scholarly journals Association of Body Mass Index and Waist Circumference with Prostate-Specific Antigen

2021 ◽  
Vol 27 (2) ◽  
pp. 71-74
Author(s):  
Jin Lee ◽  
Hwang Sik Shin ◽  
Yong Jin Cho ◽  
Jeung Eun Oh

Objective: Prostate-specific antigen (PSA) is widely used as a screening tool of prostate cancer, although there has been a controversy about efficacy. In Korea, rapid growth of obesity prevalence in adult men is a one of the biggest health problems. The objective of this study was to evaluate the potential association between body mass index (BMI), waist circumference (WC) and PSA.Methods: We calculated BMI and WC of a total of 25,603 males who visited the Soonchunhyang University Cheonan Hospital Health Promotion Center from January 2016 to December 2020. This was categorized as follows: BMI < 23 kg/m2 (normal), 23 kg/m2 ≤ BMI < 25 kg/m2 (overweight), BMI ≥ 25 kg/m2 (obesity) and WC < 90 cm (normal), WC ≥ 90 cm (abdominal obesity). We analyzed the association between BMI, WC and PSA.Results: The mean PSA value was 1.08 ng/mL, 1.03 ng/mL, and 0.97 ng/mL at normal, overweight, and obesity group, respectively. The mean PSA value was 1.04 ng/mL and 0.96 ng/mL at normal and abdominal obesity group. Thus, the mean PSA value decreased with an increase in BMI and WC category (P < 0.001). The correlation coefficient between BMI, WC and PSA was -0.055, -0.044 and they were statistically significant (P < 0.001).Conclusion: We observed a significant negative correlation between BMI, WC and PSA value. Therefore, PSA value should be considered in relation to BMI and WC.

Author(s):  
Eyam Sunday Eyam ◽  
Ima-Abasi E. Bassey ◽  
Edoise M. Isiwele ◽  
Eyam Lilian Eberechukwu

Background: Prostate-specific antigen density (PSAD) is one of the means of improving PSA sensitivity as a marker of a prostate cancer diagnosis. However, this ability is perceived to be obscured by certain factors such as high body mass index and age in Caucasian and western populations, which tends to reduce its sensitivity and lead to misclassification of at-risk patients for prostate cancer. Aim: We studied the correlation of body mass index (BMI) and age with prostate-specific antigen density (PSAD) as indicators of prostate cancer risk in a screened male population(40 years and above) in the University of Calabar, Nigeria. Study Design: A cross-sectional analytical study with consecutive participant recruitment. Place and Duration of Study: The study was carried out in the University of Calabar Medical centre during a medical outreach. Materials and Methods: The study involved sixty-one (61) healthy male participants. BMI was mathematically determined from the weight and height and was categorized as underweight, normal weight, overweight and obesity based on the WHO classification with values of <18.5, 18.5-24.9, 25.0-29.9, and ≥30 (Kg/m2) respectively. Blood samples were collected and analyzed for PSA and transrectal ultrasound scan was done to estimate the prostate volume and was used to calculate the prostate-specific antigen density. Results: Over 67% of participants had PSA values below 4.0 ng/ml, 14.8% between 4.0-10.0 ng/ml, and 18% above 10.0 ng/ml. Body mass index (BMI) assessment revealed that 1.6% of the sampled population had BMI <18.5 Kg/m2, 32.8% had BMI between 18.5 Kg/m2 and 24.9 Kg/m2, while 50.8% were noticed to have a BMI of between 25.0 Kg/m2 and 29.9 Kg/m2, and 14.8% had BMI of 30 Kg/m2 and above. Conclusion: There was an inverse correlation of BMI with prostate-specific antigen density (PSAD) and a direct correlation of age with PSAD in this study of Nigerian men.


