scholarly journals The diagnostic value of ultrasound-guided percutaneous core needle biopsy of musculoskeletal soft tissue lesions

2021 ◽  
Vol 21 (84) ◽  
pp. e22-e33
Author(s):  
Paweł Szaro ◽  
◽  
Andrew Wong ◽  
Elena Blain ◽  
Khaldun Ghali Gataa ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Diagnostic Value ◽  
Ultrasound Guided ◽  
Core Needle ◽  
Soft Tissue Lesions ◽  
Percutaneous Core Needle Biopsy ◽  
Malignant Lesions ◽  
Solid Lesions

Introduction: Percutaneous ultrasound-guided core needle biopsy is a well-established method in the diagnosis of musculoskeletal tumors. It is unclear which factors contribute the most to a successful biopsy. The aim of the study was to determine the value of ultrasoundguided core needle biopsy of solid lesions in the musculoskeletal system using a 16-gauge needle. Material and methods: A retrospective analysis performed at a regional sarcoma center over one year included patients referred for ultrasound-guided biopsy of musculoskeletal soft tissue lesions. At least 6 months’ clinical and radiological follow-up, results from repeat or excisional biopsy, or interventional treatment, served as outcome reference. The biopsy procedure and yield were analyzed. The biopsy was classified as ‘diagnostic’ when a definitive diagnosis could be made on the first biopsy, and ‘accurate’ when only the malignant or benign nature of the tumor could be determined. Results: From 102 referrals for biopsy of soft tissue lesions in 2019, a total of 73 biopsies of solid lesions with a 16-gauge cutting needle were included (73 patients). There were 34 males and 39 females, with a mean age of 57.7 years. The overall proportion of diagnostic biopsies was 84%, for malignant lesions 88% and benign lesions 81%. The tumor could be classified as malignant or benign in 12 patients (16%) (accurate biopsy). It was possible to discriminate between malignant and benign lesions in each case. The majority of biopsied lesions were benign 64% (n = 47). Conclusion: The diagnostic value of ultrasound-guided percutaneous core needle biopsy of musculoskeletal soft tissue lesions performed with 16-gauge needle is good, with a high rate of diagnostic biopsies, both for benign and malignant lesions.

scholarly journals Diagnostic yield of percutaneous core needle biopsy in suspected soft tissue lesions of extremities

2019 ◽  
Vol 47 (6) ◽  
pp. 2598-2606 ◽  
Author(s):  
Dianwen Qi ◽  
Ming Zhao ◽  
Tongyu Hu ◽  
Guochuan Zhang
Keyword(s):  
Soft Tissue ◽  
Core Needle Biopsy ◽  
Predictive Value ◽  
Needle Biopsy ◽  
Diagnostic Yield ◽  
Benign Lesions ◽  
Core Needle ◽  
Soft Tissue Lesions ◽  
Percutaneous Core Needle Biopsy ◽  
Sensitivity Specificity

Objective This retrospective study was performed to investigate the diagnostic yield of percutaneous core needle biopsy (CNB) for suspected soft tissue lesions of the extremities. Methods The medical records of 139 consecutive patients who underwent percutaneous CNB for suspected soft tissue lesions of the extremities from January 2014 to December 2016 at a single institution were reviewed. The pathologic findings or clinical follow-ups were used to evaluate the performance of CNB. Alterations in the treatment regimen from pre- to post-biopsy were also analyzed. Complications, when present, were documented. Results In total, 141 biopsy procedures were performed in 139 patients. In total, 136 (96%) biopsies were successful, among which 5 were false-negative and 131 were diagnosed accurately. The sensitivity, specificity, accuracy, positive predictive value, and negative predictive value of CNB in the differentiation of malignant from benign lesions were 94%, 100%, 96%, 100%, and 90%, respectively. The treatment regimen was altered based on the biopsy findings in 25 cases. Two patients developed mild nerve injury but fully recovered during follow-up. Conclusions CNB is effective and safe, with high sensitivity, specificity, and accuracy for the diagnosis of soft tissue lesions, especially for differentiating malignant from benign lesions.

