Adolescent Chest Pain

PEDIATRICS ◽  
1983 ◽  
Vol 72 (6) ◽  
pp. 916-916
Author(s):  
INGRID L. LANTNER

To the Editor.— I have some questions about Pantell and Goodman's article on adolescent chest pain. Was there any urine testing for cannabinoids? Were there inquiries regarding the use of marijuana? It's not unusual for teenagers to smoke this drug exclusively. In my pediatric practice, I have seen several adolescents with left-sided or substernal pain, in some instances not accompanied with chronic cough. The roentgenograms of the chest, EGG, tuberculosis tests, and other routine laboratory tests were negative, including some skin tests for respiratory allergies in a few.

1964 ◽  
Vol 11 (02) ◽  
pp. 506-512 ◽  
Author(s):  
V. A Lovric ◽  
J Margolis

SummaryAn adaptation of “kaolin clotting time” and prothrombin time for use on haemolysed capillary blood provided simple and sensitive screening tests suitable for use in infants and children. A survey of three year’s experience shows that these are reliable routine laboratory tests for detection of latent coagulation disorders.


2021 ◽  
Vol 8 (4) ◽  
pp. 1
Author(s):  
Jozélio Freire De Carvalho ◽  
Aaron Lerner

Objective: To describe a patient with presarcopenia and chronic cough secondary to chronic obstructive pulmonary disease (COPD) successfully treated with supplements and physical exercise.Case report: A 75-year-old female patient with a positive past medical history of systemic hypertension, dyslipidemia, heart arrhythmia, and smoking during 20 years evolved with chronic cough due to a chronic obstructive pulmonary disease diagnosed ten years ago. She came to our private clinic due to low weight, low energy. Her weight was 44.8 kg, her height 1.57 m, body mass index of 18.18 kg/m2. Laboratory tests showed SDHEA 76.3, vitamin D of 15.6 ng/ml (nr: > 30 ng/ml), C-reactive protein (CRP) of 55 mg/ml. Computed tomography showed bronchiectasis. She had an skeletal muscle mass index of 5.0 kg/m2 (nr: > 5.5 kg/m2) by DXA. A diagnosis of presarcopenia was determined based on DXA evaluation with low muscle mass but normal gait speed handgrip strength. We suggested to the patient to increase physical exercise and prescribed a supplement formula. After five months, she returned asymptomatic, without cough, marked improvement of fatigue, increased energy levels, and weight increased to 50 kg, BMI of 20.28 kg/m2. Laboratory tests showed SDHEA to 140, vitamin D3 to 64.5 ng/ml, reduced CRP reduced to 5 mg/dl, and amlodipine was excluded due to better blood pressure control. Currently, two years later, the patient continues without cough and has dyspnea only with high efforts, without fatigue, and her weight is 52 kg and BMI 21.1 kg/m2. She also reduced her conventional treatment for COPD, using only a bronchodilator on-demand, without topical corticoids.Conclusions: This case illustrates an interesting case of a patient with presarcopenia and chronic cough, refractory to conventional approach, successfully treated with a combination of nutraceuticals and physical exercises.


2020 ◽  
Vol 5 (5) ◽  
pp. 1038-1049 ◽  
Author(s):  
Anne Alnor ◽  
Maria B Sandberg ◽  
Charlotte Gils ◽  
Pernille J Vinholt

Abstract Background Severe acute respiratory syndrome coronavirus 2 causes coronavirus disease 2019 (COVID-19) and poses substantial challenges for healthcare systems. With a vastly expanding number of publications on COVID-19, clinicians need evidence synthesis to produce guidance for handling patients with COVID-19. In this systematic review and meta-analysis, we examine which routine laboratory tests are associated with severe COVID-19 disease. Content PubMed (Medline), Scopus, and Web of Science were searched until March 22, 2020, for studies on COVID-19. Eligible studies were original articles reporting on laboratory tests and outcome of patients with COVID-19. Data were synthesized, and we conducted random-effects meta-analysis, and determined mean difference (MD) and standard mean difference at the biomarker level for disease severity. Risk of bias and applicability concerns were evaluated using the Quality Assessment of Diagnostic Accuracy Studies-2. Summary 45 studies were included, of which 21 publications were used for the meta-analysis. Studies were heterogeneous but had low risk of bias and applicability concern in terms of patient selection and reference standard. Severe disease was associated with higher white blood cell count (MD, 1.28 ×109/L), neutrophil count (MD, 1.49 ×109/L), C-reactive protein (MD, 49.2 mg/L), lactate dehydrogenase (MD, 196 U/L), D-dimer (standardized MD, 0.58), and aspartate aminotransferase (MD, 8.5 U/L); all p < 0.001. Furthermore, low lymphocyte count (MD −0.32 × 109/L), platelet count (MD −22.4 × 109/L), and hemoglobin (MD, −4.1 g/L); all p < 0.001 were also associated with severe disease. In conclusion, several routine laboratory tests are associated with disease severity in COVID-19.


Case reports ◽  
2020 ◽  
Vol 6 (1) ◽  
pp. 63-69
Author(s):  
María Fernanda Ochoa-Ariza ◽  
Jorge Luis Trejos-Caballero ◽  
Cristian Mauricio Parra-Gelves ◽  
Marly Esperanza Camargo-Lozada ◽  
Marlon Adrián Laguado-Nieto

Introduction: Pneumomediastinum is defined as the presence of air in the mediastinal cavity. This is a rare disease caused by surgical procedures, trauma or spontaneous scape of air from the lungs; asthma is a frequently associated factor. It has extensive differential diagnoses due to its symptoms and clinical signs.Case presentation: A 17-year-old female patient presented with respiratory symptoms for 2 days, dyspnea, chest pain radiated to the neck and shoulders, right supraclavicular subcutaneous emphysema, wheezing in both lung fields, tachycardia and tachypnea. On admission, laboratory tests revealed leukocytosis and neutrophilia, and chest X-ray showed subcutaneous emphysema in the right supraclavicular region. Diagnosis of pneumomediastinum was confirmed through a CT scan of the chest. The patient was admitted for treatment with satisfactory evolution.Discussion: Pneumomediastinum occurs mainly in young patients with asthma, and is associated with its exacerbation. This condition can cause other complications such as pneumopericardium, as in this case. The course of the disease is usually benign and has a good prognosis.Conclusion: Because of its presentation, pneumomediastinum requires clinical suspicion to guide the diagnosis and treatment. In this context, imaging is fundamental.


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