LEVEL OF HYALURONIDASE INHIBITOR IN THE SERUM OF PREMATURE INFANTS WITH RETROLENTAL FIBROPLASIA

PEDIATRICS ◽  
1952 ◽  
Vol 10 (5) ◽  
pp. 533-537
Author(s):  
JULIA B. MACKENZIE
Keyword(s):  
Premature Infant ◽  
Premature Infants ◽  
Term Infant ◽  
Full Term ◽  
Retrolental Fibroplasia ◽  
Full Term Infant ◽  
Hyaluronidase Inhibitor ◽  
Order Of Magnitude ◽  
Severity Of The Disease

The serum of the premature infant contains material which inhibits bovine hyaluronidase. This inhibitor was found to be present to about the same degree in infants with and without retrolental fibroplasia and appeared to be unrelated to the severity of the disease. The level of the physiologic inhibitor of hyaluronidase found in the blood of the premature and full term infant is approximately of the same order of magnitude.

Round Table Discussion

PEDIATRICS ◽  
1951 ◽  
Vol 8 (3) ◽  
pp. 431-434
Author(s):  
HEYWORTH N. SANFORD ◽  
J. HAROLD ROOT ◽  
R. H. GRAHAM
Keyword(s):  
Premature Infant ◽  
Premature Infants ◽  
Death Rate ◽  
Round Table ◽  
Term Infant ◽  
Full Term ◽  
Round Table Discussion ◽  
Premature Births ◽  
Term Infants ◽  
Full Term Infant

Chairman Sanford: Dr. Herman N. Bundesen, Commissioner of Health of Chicago, organized 12 years ago the "Chicago Premature Plan." This consists in registering all premature infants with the City Health Department within a few hours after birth. The premature infant who is born at home, or in a hospital that does not have adequate premature care, is transported in an oxygenated incubator ambulance to a hospital which specializes in such care. From 1936 to 1947 premature infant deaths in Chicago have been lowered 6½%. The full term infant death rate during the same period has been lowered about 3%. Inasmuch as the premature death rate has been lowered about double that of the full term infant rate, we believe this procedure has been the cause of reduction. In 1936 there were 47,000 live births in Chicago. In 1947 there were 82,000, or an increase of 80%. In this number the full term infants increased from 45% to 60%, whereas the premature infants increased from 2000 to over 5000, or about 140% increase of premature infants born in Chicago during the last 10 years. This adds a considerable increase to the number of infants for our available premature infants beds. Where formerly we planned 5 premature births to each 100 full term births, we now find that prematures have increased to 8 per 100 full term infants. Causes of prematurity are multiple births, toxemia, heart disease, syphilis, tuberculosis, infections, accidents, premature separation of the placenta and abnormalities of the reproduction tract. It is generally understood that there is a tendency for more premature births among the Negro race than the white race.

Transfusion-Acquired Plasmodium malariae Infection in Two Premature Infants

PEDIATRICS ◽  
1983 ◽  
Vol 72 (4) ◽  
pp. 560-562
Author(s):  
D. A. PICCOLI ◽  
S. PERLMAN ◽  
M. EPHROS
Keyword(s):  
Premature Infant ◽  
Premature Infants ◽  
Antibacterial Therapy ◽  
Plasmodium Malariae ◽  
Term Infant ◽  
Full Term ◽  
Infected Blood ◽  
Full Term Infant ◽  
Premature Babies ◽  
Possible Cause

Several diseases can be transmitted to infants via transfusion. The risk of acquiring an infection via transfusion is greatly increased in sick premature infants because they receive frequent transfusions. The full-term infant is not fully competent immunologically,15 and the premature infant is even less able to deal with infection.6,15 Ideally, the transfusion of infected blood, especially into immunoincompetent recipients, should not occur. However, because screening for malaria in nonendemic regions is not practical, physicians caring for sick premature babies should consider transfusion-acquired malaria as a possible cause of illness, especially when there is no response to antibacterial therapy.

THE POSTNATAL DEVELOPMENT OF THE COAGULATION SYSTEM IN THE PREMATURE INFANT

1987 ◽  
Author(s):  
M Andrew ◽  
B A Paes ◽  
R A Milner ◽  
P J Powers ◽  
M Johnston ◽  
...  
Keyword(s):  
Premature Infant ◽  
Postnatal Development ◽  
Premature Infants ◽  
Reference Values ◽  
Gestational Age ◽  
Term Infant ◽  
Full Term ◽  
Screening Tests ◽  
Coagulation System ◽  
Term Infants

A cohort study was performed to determine the postnatal development of the coagulation system in the “healthy” premature infant. Mothers were approached for consent and a total of 132 premature infants were entered into the study. The group consisted of 64 infants with gestational ages of 34-36 weeks (prem 1) and 68 infants whose gestational age was 33 weeks or less (prem 2). Demographic information and a 2 ml blood sample were obtained on days 1, 5, 30, 90, and 180. Plasma was fractionated and stored at −70°C for batch assaying of the following tests: screening tests, PT, APTT; factor assays (biologic (B)); fibrinogen, II, V, VII, VIII:C, IX, X, XI, XII, prekallikrein, high molecular weight kininogen, XIII (immunologic (I)); inhibitors (I), antithrombin III, aα2-antiplasmin, α2-macroglobulin, α-anti-trypsin, Cl esterase inhibitor, protein C, protein S, and the fibrinolytic system (B); plasminogen. We have previously reported an identical study for 118 full term infants. The large number of premature and full term infants studied at varying time points allowed us to determine the following: 1) coagulation tests vary with the gestational age and postnatal age of the infant; 2) each factor has a unique postnatal pattern of maturation; 3) near adult values are achieved by 6 months of age; 4) premature infants have a more rapid postnatal development of the coagulation system compared to the full term infant; and 5) the range of reference values for two age groups of premature infants has been established for each of the assays. These reference values will provide a basis for future investigation of specific hemorrhagic and thrombotic problems in the newborn infant.

