KIDNEY FUNCTION IN YOUNG INFANTS

PEDIATRICS ◽  
1950 ◽  
Vol 5 (2) ◽  
pp. 171-179
Author(s):  
HENRY L. BARNETT
Keyword(s):  
New York ◽  
Kidney Function ◽  
Public Health Service ◽  
Medical Center ◽  
Heart Association ◽  
Primary Role ◽  
Young Infants ◽  
New York Heart Association ◽  
Clinical Problems

IT IS with gratitude that I accept this second E. Mead Johnson Award, being fully aware of the honor it brings to all of us who have shared in the work. The progress of the work has been stimulated by the encouragement and guidance given previously by Dr. Alexis F. Hartmann in St. Louis and, more recently, by Dr. Samuel Z. Levine in New York. I also wish to thank the doctors, nurses, technicians, secretaries and laboratory helpers who have actively participated and especially Miss Helen McNamara who makes the editorial "we" a reality. The nature of our studies required substantial financial support and we wish to express appreciation to the U. S. Public Health Service and the New York Heart Association for supplementing the excellent facilities for research at the New York Hospital-Cornell Medical Center. It is the purpose of this paper to consider the development and present status of our knowledge of kidney function in young infants and to indicate some of its application to clinical problems. This knowledge is understandably incomplete because it is only during the last 10 years that the precise technics of kidney physiologists have been applied to the study of kidney function in young infants. The primary role of the kidneys in regulating the composition and volume of body fluids had been established earlier by an important series of observations, utilizing the technics of water and electrolyte balances. In many of these earlier observations there were already indications of an underdeveloped kidney function in young infants.

Determinants of Self-Care in Patients With Heart Failure: Observations From a Developing Country in the Middle East

2019 ◽  
Vol 31 (3) ◽  
pp. 294-303 ◽  
Author(s):  
Angela Massouh ◽  
Huda Abu Saad Huijer ◽  
Paula Meek ◽  
Hadi Skouri
Keyword(s):  
Heart Failure ◽  
Social Support ◽  
New York ◽  
Care Management ◽  
Medical Center ◽  
Self Care ◽  
Heart Association ◽  
Caregiver Support ◽  
Patients With Heart Failure ◽  
New York Heart Association

Introduction: Self-care is recognized as a means for improving outcomes of heart failure (HF), yet studies have not addressed what predicts successful self-care in collectivist cultures like Lebanon. Methodology: Self-care was measured, using the Arabic Self-Care of HF index, in 100 participants with HF (76% males; mean age 67.59) recruited from a tertiary medical center. Results: Self-care was suboptimal, with mean scores of 67.26, 66.96, and 69.5 for self-care maintenance, management, and confidence. Better HF knowledge, social support, and self-care confidence and lower New York Heart Association score predicted better self-care maintenance. Better knowledge, social support, and self-care maintenance, no recent hospitalization, and being unemployed predicted better self-care confidence. Better self-care confidence, maintenance, and HF knowledge predicted better self-care management. Discussion: HF self-care in Lebanon is suboptimal. Nurses need to identify facilitators of and barriers to self-care particular to this population. Interventions targeting HF knowledge, confidence, and caregiver support are expected to improve self-care in Lebanese patients.

scholarly journals Evaluation of serum neutrophil gelatinase–associated lipocalin as a novel biomarker of cardiorenal syndrome in dogs

2018 ◽  
Vol 30 (3) ◽  
pp. 386-391 ◽  
Author(s):  
Han-Byeol Jung ◽  
Min-Hee Kang ◽  
Hee-Myung Park
Keyword(s):  
New York ◽  
Troponin I ◽  
Heart Association ◽  
Cardiorenal Syndrome ◽  
Neutrophil Gelatinase Associated Lipocalin ◽  
Patients With Heart Failure ◽  
New York Heart Association ◽  
Neutrophil Gelatinase

Worsening renal function and azotemia in patients with heart failure (HF) are strongly associated with disease severity and poor prognosis. Increasing interest in this correlation led to the description and classification of cardiorenal syndrome (CRS). We evaluated the role of neutrophil gelatinase–associated lipocalin (NGAL) in the early detection of CRS in dogs with HF. Ten healthy dogs and 31 dogs admitted with HF were included in our study. NGAL and troponin-I were measured on samples collected on the day of admission; creatinine was measured on admission and again on day 7. The CRS group was defined as subsequently developing renal azotemia. Of 31 dogs with HF, 20 were included in the HF group, and 11 were included in the CRS group. The admission NGAL concentrations of the CRS group were significantly higher than those of other groups ( p < 0.001). The severity of HF evaluation based on the modified New York Heart Association classification showed significant correlation with NGAL ( p < 0.001) and troponin-I ( p = 0.009) concentration. However, only serum NGAL concentration at admission was significantly associated with the development of CRS in dogs with HF ( p = 0.021). The admission serum NGAL ≥ 16.0 ng/mL (optimal cutoff value) had a sensitivity of 90.9% and specificity of 90.0% in predicting the development of CRS.

scholarly journals Effects of Transapical Transcatheter Mitral Valve Implantation

