFPR), built in the 1960s and another in 2016. The measured values ​​of STI, provided in the classrooms' actual acoustic conditions, were used as an adjustment parameter for simulations made with the software ODEON. After carrying out the measurements and simulations, the dimensioning of improvements was possible. The acoustic simulations presented suggestions to qualify the quality of the classrooms' acoustic comfort, ensuring that teaching and learning to do not suffer losses due to the physical structure of the classrooms. The measured values ​​of STI, RT and D50 show that, in the old building, except for a single classroom that preserves the original ceiling that had a high sound absorption coefficient, it has reasonable values, below the ideal for classrooms, according to the IEC 60268-16 (2011) standard. The investigation showed that the rooms with a roof replaced by a PVC covering had a sharp drop in acoustic quality. The newest building has classrooms with proper acoustic comfort conditions.


Bioimpacts ◽  
2020 ◽  
Vol 10 (3) ◽  
pp. 137-138
Author(s):  
Jaleh Barar

COVID-19 pandemic has profoundly affected the lives of humans worldwide. We no longer experience the same quality of life and need to come up with effective solutions to combat the clinical implications. The vast knowledge about the pathways that regulate the virus entry and molecular signaling of the pathogenesis of coronavirus are the key factor for the development of de novo diagnostic/therapeutic strategies. Meanwhile, the emergence of nanotechnology, could offer enormous help in the battle against coronavirus. In this editorial, the role of molecular elements in the pathobiology of the disease and the significance of nanoscaled pharmaceuticals is highlighted.


2016 ◽  
Vol 26 (8) ◽  
pp. 1531-1536 ◽  
Author(s):  
Sarah Tabbutt ◽  
Nancy Ghanayem ◽  
Melvin C. Almodovar ◽  
John Charpie ◽  
Stephen J. Roth ◽  
...  

AbstractAs pediatric cardiac critical care becomes more sub-specialized it is reasonable to assume that dedicated units may provide a better infrastructure for improved multidisciplinary care, cardiac-specific patient safety initiatives, and dedicated training of fellows and residents. The knowledge base required to optimally manage pediatric patients with critical cardiac disease has evolved sufficiently to consider a standardized training curriculum and board certification for pediatric cardiac critical care. This strategy would potentially provide consistency of training and healthcare and improve quality of care and patient safety.


2021 ◽  
Vol 66 (1) ◽  
pp. 44-48
Author(s):  
I. Galstyan ◽  
M. Konchalovsky ◽  
M. Kozlova ◽  
V. Nugis

Purpose: On clinical examples to estimate a probable contribution of the postponed earlier external radiation of all body in the doses exceeding 1 Gy at development of multiple malignant neoplasms of different localization and a leukaemia. Material and methods: At 8 of 164 patients, it is long observed after the postponed acute radiation syndrome (ARS), multiple oncological diseases are revealed. Dynamics of consecutive forming of solid tumors at 2 patients and also malignant neoplasms and a myelodysplastic syndrome (MDS) with transformation in an acute leukamia at 1 patient is tracked. Observation duration – 31 years, 43 years and 32 years. Results: Availability of medical care to the patients who transferred ARS and high quality of its rendering at all stages (out-patient, stationary) allowed to reveal malignant neoplasms at early stages of development and to achieve an absolute recovery. However eventually at these patients development and other oncological diseases was observed. The given clinical observations allow to assume that at presented cases radiation acted on various stages of carcinogenesis, and its contribution to development of different oncological diseases in all patients was not identical. Conclusion: The analysis of clinical observations allows to assume that radiation contribution to genesis of various oncological diseases at the persons which underwent radiation in the doses causing development of ARS is various. Now in our country there are no approaches to quantitative assessment of a contribution of radiation effects to development of malignant neoplasms in each case. The patients who underwent acute single exposition in doses over 1 Gy have to be considered as having predisposition to development of multiple tumors in the remote terms. In this regard they for life need medical follow up for the purpose of early diagnostics and adequate treatment of the developing malignant neoplasms.


2021 ◽  
pp. 729-736
Author(s):  
Hoda Badr ◽  
Courtney Bitz

Cancer survivors experience significant physical, psychological, and social challenges that contribute to poor quality of life. Intimate partners provide critical care and support across the cancer continuum, but they report psychological distress, lack basic healthcare knowledge and skills, and experience increased tension and conflict in their relationships with survivors. Couple-based interventions hold great promise in cancer because they can simultaneously address survivor, partner, and relationship concerns. However, they are seldom implemented in healthcare settings as part of routine care. This chapter will therefore integrate what research has taught us about couples and cancer and what we have learned from couples in the clinical setting. We begin with an overview of challenges faced by couples across the cancer continuum, including biopsychosocial stressors. Next, we describe different perspectives that have shaped descriptive and intervention research on couples’ psychosocial adaptation to cancer. We conclude with clinical implications and directions for future research.


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