Soy-Protein Formulas: Recommendations for Use in Infant Feeding

PEDIATRICS ◽  
1983 ◽  
Vol 72 (3) ◽  
pp. 359-363
Author(s):  
Keyword(s):  
Soy Protein ◽  
Cow’S Milk ◽  
Infant Formulas ◽  
Human Infants ◽  
Term Infants ◽  
Cow's Milk ◽  
Clear Cut ◽  
Critical Issues ◽  
Milk Substitute

Many infant formulas are available as alternatives to breast-feeding. These formulas are necessary and valuable resources in the nutriture of infants, but it is important to evaluate their use and efficacy periodically. Soybean preparations were suggested as a milk substitute by Hill and Stuart1 in 1929. Since then, the use of these products has expanded appreciably, and they are used for an estimated 10% to 15% of all formula-fed infants. This increase in use has prompted examination of the following critical issues about the indications for use of soy-protein formulas in infants. (1) Are soy-protein formulas an adequate nutritional substitute for cow's milk-based formulas in full-term infants? (2) Is it appropriate to recommend soy-protein formulas to provide a lactose-free formula, or are there better alternatives? (3) Are soy-protein formulas ever indicated for use in premature infants? (4) What is the evidence for and against the use of soy-protein formulas in the management of cow's milkprotein allergy? (5) What is the role of soy-protein formulas in prophylaxis of allergic disease? (6) What is the evidence for and against the use of soy-protein formulas in the management of "colic"? Examination of these issues will hopefully, provide a more clear-cut basis for decisions regarding the use of soy-protein formulas and updated recommendations for the role of soy-protein formulas in feeding human infants. COMPOSITION OF SOY-PROTEIN FORMULAS Soy-protein formulas, although different in carbohydrate and protein source, are similar in composition to cow's milk-protein formulas following the American Academy of Pediatrics, Committee on Nutrition, 1976 recommendations for nutrient levels in infant formulas.2

scholarly journals Got Mylk? The Emerging Role of Australian Plant-Based Milk Alternatives as A Cow’s Milk Substitute

Nutrients ◽  
2020 ◽  
Vol 12 (5) ◽  
pp. 1254 ◽  
Author(s):  
Yianna Y. Zhang ◽  
Jaimee Hughes ◽  
Sara Grafenauer
Keyword(s):  
Compositional Data ◽  
Calcium Content ◽  
Food Composition ◽  
Cow’S Milk ◽  
Cross Sectional Survey ◽  
Cross Sectional ◽  
Cow's Milk ◽  
Food Retailers ◽  
Milk Substitute

Growing ethical, environmental and health concerns have encouraged demand for novel plant-based milk alternatives, yet it remains nebulous whether these products are nutritionally adequate as cow’s milk replacements. The aim of this study was to conduct a cross-sectional survey of plant-based milk alternatives available in major Australian supermarkets and selected niche food retailers from November 2019 to January 2020 and assess two dietary scenarios (adolescents and older women) where dairy serves were substituted for plant-based alternatives against Australian Estimated Average Requirements (EAR). We collected compositional data from nutrition panels in juxtaposition with derivatives from the Australian Food Composition database, with a total of 115 products, including tree nuts and seeds (n = 48), legumes (n = 27), coconut (n = 10), grains (n = 19) and mixed sources (n = 10). Just over 50% of products were fortified, but only 1/3 contained similar calcium content to cow’s milk. Indiscriminate substitutions might reduce intakes of protein and micronutrients, particularly vitamin A, B2, B12, iodine and zinc, and lead to reductions >50% of the EARs for protein, zinc and calcium in the chosen dietary scenarios. To avoid unintended dietary outcomes, it is vital that consumers make pragmatic decisions regarding dietary replacements for cow’s milk.

scholarly journals Soy protein sensitization in cow’s milk allergy patients

2007 ◽  
Vol 47 (2) ◽  
pp. 78 ◽  
Author(s):  
Dina Muktiarti ◽  
Zakiudin Munasir ◽  
Alan R. Tumbelaka
Keyword(s):  
Soy Protein ◽  
Cow’S Milk Allergy ◽  
Cow’S Milk ◽  
Milk Allergy ◽  
Cow's Milk ◽  
Cow's Milk Allergy ◽  
Milk Substitute ◽  
History Of ◽  
Ige Mediated ◽  
Protein Sensitization