STUDIES OF THE IMMUNOLOGY OF THE NEWBORN INFANT

PEDIATRICS ◽  
1954 ◽  
Vol 13 (4) ◽  
pp. 339-345
Author(s):  
JOSEPH DANCIS ◽  
HANS W. KUNZ
Keyword(s):  
Premature Infant ◽  
Term Infant ◽  
Full Term ◽  
In Vitro Test ◽  
Bacteriostatic Activity ◽  
Older Individuals ◽  
E Coli ◽  
Full Term Infant ◽  
The Poor

The bacteriostatic activity of the serum of infants was compared by an in vitro test with that of older children and adults in an attempt to explain the increased susceptibility to septicemia of the former. The serum of newborn infants at birth has a bacteriostatic activity against E. coli comparable to that of older individuals. This property is lost during the first weeks of life. It reappears in some infants in a few months and is usually present after one year of age. The bacteriostatic activity of premature infant serum follows closely that of the full term infant. The complement activity of 9 of 11 sera from premature infants fell within the range found in normal adult sera. Experiments using guinea pig serum as a source of complement also indicate that the poor bacteriostatic activity of premature infant serum is not the result of deficient complement ent activity. This is probably also true of the full term infant. Experiments with gamma globulin indicate that a deficiency in this serum fraction is at least partly responsible for the poor bacteriostatic performance of premature infant serum. Concurrent bacteriostatic tests with E. coli, Neisseria catarrhalis and Salmonella derby suggest that the ability to inhibit one organism is usually paralleled by the ability to inhibit the others. The possible nature of the bacteriostatic substances is discussed.

MORTALITY RISK OF EXCHANGE TRANSFUSION

PEDIATRICS ◽  
1968 ◽  
Vol 41 (4) ◽  
pp. 797-801
Author(s):  
Virginia V. Weldon ◽  
Gerald B. Odell
Keyword(s):  
Premature Infants ◽  
Mortality Risk ◽  
Exchange Transfusion ◽  
Mortality Rates ◽  
Term Infant ◽  
Full Term ◽  
Present Series ◽  
Johns Hopkins Hospital ◽  
Large Group ◽  
Full Term Infant

The exchange transfusions performed at The Johns Hopkins Hospital over a 6-year period have been reviewed. During this period there were 351 exchange transfusions performed on 232 infants with 11 deaths. The mortality rates in the present series are as low as any in the literature, even though the procedures have been carried out by a large group of pediatric house officers. The mortality risk in the premature infants was no greater than that for the full-term infant.

Premie Nipples: A Potential Aspiration Hazard

PEDIATRICS ◽  
1980 ◽  
Vol 65 (1) ◽  
pp. 163-164
Author(s):  
Robert G. Scherz
Keyword(s):  
United States ◽  
Premature Infants ◽  
The United States ◽  
Term Infant ◽  
Full Term ◽  
Term Infants ◽  
Full Term Infant ◽  
Retail Outlets

Nipples for dispensing milk to infants are sold throughout the United States and Canada in a diversity of retail outlets. The nipples have been designed in a variety of forms to include soft nipples for premature infants. The nipples for premature infants tend to be of thinner stock and more pliable than nipples designed for full-term infants. Although the nipples may well have labeling indicating that they have been prepared for premature infants, the adult who purchases them may not recognize that difference when they are displayed in an area that also provides standard nipples. The use of nipples designed for premature infants may present an aspiration hazard if they are used by a full-term infant.

Retrolental Fibroplasia in a Full-Term Infant

1975 ◽  
Vol 80 (1) ◽  
pp. 106-108 ◽  
Author(s):  
Marvin F. Kraushar ◽  
Rita G. Harper ◽  
Concepcion G. Sia
Keyword(s):  
Term Infant ◽  
Full Term ◽  
Retrolental Fibroplasia ◽  
Full Term Infant

Fatal Arrhythmia in a 2-day-old Full-term Infant

2021 ◽  
Vol 42 (Supplement 1) ◽  
pp. S27-S29
Author(s):  
Wendy Si ◽  
Hoda Karbalivand ◽  
Tomas Havranek
Keyword(s):  
Term Infant ◽  
Full Term ◽  
Full Term Infant ◽  
Fatal Arrhythmia

Dysphagia and Oral Feeding Problems in the Premature Infant

2002 ◽  
Vol 21 (2) ◽  
pp. 51-57 ◽  
Author(s):  
Martha Wilson Jones ◽  
Elaine Morgan ◽  
Jean Shelton
Keyword(s):  
Premature Infant ◽  
Premature Infants ◽  
Gestational Age ◽  
Term Infant ◽  
Oral Feeding ◽  
Feeding Disorders ◽  
Feeding Problems ◽  
The Past ◽  
Common Problems

FEEDING DISORDERS AND dysphagia are common problems seen in premature infants following their discharge from the NICU. A major factor in the growing incidence of these problems is the number of infants born and surviving between 23 and 25 weeks gestational age, which has increased dramatically over the past decade. These infants experience both a lengthier exposure to noxious oral stimuli and a longer time until they develop the suck/swallow coordination that makes oral feeding safe.1 Oral feeding is generally not offered before 32–34 weeks gestational age, when the preterm infant’s sucking pattern begins to resemble that of a term infant.2,3 Therefore, there may be an 8- to 9-week lag between birth and oral feedings in a 23- or 24-week gestational age infant.

Sign in / Sign up

Export Citation Format

Share Document