Questions about Bilirubin

PEDIATRICS ◽  
1993 ◽  
Vol 91 (1) ◽  
pp. 164-165
Author(s):  
MARK SALERNO ◽  
MICHAEL ZACKIN ◽  
EVAN CHARNEY

To the Editor.— We are responding to the recent article entitled "Hyperbilirubinemia in Low Birth Weight Infants and Outcome at 5 Years of Age"1 as well as its predecessor "Hyperbilirubinemia in Preterm Infants and Neurodevelopmental Outcome at 2 Years of Age."2 Both articles are equally impressive for the quality of follow-up and the careful analysis of the data. However, there are several questions that merit clarification: 1. Three hundred sixty-one children from the original cohort died within the first 2 years of life, or 27% of the original cohort.

2016 ◽  
Vol 26 (5) ◽  
pp. 1349-1360 ◽  
Author(s):  
M. R. S. Moura ◽  
C. G. A. Araújo ◽  
M. M. Prado ◽  
H. B. M. S. Paro ◽  
R. M. C. Pinto ◽  
...  

1995 ◽  
Vol 104 (12) ◽  
pp. 963-968 ◽  
Author(s):  
Nancy M. Bauman ◽  
Bruce Benjamin

Acquired subglottic ductal cysts following prolonged intubation in preterm infants have been reported with increasing frequency during the past two decades. This paper reviews the subglottic ductal cysts diagnosed in 15 pediatric patients between 1989 and 1993 — the largest such review. Eighty percent were observed in preterm low-birth weight infants following prolonged intubation, and all but 3 of the patients had major intubation trauma of the larynx — an association not previously reported. The cysts were usually multiple and arose in the posterolateral subglottis. Most were small and did not cause significant airway obstruction, but associated intubation changes were sufficiently severe to necessitate tracheotomy in 10 patients. The cysts observed in our study did not enlarge and in 4 patients were observed to spontaneously resolve or shrink in size — trends not previously reported. Subglottic ductal cysts noted in preterm infants after prolonged intubation most commonly occur in association with laryngeal intubation trauma and are likely a component of intubation trauma. Although these cysts may resolve without therapy, careful follow-up and treatment of potentially obstructing subglottic ductal cysts is recommended.


2021 ◽  
Vol 11 (1) ◽  
Author(s):  
Stefania Longo ◽  
Camilla Caporali ◽  
Camilla Pisoni ◽  
Alessandro Borghesi ◽  
Gianfranco Perotti ◽  
...  

AbstractPreterm very low birth weight infants (VLBWi) are known to be at greater risk of adverse neurodevelopmental outcome. Identifying early factors associated with outcome is essential in order to refer patients for early intervention. Few studies have investigated neurodevelopmental outcome in Italian VLBWi. The aim of our longitudinal study is to describe neurodevelopmental outcome at 24 months of corrected age in an eleven-year cohort of 502 Italian preterm VLBWi and to identify associations with outcome. At 24 months, Griffiths’ Mental Developmental Scales were administered. Neurodevelopmental outcome was classified as: normal, minor sequelae (minor neurological signs, General Quotient between 76 and 87), major sequelae (cerebral palsy; General Quotient ≤ 75; severe sensory impairment). 75.3% showed a normal outcome, 13.9% minor sequelae and 10.8% major sequelae (3.8% cerebral palsy). Male gender, bronchopulmonary dysplasia, abnormal neonatal neurological assessment and severe brain ultrasound abnormalities were independently associated with poor outcome on multivariate ordered logistic regression. Rates of major sequelae are in line with international studies, as is the prevalence of developmental delay over cerebral palsy. Analysis of perinatal complications and the combination of close cUS monitoring and neurological assessment are still essential for early identification of infants with adverse outcome.


Author(s):  
Kousiki Patra ◽  
Michelle M. Greene ◽  
Grace Tobin ◽  
Gina Casini ◽  
Anita L. Esquerra-Zwiers ◽  
...  

1997 ◽  
Vol 97 (4) ◽  
pp. 386-390 ◽  
Author(s):  
STEPHANIE R. BRYSON ◽  
LEA THERIOT ◽  
NELL J. RYAN ◽  
JANET POPE ◽  
NANCY TOLMAN ◽  
...  

2002 ◽  
Vol 52 (3) ◽  
pp. 399-404 ◽  
Author(s):  
Rakesh Sahni ◽  
Deepak Saluja ◽  
Karl F Schulze ◽  
Sudha Kashyap ◽  
Kiyoko Ohira-Kist ◽  
...  

PEDIATRICS ◽  
1983 ◽  
Vol 71 (4) ◽  
pp. 541-546 ◽  
Author(s):  
Tzipora Dolfin ◽  
Martin B. Skidmore ◽  
Katherine W. Fong ◽  
Elizabeth M. Hoskins ◽  
Andrew T. Shennan

Real-time ultrasound scans were performed on 66 low-birth-weight infants within the first six hours of life (mean, two hours), and then at 12, 24, 48, and 72 hours, and thereafter at weekly intervals. All of the infants were born in a perinatal unit. The incidence of intraventricular hemorrhage and subependymal hemorrhage was 31%. Eight of 20 infants had small hemorrhages (Papile, grades I and II); seven infants sustained grade III hemorrhages, and five infants sustained grade Iv hemorrhages. All hemorrhages occurred in the first 72 hours of life; 25% were diagnosed with the first scan (ie, within the first six hours of life). The infants especially at risk were those less than 29 weeks's gestation. Five infants developed progressive posthemorrhagic ventriculomegaly that subsided spontaneously by age 8 weeks. The mortality in the study group was only 4.5%.


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