Background The management of cow’s milk allergy (CMA) isavoidance of cow’s milk as strictly as possible. Extensive hydrolyzedprotein and amino acid based formulas are recommended dietaryproducts for treatment of CMA. However, they have somedisadvantages, such as bitter taste and high cost. Alternativeprotein sources from vegetable proteins, such as soy, can be usedas milk-substitute. Previous studies showed the prevalence of soyallergy in CMA patients in Western countries ranged between 0to 63%, but the prevalence in Asia was not greater than 20% andno data about this prevalence in Indonesia.Objectives To determine the proportion of soy proteinsensitization in CMA patients and characteristics of CMA patientswho were sensitized to soy protein.Methods Fifty seven CMA patients who consumed soy proteinwere taken their blood sample to examine the soy-specific IgE.Results From 57 CMA patients, we found only 18% of patientswho were sensitized to soy protein. Seven out of ten CMA patientswho were sensitized to soy protein were under 12 months old.Atopic dermatitis was the most frequent clinical manifestation(8/10) and all of them had family history of atopic diseases. Soysensitization in IgE-mediated and non-IgE mediated CMA were6/10 and 4/10, respectively.Conclusions Proportion of soy sensitization in CMA patients inthis study was 18%. Soy protein can be used as an alternative forcow’s milk substitute in CMA patients.

scholarly journals The Glycemic Response to Infant Formulas: a Randomized Clinical Trial

2021 ◽  
Author(s):  
Adi Anafy ◽  
Hadar Moran-Lev ◽  
Niva Shapira ◽  
Meital Priel ◽  
Asaf Oren ◽  
...  
Keyword(s):  
Soy Protein ◽  
Glycemic Index ◽  
Milk Protein ◽  
Biological Significance ◽  
Cow’S Milk ◽  
Infant Formulas ◽  
Cow's Milk ◽  
Glucose Levels ◽  
Significant Difference ◽  
Cow’S Milk Protein

Abstract Objectives: Commercial infant formulas attempt to imitate the unique composition of human milk, which contributes to its distinctive influence on glycemic and insulinemic responses. However, lactose-free and milk protein-free formulas are often recommended due to medical reasons or chosen due to personal preferences (e.g., veganism). The aim of this study was to determine the glycemic and insulinemic indices of a variety of infant formulas.Methods: We conducted a three-arm, randomized, double-blind, crossover study. The participants were healthy adult volunteers aged 25-40 years. Each participant randomly drank three commercially available infant formulas (cow's milk protein-based ["standard"], soy protein-based, and lactose-free). Glycemic and insulinemic responses and glucose and insulin blood levels were determined and compared between the three formulas. Results: Twenty subjects were enrolled (11 females/9 males, mean age 32.8 ± 2.9 years). No significant difference was found in the glycemic index between the three formulas (21.5, 29.1, and 21.5 for the standard, soy protein-based, and lactose-free formulas, respectively, p = 0.21). However, maximal glucose levels were significantly higher for the soy protein-based formula compared to both the standard and lactose-free formulas (111.5 mg/dL compared to 101.8 mg/dL and 105.8 mg/dL, respectively, p = 0.001).Conclusion: A cow's milk protein-based formula, a lactose-free formula, and a soy protein-based formula elicited similar glycemic index. However, soy protein-based formula produced a significantly higher increase in postprandial glucose levels. The implication and the biological significance of these results has yet to be determined.

Cow's Milk Formula as a Cause of Infantile Colic: A Double-Blind Study

PEDIATRICS ◽  
1982 ◽  
Vol 70 (1) ◽  
pp. 7-10 ◽  
Author(s):  
Lasse Lothe ◽  
Tor Lindberg ◽  
Irene Jakobsson
Keyword(s):  
Gastrointestinal Symptoms ◽  
Dietary Treatment ◽  
Blind Study ◽  
Cow’S Milk ◽  
Milk Formula ◽  
Double Blind Study ◽  
Infantile Colic ◽  
Double Blind ◽  
Cow's Milk

The role of cow's milk in infantile colic in formula-fed infants was estimated in a double-blind study. Sixty colicky infants were given a cow's milk-containing formula (Enfamil) and a cow's milk-free formula based on soy (ProSobee). Eleven infants (18%) were free of symptoms while receiving soy formula. Symptoms of 32 infants (53%) were unchanged or worse when they were fed cow's milk formula and soy formula, but symptoms disappeared when they were fed a formula containing hydrolyzed casein (Nutramigen). Symptoms of 17 infants (29%) could not be related to the diet; these infants were permitted to continue on a cow's milk-based formula. A challenge with cow's milk-based formula after one month (at approximately age 3 months) produced symptoms of infantile colic in 22 infants (36%). At age 6 months, a challenge with cow's milk was positive in 11 infants (18%) with epidermal and gastrointestinal symptoms. Eight infants (13%) at 12 months of age and five infants (8%) at 16 months of age were still intolerant to cow's milk. Cow's milk seems to be a major cause of infantile colic in formula-fed infants. A dietary treatment is suggested for moderate or severe forms of the colic. Cow's milk protein intolerance is common later in infancy in these infants.