Image-guided percutaneous core needle biopsy of soft-tissue masses in the pediatric population

2016 ◽  
Vol 46 (8) ◽  
pp. 1173-1178 ◽  
Author(s):  
Terrence Metz ◽  
Amer Heider ◽  
Ranjith Vellody ◽  
Marcus D. Jarboe ◽  
Joseph J. Gemmete ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Pediatric Population ◽  
Core Needle ◽  
Image Guided ◽  
Percutaneous Core Needle Biopsy ◽  
Soft Tissue Masses

scholarly journals Accuracy and Safety of Ultrasound-Guided Core Needle Biopsy of Soft Tissue Tumors in an Outpatient Setting: A Sarcoma Center Analysis of 392 Consecutive Patients

Cancers ◽  
2021 ◽  
Vol 13 (22) ◽  
pp. 5659
Author(s):  
Helene Weigl ◽  
Peter Hohenberger ◽  
Alexander Marx ◽  
Nikolaos Vassos ◽  
Jens Jakob ◽  
...  
Keyword(s):  
Soft Tissue ◽  
Diagnostic Accuracy ◽  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Outpatient Service ◽  
Outpatient Setting ◽  
Safe Procedure ◽  
Ultrasound Guided ◽  
Core Needle ◽  
Tertiary Referral Center

Background: The aim of this study was to investigate diagnostic accuracy, safety and histologic results of ultrasound guided core needle biopsy (CNB) in patients with soft tissue lesions (STL) at a tertiary referral center. Methods: A retrospective analysis of all consecutive patients undergoing ultrasound guided CNB for STL at our sarcoma outpatient service between January 2015 and August 2020 was performed. Results: A total of 392 patients were identified. Main histologic entities were sarcomas, lipomas and desmoid tumors. Biopsy was performed in an outpatient setting in 87.6% of the cases. Conclusive biopsies were obtained in 88.5% of the cases. In patients who underwent surgical resection after CNB, the concordance of dignity, tumor entity and histopathological grading between biopsy and resection specimen were 97.2%, 92.7% and 92.5% respectively. The risk of inconclusive CNB was highest in intraabdominal or retroperitoneal tumors (19.5%) and lowest in lesions at the lower extremity (4.4%). Major complications after CNB occurred in three cases (0.8%). No case of biopsy tract seeding was observed during the study period. Conclusions: Ultrasound guided CNB for STL at first presentation in a dedicated surgical outpatient setting is a safe procedure and yields a high diagnostic accuracy.

scholarly journals Strategy for Diagnosing Breast Cancer in Indonesia during the COVID-19 Pandemic: Switching to Ultrasound-Guided Percutaneous Core Needle Biopsy

2021 ◽  
Vol 16 (3) ◽  
Author(s):  
Farida Briani Sobri ◽  
Adang Bachtiar ◽  
Sonar Soni Panigoro ◽  
Juwita Cresti Rahmaania ◽  
Patria Wardana Yuswar ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Patients ◽  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Hospital Environment ◽  
Breast Cancer Patients ◽  
Ultrasound Guided ◽  
Core Needle ◽  
The Us ◽  
Percutaneous Core Needle Biopsy

In this era of COVID-19, suspected breast cancer patients experience delay in diagnosis due to the fear of contracting the virus and reduction of non-COVID-19 health services. Furthermore, it may lead to potential increase in the incidence of advanced cancers in the future. Ultrasound-guided (US-guided) percutaneous core needle biopsy (CNB) is a great option for the diagnosis of cancer but it is poorly utilized. This study aimed to prove that the US-guided CNBis accurate when performed in a local setting and a potential solution for diagnosing breast cancer patients in this pandemic. In addition, it was a single health center cross-sectional study, and the participants were all breast cancer patients that had US-guided CNB from 2013-2019. The pathology results from US-guided CNB were compared to specimens from post-CNB surgeries. The data were collected from medical records and the immunohistochemistry (IHC) examinations were carried out for malignancy. There were 163 patients who were included in this study, 86 had malignancies and 77 had benign tumor reported in their CNB results. The US-guided CNB had 100% sensitivity and specificity compared to surgery. With its lower cost, time usage, and patient exposure to the hospital environment, US-guided CNB should replace open surgery biopsy for diagnosing suspicious breast cancers during the pandemic in Indonesia.

scholarly journals Diagnostic value and complication rate of ultrasound-guided transthoracic core needle biopsy in mediastinal lesions

PLoS ONE ◽  
2020 ◽  
Vol 15 (4) ◽  
pp. e0231523 ◽  
Author(s):  
Rosen Petkov ◽  
Tzvetan Minchev ◽  
Yordanka Yamakova ◽  
Evgeni Mekov ◽  
Georgi Yankov ◽  
...  
Keyword(s):  
Complication Rate ◽  
Core Needle Biopsy ◽  
Needle Biopsy ◽  
Diagnostic Value ◽  
Ultrasound Guided ◽  
Core Needle
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