scholarly journals Diabetes mellitus, insulin therapy, oral antidiabetic, rational drug use

2020 ◽  
Vol 11 (3) ◽  
pp. 131-140
Author(s):  
Hacer Dinçoğlu

Diabetes mellitus (DM); is a metabolic progressive di-sease with a rapidly increasing prevalence. The most important factors in the treatment of DM is the education of individuals with diabetes and rational drug use. Multiple insulin therapy is started with the diagnosis in type 1 DM (T1DM), oral antidiabetic drugs (OAD) and insulin treatments are initiated together according to the glycemic status in Type 2 DM (T2DM). Problems causing irrational drug use related to OAD in DM; advanced age, multidrug use, complex drug intake program, lack of knowledge, drug-related side effects, and patient disbelief. Problems causing irrational drug use related to insulin; hypoglycemia, lipodystrophy, incorrect injection technique, insufficient and high dose administration. This situation appears as macrovascular and microvascular diseases with not reaching target HbA1c values by causing glycemic dysregulation in DM. The success of the holding of treatment in optimal status with prevention for glycemia and metabolic condition raises the quality of life in patients, prolong the patient’s life expectancy and reduces costs. Doctors and insulin educators raising awareness of rational drug use in the diabetic population ensures that correct the irrational behaviors performed in the diabetic population and adopt appropriate behaviors as a lifestyle. Thus it will improve the educational content given to people with diabetes, help to improve diabetes management and behavioral change, thereby achieving appropriate glycemic goals and increasing secondary rational gains from drugs with treatment.

2020 ◽  
Vol 6 (64) ◽  
pp. 2732-2739
Author(s):  
Fadime ÇINAR

2014 ◽  
Vol 5 (2) ◽  
Author(s):  
Moses A. Ojo ◽  
Cecilia I. Igwilo ◽  
Thomas Emedoh

Irrational drug use is associated with adverse consequences including drug resistance and avoidable adverse drug reactions. Studies of rational drug use in psychiatric facilities are scanty. This study evaluated prescription practices and perception of health care professionals regarding causes of irrational drug use. A retrospective study conducted at the outpatient clinic of Federal Neuro- psychiatric Hospital, Yaba, Lagos. Data on drug use indicators were analyzed. A cross-sectional assessment of perception of prescribers and dispensers regarding rational drug use was conducted. A total of 600 prescriptions were analyzed. Mean number of drugs per encounter was 3.5 and percentage generic prescribed was 58.5%. Poly-pharmacy (P=0.024, 95% CI=1.082-1.315) and non-generic prescribing (P=0.032, 95% CI=1.495-1.821) were significantly associated with young prescribers. Factors associated with irrational drug use include demand from patients, patients’ beliefs about injection drugs and influence of pharmaceutical sale representatives. Certain aspect of prescribers indicators are still poor in the hospital studied. Health care professionals identified possible associated factors for irrational drug use. Concerted efforts are required to ensure rational drug use especially in psychiatric facilities in Nigeria.


2021 ◽  
Author(s):  
Zhenhua Li ◽  
Qingcheng Yang ◽  
Xiangdong Zhang ◽  
Yanping Guo ◽  
Jiangang Zhang ◽  
...  

Objectives: To analyze the basic situations and clinical characteristics of stroke patients in our hospital from May 2018 to April 2021, lay a foundation for the prevention and reasonable treatment of stroke patients in northern Henan Province. Methods: The basic information of 835 stroke patients in our hospital was collected and classified according to age, gender, bad habits, accompanied diseases and drug use before admission to hospital, and severity of the stroke patients were also evaluated according to mRS scoring standard. Results: A total of 835 stroke patients were collected from May 2018 to April 2021 in our hospital. The age range of stroke patients was 28-95 years old, 96.29% stroke patients was above 40 years old; there were 202 stroke patients with smoking history and 225 stroke patients with drinking history; Among the 835 stroke patients, hypertension, cerebral infarction and diabetes mellitus were the main accompanied diseases. Antihypertensive drugs (506 cases), antiplatelet drugs (208 cases), statins (173 cases) and antidiabetic drugs (143 cases) were the main therapeutic drugs in stroke patients before admission in the northern Henan Province; the results of mRS scoring standard showed that among 835 stroke patients, there were 609 cases with milder symptoms, accounting for 82.84% (there were 330 stroke patients with 1 points, 279 stroke patients with 2 points, and 83 stroke patients with 3 points), and 120 cases with severe symptoms, accounting for 14.37% (55 cases with 4 points, 65 cases with 5 points). Conclusion: The age of stroke patients in northern Henan Province was mainly over 40 years old, most of stroke patients were in the early stage of stroke; smoking, drinking, hypertension and diabetes mellitus were main risk factors of stroke. And there was a sex difference between male stroke patients and female stroke patients in stroke risk factors smoking and hypertension. those data may help us for active prevention and rational drug use for stroke in clinic.