Soy Formula Doesn't Help Colic

PEDIATRICS ◽  
1983 ◽  
Vol 71 (2) ◽  
pp. 299-300
Author(s):  
LASSE LOTHE ◽  
TOR LINDBERG ◽  
IRÉNE JAKOBSSON
Keyword(s):  
Adverse Reaction ◽  
Soy Protein ◽  
Milk Proteins ◽  
Cow’S Milk ◽  
Milk Formula ◽  
Cow's Milk ◽  
Cow’S Milk Proteins

In Reply.— We fully agree with LeBlanc that there was no significant improvement when infants with colic were given a soy protein-based formula. As pointed out in the "Discussion," as many as 53% of the infants showed an adverse reaction to soy (corresponding figure for cow's milk formula was 71%). We also emphasized that these figures must be interpreted with caution. In fact, soy protein-based formula was a bad choice as placebo. A placebo substance should be a substance of no importance as an allergen in infancy and soy protein has been shown to be as antigenic as cow's milk proteins (Eastham EJ, et al: J Pediatr 1978;93:561).

Manganese Absorption from Human Milk, Cow’s Milk and Infant Formulas

1988 ◽  
pp. 511-512 ◽  
Author(s):  
L. Davidsson ◽  
Å. Cederblad ◽  
B. Lönnerdal ◽  
B. Sandström
Keyword(s):  
Human Milk ◽  
Cow’S Milk ◽  
Infant Formulas ◽  
Cow's Milk

Levels of polychlorinated dibenzodioxins and dibenzofurans in cow's milk and in soy bean derived infant formulas sold in the United States and other countries

Chemosphere ◽  
1989 ◽  
Vol 19 (1-6) ◽  
pp. 913-918 ◽  
Author(s):  
Arnold Schecter ◽  
Peter Fürst ◽  
Christiane Fürst ◽  
Hans-Albert Meemken ◽  
Wilhelm Groebel ◽  
...  
Keyword(s):  
United States ◽  
The United States ◽  
Cow’S Milk ◽  
Infant Formulas ◽  
Cow's Milk ◽  
Polychlorinated Dibenzodioxins

Commentary on Breast-Feeding and Infant Formulas, Including Proposed Standards for Formulas

PEDIATRICS ◽  
1976 ◽  
Vol 57 (2) ◽  
pp. 278-285
Author(s):  
Lewis A. Barness ◽  
Alvin M. Mauer ◽  
Malcolm A. Holliday ◽  
Arnold S. Anderson ◽  
Peter R. Dallman ◽  
...  
Keyword(s):  
Human Milk ◽  
Breast Feeding ◽  
Growth And Development ◽  
Good Growth ◽  
Infant Formulas ◽  
Special Group ◽  
Term Infants ◽  
Excess Lead ◽  
Milk Substitute ◽  
Mineral Levels

This statement proposes recommendations toward increasing the practice of breast feeding. Specific recommendations made for standards of infant formulas as to calorie, protein, fat, vitamin, and mineral levels apply to both milk-based and milk-substitute infant formulas. Such formulas, when used in place of breast-feeding, must supply most or all of the nutrients infants require during the first weeks or months of life. The minimum levels of nutrients per 100 kcal recommended for formulas provide good growth and development in healthy, full-term infants; distinct hazards may be encountered at levels below these. However, no significant advantage is to be gained by providing levels in excess of these minima in normal infants. Recommendations for maximum levels are made only where quantities in excess lead to toxicity; generally, levels near the minima recommended are most desirable because they are the most likely to reflect the composition of human milk, and the least likely to result in any undesirable nutrient to nutrient interaction. The recommendations also can be used as reference standards for formulas for special dietary uses of "medical" formulas. The Committee recommends that "medical" formulas be classified by FDA into a special group under the paragraph dealing with infant formulas.

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