Label Free DNA Detection Using Large Area Graphene-Based FET Biosensors

2011 ◽  
Vol 1359 ◽  
Author(s):  
Shirui Guo ◽  
Jian Lin ◽  
Miroslav Penchev ◽  
Emre Yangel ◽  
Mihrimah Ozkan ◽  
...  
Keyword(s):  
Mass Production ◽  
Field Effect Transistor ◽  
Dna Detection ◽  
Cost Effective ◽  
Label Free ◽  
Large Area ◽  
Covalent Functionalization ◽  
Free Dna ◽  
Highly Sensitive ◽  
Effect Transistor

ABSTRACTThis work describes the fabrication of highly sensitive graphene-based field effect transistor (FET) biosensors in a cost-effective way and its application in label-free DNA detection. CVD graphene was used to achieve mass production of FET device through photolithography method. Non-covalent functionalization of graphene with 1-Pyrenebutanoic acid succinimidyl ester ensures the high conductivity and sensitivity of the device. The present device could reach the low detection limit as low as 3*10-9 M.

Label Free DNA Detection Using Large Area Graphene Based Field Effect Transistor Biosensors

2011 ◽  
Vol 11 (6) ◽  
pp. 5258-5263 ◽  
Author(s):  
Shi-Rui Guo ◽  
Jian Lin ◽  
Miroslav Penchev ◽  
Emre Yengel ◽  
Maziar Ghazinejad ◽  
...  
Keyword(s):  
Field Effect ◽  
Field Effect Transistor ◽  
Dna Detection ◽  
Label Free ◽  
Large Area ◽  
Free Dna ◽  
Effect Transistor

Ultrasensitive in Situ Label-Free DNA Detection Using a GaN Nanowire-Based Extended-Gate Field-Effect-Transistor Sensor

2011 ◽  
Vol 83 (6) ◽  
pp. 1938-1943 ◽  
Author(s):  
Chin-Pei Chen ◽  
Abhijit Ganguly ◽  
Ching-Ying Lu ◽  
Ting-Yu Chen ◽  
Chun-Chiang Kuo ◽  
...  
Keyword(s):  
Field Effect ◽  
Field Effect Transistor ◽  
Dna Detection ◽  
Label Free ◽  
Free Dna ◽  
Gan Nanowire ◽  
Effect Transistor

scholarly journals Wafer-scale HfO2 encapsulated silicon nanowire field effect transistor for efficient label-free DNA hybridization detection in dry environment

2019 ◽  
Vol 30 (18) ◽  
pp. 184002 ◽  
Author(s):  
Ganesh Jayakumar ◽  
Maxime Legallais ◽  
Per-Erik Hellström ◽  
Mireille Mouis ◽  
Isabelle Pignot-Paintrand ◽  
...  
Keyword(s):  
Dna Hybridization ◽  
Field Effect ◽  
Field Effect Transistor ◽  
Silicon Nanowire ◽  
Label Free ◽  
Wafer Scale ◽  
Free Dna ◽  
Effect Transistor ◽  
Hybridization Detection

scholarly journals Printed, cost-effective and stable poly(3-hexylthiophene) electrolyte-gated field-effect transistors

2020 ◽  
Vol 8 (43) ◽  
pp. 15312-15321
Author(s):  
Davide Blasi ◽  
Fabrizio Viola ◽  
Francesco Modena ◽  
Axel Luukkonen ◽  
Eleonora Macchia ◽  
...  
Keyword(s):  
Field Effect ◽  
Field Effect Transistor ◽  
Field Effect Transistors ◽  
Cost Effective ◽  
Continuous Operation ◽  
Large Area ◽  
Ink Jet ◽  
Effect Transistor

A large-area processable ink-jet-printed poly(3-hexylthiophene) electrolyte-gated field-effect transistor, designed for bioelectronic applications, is proven to be stable for one week of continuous operation.

Hierarchical optical antenna: Gold nanoparticle-modified photonic crystal for highly-sensitive label-free DNA detection

2012 ◽  
Vol 22 (16) ◽  
pp. 8127 ◽  
Author(s):  
Weizhi Shen ◽  
Mingzhu Li ◽  
Benli Wang ◽  
Jian Liu ◽  
Zhiyuan Li ◽  
...  
Keyword(s):  
Photonic Crystal ◽  
Gold Nanoparticle ◽  
Dna Detection ◽  
Optical Antenna ◽  
Label Free ◽  
Free Dna ◽  
Highly Sensitive

Gold nanoparticles functionalized poly(3,4-ethylenedioxythiophene) thin film for highly sensitive label free DNA detection

2013 ◽  
Vol 5 (3) ◽  
pp. 684-689 ◽  
Author(s):  
S. Radhakrishnan ◽  
C. Sumathi ◽  
V. Dharuman ◽  
J. Wilson
Keyword(s):  
Thin Film ◽  
Gold Nanoparticles ◽  
Dna Detection ◽  
Label Free ◽  
Free Dna ◽  
Highly Sensitive

Fabrication of Si Nanowire Field-Effect Transistor for Highly Sensitive, Label-Free Biosensing

2009 ◽  
Vol 48 (6) ◽  
pp. 06FJ04 ◽  
Author(s):  
Takashi Kudo ◽  
Toshihiro Kasama ◽  
Takeshi Ikeda ◽  
Yumehiro Hata ◽  
Shiho Tokonami ◽  
...  
Keyword(s):  
Field Effect ◽  
Field Effect Transistor ◽  
Label Free ◽  
Si Nanowire ◽  
Highly Sensitive ◽  
Effect Transistor

scholarly journals Step-gate polysilicon nanowires field effect transistor compatible with CMOS technology for label-free DNA biosensor

2013 ◽  
Vol 40 (1) ◽  
pp. 141-146 ◽  
Author(s):  
G. Wenga ◽  
E. Jacques ◽  
A-C. Salaün ◽  
R. Rogel ◽  
L. Pichon ◽  
...  
Keyword(s):  
Field Effect ◽  
Field Effect Transistor ◽  
Cmos Technology ◽  
Dna Biosensor ◽  
Label Free ◽  
Free Dna ◽  
Effect Transistor

Real-time sensing of hepatitis B virus X gene using an ultrasensitive nanowire field effect transistor

2014 ◽  
Vol 34 (3) ◽  
pp. 273-277 ◽  
Author(s):  
Chia-Yu Wu ◽  
Han-Yi Cheng ◽  
Keng-Liang Ou ◽  
Chi-Chang Wu
Keyword(s):  
Hepatitis B Virus ◽  
Hepatitis B ◽  
Real Time ◽  
Field Effect ◽  
Field Effect Transistor ◽  
Label Free ◽  
Gene Detection ◽  
Highly Sensitive ◽  
B Virus ◽  
Effect Transistor

Abstract Devices based on semiconducting nanowires (NWs) are functioning as highly sensitive and selective sensors for the label-free detection of biological and chemical species. This paper demonstrates a novel back-gated silicon NW field effect transistor (NWFET) for gene detection. The fabricated NWFET was employed as the biomolecule sensor for the early, real-time, and label-free screening of hepatitis B virus (HBV) X gene. The DNA fragment in HBV demonstrates the linearity from 10 fM to 1 pM, of which the detection limit is estimated to be about 3.2 fM. The obtained results also show that the NW-based sensor can distinguish the difference between the complementary and 1-base mismatch DNA. The back-gated NW FET exhibits a label-free, highly sensitive, and selective biosensor for gene detection, which also provides a possibility of multiple chemical and biological species detection with sensor array in an integrated chip.

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