2021 ◽  
Vol 100 (4) ◽  
pp. 347-357
Author(s):  
Sofya N. Zimina ◽  
Marina A. Negasheva ◽  
Irina M. Sineva

Introduction. The aim of the study. The investigation of the time-related dynamics of adiposity parameters in a socially and economically homogenous group of young people. To determine the pattern of change in their health parameters and assess the prevalence of different diseases associated with increased body weight. Materials and methods. This study used the research titled "Massive anthropometric monitoring of physical development parameters of children, teenagers, and students" conducted from 2000 to 2018. The body mass index (BMI) of more than 6,400 students aged 17-18 years (2,971 young males and 3,418 young females) was examined. Then, we calculated the prevalence of underweight, overweight, and obesity among them. To determine the degrees of obesity, we compared the BMI values in our study with the World Health Organization's BMI ranges for corresponding age. Results. Over the study period, the mean BMI values and 5th and 15th BMI percentiles were characterized by weak positive time-related trends. Furthermore, 85th and 95th percentiles demonstrated a higher rate of increased data values (female students). From 2000 to 2018, the prevalence of overweight among female students increased from 5.2% to 10.5%, and that of obesity rose from 1.7% to 4.6%. For male students, no significant increase occurred in the overweight prevalence. Conclusions. To prevent chronic diseases associated with increased fat mass, attention should be paid to the mean values of different overweight parameters and the prevalence of extreme meanings in extensive population observations. Increased BMI among young females aged 17-18 years implies their possible elevated risk of cardiovascular diseases and other associated disorders later in life, related to nutrition disorders and lifestyle.


2005 ◽  
Vol 173 (4S) ◽  
pp. 401-401
Author(s):  
Javier Hernandez ◽  
Jacques Baillargeon ◽  
Brad Pollock ◽  
Alan R. Kristal ◽  
Patrick Bradshaw ◽  
...  

Author(s):  
Tapaswini Mishra ◽  
Dipti Mohapatra ◽  
Manasi Behera ◽  
Srimannarayan Mishra

ABSTRACTObjective: Adequate sleep has been considered important for the adolescent’s health and well-being. On the other hand, self-imposed sleepcurtailment is now recognized as a potentially important and novel risk factor for obesity. The objective of the study is to find the association betweenshort sleep duration and obesity (by calculating the body mass index [BMI]) among medical students.Methods: The study was conducted on 100 medical students. A brief history of sleep duration was taken. The height and weight were taken and thebody mass index (BMI) was calculated by formula weight in kg / height in m. Based on the BMI criteria the students were classified into six groups:Underweight, normal, overweight, obese class I, obese class II and obese III. The waist circumference (WC) was also taken. The data obtained werestatistically analysed by ANOVA test and the p < 0.5 was considered significant.2Results: The present cross-sectional study showed that there is an association between short sleep duration and obesity which was highly significant(p<0.001). This study also shows that there is an association between short sleep duration and waist circumference which was also highly significant(p<0.001).Conclusion: The present study observed a high association of short sleep duration among medical students of IMS and SUM Hospital and that shortsleep duration was significantly associated with increased risk of overweight and obesity. We should further investigate whether adults adopting ahealthy lifestyle with short sleep duration would improve their sleeping habits or not.Keywords: Sleep duration, Body mass index, Waist circumference, Obesity.


2017 ◽  
Vol 27 (1) ◽  
pp. 56 ◽  
Author(s):  
Willian R. Tebar ◽  
Luiz Carlos M. Vanderlei ◽  
Catarina C. Scarabotollo ◽  
Edner F. Zanuto ◽  
Bruna T. C. Saraiva ◽  
...  

Objectives: The aim of this study was to determine the prevalence of abdominal obesity and its associated factors among adolescents, independent of confounders. Method: A sample of 14–17-year-old individuals (n=1.231), who were students from Londrina/PR-Brazil public schools, was studied. A questionnaire about physical activity, sedentary behaviour and socioeconomic conditions was applied. Anthropometry was composed of body weight (kg), height (m), body mass index (BMI=kg/m²) and waist circumference (cm). The association of abdominal obesity and independent variables was assessed using the chi-square test and the magnitude of associations was verified using Binary Logistic Regression in an unadjusted model and adjusted for confounders (gender, age, socioeconomic status, physical activity and sedentary behaviour). The confidence interval and statistical significance were set at 95% and 5%, respectively, using SPSS v15.0. Results: The abdominal obesity prevalence was 17.5% (CI = 15.4%–19.6%), and was higher in boys than in girls. Adolescents with abdominal obesity had higher values of body weight, height, body mass index and sedentary behaviour compared to eutrophic individuals. Being male increased the risk of abdominal obesity by 36% in adolescents. This risk was two times higher in those with high levels of sedentary behaviour. Conclusion: Abdominal obesity was significantly associated with gender and high levels of sedentary behaviour, regardless of confounding factors. Lifestyle habits are important modifiable risk factors that can effectively contribute to the reduction of obesity from an early age.


