Development and Validation of a Specific RP-HPLC Method for the Estimation of γ-Aminobutyric Acid in Rat Brain Tissue Samples Using Benzoyl Chloride Derivatization and PDA Detection

2015 ◽  
Vol 27 (3) ◽  
pp. 413-433 ◽  
Author(s):  
K. K. Akula ◽  
B. Chandrasekaran ◽  
M. Kaur ◽  
S. K. Kulkarni
Keyword(s):  
Rat Brain ◽  
Brain Tissue ◽  
Benzoyl Chloride ◽  
Hplc Method ◽  
Aminobutyric Acid ◽  
Tissue Samples ◽  
Rp Hplc ◽  
Development And Validation ◽  
Rat Brain Tissue

Argon Cluster Ion Source Evaluation on Lipid Standards and Rat Brain Tissue Samples

2013 ◽  
Vol 85 (16) ◽  
pp. 7745-7752 ◽  
Author(s):  
Claudia Bich ◽  
Rasmus Havelund ◽  
Rudolf Moellers ◽  
David Touboul ◽  
Felix Kollmer ◽  
...  
Keyword(s):  
Rat Brain ◽  
Brain Tissue ◽  
Ion Source ◽  
Tissue Samples ◽  
Source Evaluation ◽  
Cluster Ion Source ◽  
Cluster Ion ◽  
Rat Brain Tissue

scholarly journals A Simple Densitometric Method for the Quantification of Inhibitory Neurotransmitter Gamma-Aminobutyric Acid (GABA) in Rat Brain Tissue

2011 ◽  
Vol 2011 ◽  
pp. 1-5 ◽  
Author(s):  
Chidambaram Saravana Babu ◽  
Krishnamoorthy Selvarajan Kesavanarayanan ◽  
Periyathambi Kalaivani ◽  
Vijayan Ranju ◽  
Muthiah Ramanathan
Keyword(s):  
Rat Brain ◽  
Brain Tissue ◽  
High Performance ◽  
Aminobutyric Acid ◽  
Gamma Aminobutyric Acid ◽  
Inhibitory Neurotransmitter ◽  
Recovery Study ◽  
Layer Chromatography ◽  
Hptlc Method ◽  
Rat Brain Tissue

Gamma-aminobutyric acid (GABA) is the major inhibitory neurotransmitter in the mammalian central nervous system which is involved in various physiological and pathological processes. The present study demonstrates a simple high-performance thin-layer chromatography (HPTLC) method which was developed for the estimation of GABA in rat brain tissue. The method was validated in terms of precision, recovery, reproducibility, and variability. Instrumental precision was found to be 0.5891% CV and reproducibility of the method was found to be 0.4141% CV. Interday and intraday precision of the method was found to be 0.9453% and 1.3236% CV, respectively. Accuracy of the method was checked by the recovery study, and the average recovery of GABA was found to be 97.98% at 40 ng and 96.15% at 80 ng levels. The present HPTLC method for GABA estimation was found to be simple, precise, reproducible, sensitive, and accurate. No doubt, this proposed method will be a useful tool for the estimation of GABA in rat brain tissue.

Development and Validation of an LC/MS/MS Procedure for the Quantification of Endogenousmyo-Inositol Concentrations in Rat Brain Tissue Homogenates

2004 ◽  
Vol 76 (16) ◽  
pp. 4901-4908 ◽  
Author(s):  
Erick Kindt ◽  
Yin Shum ◽  
Lori Badura ◽  
Peter J. Snyder ◽  
Ashley Brant ◽  
...  
Keyword(s):  
Rat Brain ◽  
Brain Tissue ◽  
Tissue Homogenates ◽  
Development And Validation ◽  
Rat Brain Tissue

scholarly journals Discriminating healthy from tumor and necrosis tissue in rat brain tissue samples by Raman spectral imaging

2007 ◽  
Vol 1768 (10) ◽  
pp. 2605-2615 ◽  
Author(s):  
Nadia Amharref ◽  
Abdelilah Beljebbar ◽  
Sylvain Dukic ◽  
Lydie Venteo ◽  
Laurence Schneider ◽  
...  
Keyword(s):  
Rat Brain ◽  
Brain Tissue ◽  
Spectral Imaging ◽  
Tissue Samples ◽  
Raman Spectral ◽  
Rat Brain Tissue

scholarly journals Validation of a HPLC Method for Quantification of Thiamine and Its Phosphate Esters in Rat Brain Tissue

2017 ◽  
Vol 07 (02) ◽  
pp. 79-93
Author(s):  
Polliana Toledo Nunes ◽  
Patrícia da Silva Oliveira ◽  
Vany Ferraz ◽  
Angela Maria Ribeiro
Keyword(s):  
Rat Brain ◽  
Brain Tissue ◽  
Hplc Method ◽  
Phosphate Esters ◽  
Rat Brain Tissue
Sign in / Sign up

Export Citation Format

Share Document