MORTALITY RISK OF EXCHANGE TRANSFUSION

PEDIATRICS ◽  
1968 ◽  
Vol 41 (4) ◽  
pp. 797-801
Author(s):  
Virginia V. Weldon ◽  
Gerald B. Odell

The exchange transfusions performed at The Johns Hopkins Hospital over a 6-year period have been reviewed. During this period there were 351 exchange transfusions performed on 232 infants with 11 deaths. The mortality rates in the present series are as low as any in the literature, even though the procedures have been carried out by a large group of pediatric house officers. The mortality risk in the premature infants was no greater than that for the full-term infant.

PEDIATRICS ◽  
1951 ◽  
Vol 8 (3) ◽  
pp. 431-434
Author(s):  
HEYWORTH N. SANFORD ◽  
J. HAROLD ROOT ◽  
R. H. GRAHAM

Chairman Sanford: Dr. Herman N. Bundesen, Commissioner of Health of Chicago, organized 12 years ago the "Chicago Premature Plan." This consists in registering all premature infants with the City Health Department within a few hours after birth. The premature infant who is born at home, or in a hospital that does not have adequate premature care, is transported in an oxygenated incubator ambulance to a hospital which specializes in such care. From 1936 to 1947 premature infant deaths in Chicago have been lowered 6½%. The full term infant death rate during the same period has been lowered about 3%. Inasmuch as the premature death rate has been lowered about double that of the full term infant rate, we believe this procedure has been the cause of reduction. In 1936 there were 47,000 live births in Chicago. In 1947 there were 82,000, or an increase of 80%. In this number the full term infants increased from 45% to 60%, whereas the premature infants increased from 2000 to over 5000, or about 140% increase of premature infants born in Chicago during the last 10 years. This adds a considerable increase to the number of infants for our available premature infants beds. Where formerly we planned 5 premature births to each 100 full term births, we now find that prematures have increased to 8 per 100 full term infants. Causes of prematurity are multiple births, toxemia, heart disease, syphilis, tuberculosis, infections, accidents, premature separation of the placenta and abnormalities of the reproduction tract. It is generally understood that there is a tendency for more premature births among the Negro race than the white race.


PEDIATRICS ◽  
1982 ◽  
Vol 69 (3) ◽  
pp. 381-382 ◽  
Author(s):  
Jerold F. Lucey

What to do for the low-birth-weight jaundiced neonate has been a subject of debate for 30 years. It is generally agreed that the "20 mg/100 ml level" for an exchange transfusion in a full-term infant with hemolytic disease, has been effective in avoiding deaths due to kernicterus and brain damage due to bilirubin neurotoxicity. It's not perfect, but it has been effective. This is amazing because the original studies, judged by modern standards, would not be acceptable today.1 Trouble first began when this concept was extended to jaundiced low-birth-weight infants. It was assumed that "the level" should be lower in smaller infants.


PEDIATRICS ◽  
1952 ◽  
Vol 10 (5) ◽  
pp. 533-537
Author(s):  
JULIA B. MACKENZIE

The serum of the premature infant contains material which inhibits bovine hyaluronidase. This inhibitor was found to be present to about the same degree in infants with and without retrolental fibroplasia and appeared to be unrelated to the severity of the disease. The level of the physiologic inhibitor of hyaluronidase found in the blood of the premature and full term infant is approximately of the same order of magnitude.


PEDIATRICS ◽  
1983 ◽  
Vol 72 (4) ◽  
pp. 560-562
Author(s):  
D. A. PICCOLI ◽  
S. PERLMAN ◽  
M. EPHROS

Several diseases can be transmitted to infants via transfusion. The risk of acquiring an infection via transfusion is greatly increased in sick premature infants because they receive frequent transfusions. The full-term infant is not fully competent immunologically,15 and the premature infant is even less able to deal with infection.6,15 Ideally, the transfusion of infected blood, especially into immunoincompetent recipients, should not occur. However, because screening for malaria in nonendemic regions is not practical, physicians caring for sick premature babies should consider transfusion-acquired malaria as a possible cause of illness, especially when there is no response to antibacterial therapy.


PEDIATRICS ◽  
1980 ◽  
Vol 65 (1) ◽  
pp. 163-164
Author(s):  
Robert G. Scherz

Nipples for dispensing milk to infants are sold throughout the United States and Canada in a diversity of retail outlets. The nipples have been designed in a variety of forms to include soft nipples for premature infants. The nipples for premature infants tend to be of thinner stock and more pliable than nipples designed for full-term infants. Although the nipples may well have labeling indicating that they have been prepared for premature infants, the adult who purchases them may not recognize that difference when they are displayed in an area that also provides standard nipples. The use of nipples designed for premature infants may present an aspiration hazard if they are used by a full-term infant.


2021 ◽  
Vol 42 (Supplement 1) ◽  
pp. S27-S29
Author(s):  
Wendy Si ◽  
Hoda Karbalivand ◽  
Tomas Havranek

PEDIATRICS ◽  
1968 ◽  
Vol 41 (3) ◽  
pp. 574-587 ◽  
Author(s):  
D. W. Thibeault ◽  
E. Poblete ◽  
P. A. M. Auld

Twenty-six premature and five full-term infants, ranging in birth weight from 860 to 4,040 gm and in age from 3 hours to 98 days, were the subjects of this study. Measurements of thoracic gas volume and determination of alveolar-arterial oxygen gradient and arterial-alveolar carbon dioxide gradient were performed. All infants showed a decrease in thoracic gas volume in the first days of life. The initial high thoracic gas volume is thought to be due to trapped gas. The ability to trap gas was demonstrated in a number of infants. In the full-term infant the decrease in thoracic gas volume is associated with improvement in lung function. In the premature infants the decrease in lung volume is associated with a persistently elevated alveolar-arterial oxygen gradient and in an inequality of perfusion and ventilation, as evidenced by the large arterial-alveolar carbon dioxide gradient. In a small group of infants increase in functional residual capacity produced by negative pressure around the chest resulted in a decrease in the carbon dioxide and oxygen gradients, indicating that the infant's lung volume is less than optimum. These observations characterize in physiological terms some of the respiratory difficulties in small premature infants.


PEDIATRICS ◽  
1973 ◽  
Vol 51 (2) ◽  
pp. 311-312
Author(s):  
L. Michael Fiengold

The case reported by Drs. Keidel and Feingold of Wilson Mikity Disease in a full-term infant indeed had meconium aspiration as a component. However, the baby went on to have oxygen dependency for at least a month following birth. This of course differs entirely from the syndrome of meconium aspiration. Moreover, the case was reviewed by Dr. Arnold Rudolph and Dr. Victor Mikity who read the x-rays personally. There is no doubt that the case report is valid and can clearly be differentiated from the course of the two infants that Dr. Cohen reported.


NeoReviews ◽  
2021 ◽  
Vol 22 (4) ◽  
pp. e275-e278
Author(s):  
Emman Dabaja ◽  
Deniz Altinok ◽  
Mallory O’Niel ◽  
Beena G. Sood

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