Prognosis with X-Chromosomal Abnormalities: Neoplastic Disease

PEDIATRICS ◽  
1972 ◽  
Vol 49 (1) ◽  
pp. 149-149
Author(s):  
Doris Bartuska ◽  
Linda Vardaro

The report of Eller, et al. on the prognosis in newborn infants with X-chromosomal abnormalities prompts this note. Because of our interest in cytogenetic factors in carcinogenesis, a routine buccal smear for sex chromatin is performed on all our patients with amenorrhea or irregular vaginal bleeding. Recently a 26-year-old woman with dysmenorrhea and irregular periods was seen. She had a mass arising from the cervix which was subsequently diagnosed as an unusual exophytic type of squamous cell carcinoma.

1979 ◽  
Vol 87 (6) ◽  
pp. 707-716 ◽  
Author(s):  
Edwin A. Cortez ◽  
Douglas E. Mattox ◽  
G. Richard Holt ◽  
George A. Gates

Unilateral tonsillar enlargement may result from infection, chronic inflammatory response, or neoplasm. Neoplasms that commonly produce a unilaterally enlarged tonsil include lymphomas (lymphocytic and histiocytic types) and squamous cell carcinomas. Rarer tumors include extramedullary plasmacytomas, Hodgkin's disease, leukemia, and metastatic neoplasms. Sixteen cases of unilateral tonsillar enlargement owing to causes other than squamous cell carcinoma are reviewed. When examining a patient with unilateral tonsillar enlargement, diagnosis of a neoplastic disease must be considered.


2017 ◽  
Vol 18 (4) ◽  
pp. 361-363
Author(s):  
Vesna Milicic ◽  
Ana Ravic-Nikolic ◽  
Bojana Jovovic-Dagovic ◽  
Stevan Stojanovic ◽  
Slobodanka Lj. Mitrovic

AbstractPustular psoriasis is an uncommon form of psoriasis consisting of widespread pustules on an erythematous background. Very rarely pustular psoriasis represent a paraneoplastic dermatosis. In this report we describe a case of generalized pustular psoriasis (GPP) associated with advanced, inoperable, metastatic squamous cell carcinoma of the hypopharynx. We suggest that physicians should be alert for the worsening of existing psoriasis or formation of novel psoriasiform eruptions and should undertake clinical evaluation of possible neoplastic disease.


Author(s):  
M. A. Usman ◽  
S. A. Otene

The purpose of this study was to evaluate the socio-demographic and clinicopathological features of patients with cervical cancer seen in a comprehensive cancer center in North-western Nigeria. It was a six years retrospective study of patients with cervical cancer treated in the Department of Radiotherapy and Oncology, UDUTH, Sokoto. Data was obtained from the patients’ case notes using a semi-structured data extraction form. A total of 220 cases were reviewed for patients whose mean age was 49.9 years (SD ± 11.9); with the age range of 24-87 years. Results show that squamous cell carcinoma was the most common histological type seen in 182(82.7%) of the patients, followed by adenocarcinoma 22(10%) and clear cell carcinoma 9(4.1%). Vaginal bleeding 110(50%), foul-smelling vaginal discharge103 (46.8%), fatigue 67(30.5%), lower abdominal pain 65(20.5%) and weight loss 30(13.6%) were the commonest clinical features. 176(80%) patients presented late stages (IIB – IVB) of cervical cancer. Concluding, most of the women with cervical cancer presented with features of vaginal bleeding or foul-smelling vaginal discharge, weight loss, fatigue and lower abdominal pain, with commonest histological categorization being squamous cell carcinoma. Late presentation of the disease was obviously observed in most of the cases diagnosed. The clinical features of cervical cancer identified in the cases reviewed are indicators of advanced disease. Thus, it is imperative that advocacy for cervical cancer screening should be stepped up in order to ensure early detection and prevent the progression of the disease to advanced stages.


1995 ◽  
Vol 31 (5) ◽  
pp. 373-378 ◽  
Author(s):  
KS Rogers ◽  
RG Helman ◽  
MA Walker

Squamous cell carcinoma of the nasal planum was diagnosed in eight dogs between March 1988 and January 1994. Epistaxis, sneezing, and ulceration or swelling of the nasal planum were the most common presenting complaints. Although no evidence of metastasis was identified, the primary tumor in all cases was locally invasive with extensive involvement of underlying tissues. Advanced imaging procedures performed in three cases indicated that physical examination may underestimate the local extent of the neoplasm. Euthanasia was performed in six cases due to progressive neoplastic disease with worsening epistaxis and sneezing; the mean survival time in these cases was 5.4 months.


1987 ◽  
Vol 80 (9) ◽  
pp. 587-588 ◽  
Author(s):  
G C Raju ◽  
E N Barton ◽  
D Marchack ◽  
V Naraynsingh

Hypercalcaemia associated with neoplastic disease is well recognized1,2, and has potentially serious consequences if not corrected promptly. We report a case of primary squamous cell carcinoma of the stomach associated with hypercalcaemia, an association that seems not to have been reported previously.


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