2021 ◽  
Vol 8 ◽  
Author(s):  
Ming-Chon Hsiung ◽  
Wei-Hsian Yin ◽  
Yung-Tsai Lee ◽  
Tien-Ping Tsao ◽  
Kuo-Chen Lee ◽  
...  
Keyword(s):  
New York ◽  
Mitral Valve ◽  
Clinical Outcomes ◽  
Medical Center ◽  
Heart Association ◽  
Total Procedure Time ◽  
Significant Difference ◽  
New York Heart Association ◽  
Valve Implantation ◽  
Skin To Skin

Purpose: In this study, transapical transcatheter mitral valve-in-valve implantation (TAMVI) was compared with surgical redo mitral valve replacement (SRMVR) in terms of clinical outcomes.Methods: We retrospectively identified patients with degenerated mitral bioprosthesis or failed annuloplasty rings who underwent redo SRMVR or TAMVI at our medical center. Clinical outcomes were based on echocardiography results.Results: We retrospectively identified patients with symptomatic mitral bioprosthetic valve dysfunction (n = 58) and failed annuloplasty rings (n = 14) who underwent redo SRMVR (n = 36) or TAMVI (n = 36). The Society of Thoracic Surgeons Predicted Risk of Mortality scores were higher in the TAMVI group (median: 9.52) than in the SRMVR group (median: 5.59) (p-value = 0.02). TAMVI patients were more severe in New York Heart Association (p-value = 0.04). The total procedure time (skin to skin) and length of stay after procedures were significantly shorter in the TAMVI group, and no significant difference in mortality was noted after adjustment for confounding factors (p-value = 0.11). The overall mean mitral valve pressure gradient was lower in the TAMVI group than in the SRMVR group at 24 months (p &lt; 0.01). Both groups presented a decrease in the severity of mitral and tricuspid regurgitation at 3–24 months.Conclusions: In conclusion, the statistical analysis is still not robust enough to make a claim that TAMVI is an appropriate alternative. The outcome of the patient appears only to be related to the patient's pre-operative STS score. Additional multi-center, longitudinal studies are warranted to adequately assess the effect of TAMVI.

Illness Perception and Its Changes During Six Months After Cardiac Rehabilitation

2019 ◽  
Vol 26 (3) ◽  
pp. 90-100
Author(s):  
Justė Lukoševičiūtė ◽  
Kastytis Šmigelskas
Keyword(s):  
New York ◽  
Social Factors ◽  
Nyha Class ◽  
Illness Perception ◽  
Heart Association ◽  
Class Iii ◽  
Cognitive Representations ◽  
Coronary Syndrome ◽  
Type D ◽  
New York Heart Association

Abstract. Illness perception is a concept that reflects patients' emotional and cognitive representations of disease. This study assessed the illness perception change during 6 months in 195 patients (33% women and 67% men) with acute coronary syndrome, taking into account the biological, psychological, and social factors. At baseline, more threatening illness perception was observed in women, persons aged 65 years or more, with poorer functional capacity (New York Heart Association [NYHA] class III or IV) and comorbidities ( p < .05). Type D personality was the only independent factor related to more threatening illness perception (βs = 0.207, p = .006). At follow-up it was found that only self-reported cardiovascular impairment plays the role in illness perception change (βs = 0.544, p < .001): patients without impairment reported decreasing threats of illness, while the ones with it had a similar perception of threat like at baseline. Other biological, psychological, and social factors were partly associated with illness perception after an acute cardiac event but not with perception change after 6 months.

scholarly journals Lockdown, slow down: impact of the COVID-19 pandemic on physical activity—an observational study

Open Heart ◽  
2021 ◽  
Vol 8 (1) ◽  
pp. e001600
Author(s):  
Joanne Kathryn Taylor ◽  
Haarith Ndiaye ◽  
Matthew Daniels ◽  
Fozia Ahmed
Keyword(s):  
Physical Activity ◽  
New York ◽  
Heart Association ◽  
Evaluation Study ◽  
Activity Data ◽  
Cardiac Devices ◽  
Significant Difference ◽  
New York Heart Association ◽  
Using Data ◽  
The Uk

AimsIn response to the COVID-19 pandemic, the UK was placed under strict lockdown measures on 23 March 2020. The aim of this study was to quantify the effects on physical activity (PA) levels using data from the prospective Triage-HF Plus Evaluation study.MethodsThis study represents a cohort of adult patients with implanted cardiac devices capable of measuring activity by embedded accelerometery via a remote monitoring platform. Activity data were available for the 4 weeks pre-implementation and post implementation of ‘stay at home’ lockdown measures in the form of ‘minutes active per day’ (min/day).ResultsData were analysed for 311 patients (77.2% men, mean age 68.8, frailty 55.9%. 92.2% established heart failure (HF) diagnosis, of these 51.2% New York Heart Association II), with comorbidities representative of a real-world cohort.Post-lockdown, a significant reduction in median PA equating to 20.8 active min/day was seen. The reduction was uniform with a slightly more pronounced drop in PA for women, but no statistically significant difference with respect to age, body mass index, frailty or device type. Activity dropped in the immediate 2-week period post-lockdown, but steadily returned thereafter. Median activity week 4 weeks post-lockdown remained significantly lower than 4 weeks pre-lockdown (p≤0.001).ConclusionsIn a population of predominantly HF patients with cardiac devices, activity reduced by approximately 20 min active per day in the immediate aftermath of strict COVID-19 lockdown measures.Trial registration numberNCT04177199.

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