2009 ◽  
Vol 182 (6) ◽  
pp. 2646-2652 ◽  
Author(s):  
Stacy Loeb ◽  
H. Ballentine Carter ◽  
Edward M. Schaeffer ◽  
Luigi Ferrucci ◽  
Anna Kettermann ◽  
...  

2019 ◽  
Vol 98 (7) ◽  
pp. E81-E86 ◽  
Author(s):  
Mehmet Surmeli ◽  
Ildem Deveci ◽  
Hasan Canakci ◽  
Mustafa Salih Canpolat ◽  
Burak Karabulut ◽  
...  

In this study, we aimed to investigate the relationship between the body mass index (BMI) and the morphometric properties of auricula and its acoustic gain characteristics. A total of 45 participants between 18 and 45 years of age were enrolled into the study. Participants’ height and weight measurements were recorded for the BMI calculation. On both sides, the morphometric properties of the auricula were measured and recorded. Additionally, the participants were subjected to multidirectional dynamic real ear measurements (REMs) to specify the intensity and frequency values of the maximum hearing gain. Participants consisted of 24 women and 21 men. The mean BMI was 23.42. The mean auricular area was 22.70 cm2. Statistically significant positive correlation was found between the auricular area and BMI ( r = 0.427, P = .03). The mean postauricular sulcus angle was 20.99°. The mastoid-helix distance was 16.07 mm. There was no statistically significant correlation between BMI level and postauricular sulcus angle and mastoid-helix distance ( P > .05). The mean dynamic REM measurement was evaluated. The maximum acoustic gain at anterior, lateral, and posterior vectorial stimulation was calculated as 20.9, 24.2, and 20.7 dB Sound Presure Level (SPL), respectively. Statistically significant negative correlation was found between the three directions acoustic gain level and BMI in the statistical examination ( r = −0.365, r = −0.386, r = −0.453, respectively, and P < .05 for all). The results of acoustic gain frequency were 2967.4, 2963, and 2934 Hz, respectively. There was no statistically significant correlation between acoustic gain frequency and BMI ( P > .05). When participants were grouped according to their BMI, participants with a BMI >25 had a statistically significantly bigger auricular area and lower maximum acoustic gain when compared with those with BMI <25 ( P < .05). We found that the auricular area increased with BMI. We think that this is related to soft tissue thickening of the auricula related to high BMI. In addition, we found that the acoustic gain level decreased inversely with BMI. We believe that the decrease in acoustic gain is due to the increase of acoustic resistance after the increase of soft tissue thickness. In conclusion, we think that BMI has a negative effect on auditory function according to findings in our study.


1993 ◽  
Vol 27 (4) ◽  
pp. 271-276 ◽  
Author(s):  
Maria I. Schmidt ◽  
Bruce B. Duncan ◽  
Mário Tavares ◽  
Carísi A. Polanczyk ◽  
Lúcia Pellanda ◽  
...  

In order to evaluate the validity of self-reported weight for use in obesity prevalence surveys, self-reported weight was compared to measured weight for 659 adults living in the Porto Alegre county, RS Brazil in 1986-87, both weights being obtained by a technician in the individual's home on the same visit. The mean difference between self-reported and measured weight was small (-0.06 +/- 3.16 kg; mean +/- standard deviation), and the correlation between reported and measured weight was high (r=0.97). Sixty-two percent of participants reported their weight with an error of < 2 kg, 87% with an error of < 4 kg, and 95% with an error of < 6 kg. Underweight individuals overestimated their weight, while obese individuals underestimated theirs (p<0.05). Men tended to overestimate their weight and women underestimate theirs, this difference between sexes being statistically significant (p=0.04). The overall prevalence of underweight (body mass index < 20) by reported weight was 11%, by measured weight 13%; the overall prevalence of obesity (body mass index > 30) by reported weight was 10%, by measured weight 11%. Thus, the validity of reported weight is acceptable for surveys of the prevalence of ponderosity in similar settings.


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