2020 ◽  
Vol 54 (4) ◽  
pp. 218-224
Author(s):  
Merve Nur Işık ◽  
Nazan Dalgıç ◽  
Betül Okuyan ◽  
Zeynep Yıldız Yıldırmak ◽  
Mesut Sancar

Objective: The aim of this study is to evaluate clinical pharmacist-led medication review service for hospitalized pediatric patients. Material and Methods: This cross-sectional study was carried out between November 2017-April 2018 in an education and research hospital in Istanbul. Clinical pharmacist-led medication review was conducted by using Pharmaceutical Care Network Europe (PCNE) Classification V8.02 in hospitalized pediatric at general pediatric service. Potential drug-related problems (DRPs) were identified and classified. These DRPs were presented the physicians and the percentage of accepted recommendations by the physician were recorded. Results: Among forty-three patients (21 male and 22 female), the median age of them was calculated as 6 (3-36) months. Of them, 25.58% had 16 DRPs. The most common DRPs were associated with potential drug-drug interactions (n= 9); and dose selection (n= 5), which represented 56.25% and 31.25% of drug-related problems, respectively. It was observed that 63% of these problems were occurred during selection of drugs (at prescription level) according to PCNE classification. Of the clinical pharmacist’s recommendations regarding these DRPs, 87.5% were accepted by the physician. Conclusion: To optimize rational drug use, numerous studies related with clinical pharmacist-led medication review by using PCNE classification were present in adult patients; however, there was no sufficient studies conducted in pediatric patients. Clinical pharmacists have an important role in the classification of DRPs and to provide rational drug use in pediatric patients.


2018 ◽  
Vol 2 (4) ◽  
Author(s):  
Jiangxia Yu ◽  
Yongtong Fan ◽  
Ruizhu Wu ◽  
Huanhuan Ji

Objective: To acquire information about residents of Changshou District's knowledge levels and their behaviors of drug use, so that implementation strategies of rational drug use can be formulated accordingly to promote and spread health education of rational drug use.  Methods:  Online and offline surveys were randomly conducted about rational drug use conditions of residents in Changshou District by questionnaires. Online questionnaires were sent to residents of Changshou District by Wenjuanxing, an professional platform used for surveys. Offline questionnaires were mainly distributed to residents of communities in Changshou District. All the online and offline statistics were analyzed and counted. Results: Three hundred and nine (309) questionnaires were distributed (176 online questionnaires and 133 paper questionnaires), and the effective recovery rate was 75.4%. According to investigation and survey, conditions of resident’s rational drug use were optimistic. Only 8.15% residents who participated in the survey (or research subjects) took paracetamol tablets and vitamin C Yinqiao tablets (also known as VC Honeysuckle Pills) at the same time when they had a cold or fever. Among 8.15% residents, 5.15% frequently took paracetamol, caffeine and aspirin powder (also known as headache powder); 80.26%, checked expiration date of drugs before taking medicine; more than 50%, knew that drinking after taking medicines such as cephalosporin is prohibited. Common irrational problems caused by drug use were as follows: 40% research subjects took dietary supplements as drugs, and 28% of them failed to know the correct usage and dosage of drugs. Proportion of drugs that were taken with irrational usage and dosage were antibiotics (64%), antibacterial (52%), drugs for patients with diabetes mellitus (36%), drugs for patients with hyperlipidemia , hypertension and hyperglycemia (32%), vitamins (24%), drugs for treatment of common cold and cough(20%) and others. Conclusion: Publicity of rational drug use should not be restricted to specific population, and knowledge of safe drug use is supposed to be actively popularized. Contents of rational drug use are as follows: Guide the public to correctly understand the functions of vitamins and dietary supplements strengthen publicity of rational use of drugs such as antibiotics, antibacterial drugs, drugs for chronic diseases, cold and cough, etc. Focus should be given on usage and dosage of drugs, use of antibacterial drugs, and repeated and excessive use of drugs caused by joint use of drugs with same ingredients of OTC drugs for treatment of common cold and cough.


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