scholarly journals Sputum conversion among new smear positive pulmonary tuberculosis patients attending tb/dots clinics in Anambra state, Nigeria

2017 ◽  
Vol 2 (3) ◽  
Author(s):  
Nwachukwu Obiora Ndubuisi ◽  
Okoronkwo Christopher Uche ◽  
Onwuchekwa Chuks Elendu ◽  
Valentine Nnacheta Unegbu
Keyword(s):  
Pulmonary Tuberculosis ◽  
Tuberculosis Patients ◽  
Anambra State ◽  
Smear Positive Pulmonary Tuberculosis ◽  
Sputum Conversion

scholarly journals Factors Influencing Sputum Conversion among Smear-Positive Pulmonary Tuberculosis Patients in Morocco

2013 ◽  
Vol 2013 ◽  
pp. 1-5 ◽  
Author(s):  
Khalid Bouti ◽  
Mohammed Aharmim ◽  
Karima Marc ◽  
Mouna Soualhi ◽  
Rachida Zahraoui ◽  
...  
Keyword(s):  
Pulmonary Tuberculosis ◽  
Stepwise Regression ◽  
Control Measures ◽  
Sputum Smear ◽  
Tuberculosis Patients ◽  
Infection Control Measures ◽  
Factors Influencing ◽  
Smear Positive Pulmonary Tuberculosis ◽  
Sputum Conversion ◽  
A Prospective Study

Background. Sputum smear-positive pulmonary tuberculosis patients expel infectious viable bacilli for a period following the commencement of treatment. Objective. To determine the time to sputum smear conversion and study the factors influencing it. Design. A prospective study was undertaken at our hospital in Rabat over a six-month period on a cohort of 119 sputum smear positive patients. Patients were followed up fortnightly. At each followup, specimens were collected and processed for microscopy using standard protocol. Results. 96.6% of our patients completed the study (4 deaths). Sputum conversion rate was 42% after two weeks, 73% after one month, and 95% after two months. Univariate and stepwise regression analysis showed that patients who had high smear grading, miliary, and bilateral radiologic lesions were more likely to undergo delayed sputum conversion (P<0.05). Other factors were thought to influence sputum conversion but were not statistically proven in our study. Conclusion. Since viable bacilli continue to be expelled for up to two months, infection control measures should be maintained for such a time. Patients with high smear grading, miliary, and bilateral radiologic lesions need to be monitored more closely.

Socio-clinico-radiological profile of smear-positive pulmonary tuberculosis patients in association with sputum conversion and baseline hsCRP levels

2021 ◽  
pp. 004947552110421
Author(s):  
S Krishna Singha ◽  
Bineeta Kashyap ◽  
Rajnish Avasthi ◽  
Puneeta Hyanki ◽  
NP Singh ◽  
...  
Keyword(s):  
Pulmonary Tuberculosis ◽  
Inflammatory Marker ◽  
High Sensitivity ◽  
C Reactive Protein ◽  
Baseline Serum ◽  
Tuberculosis Patients ◽  
Protein Levels ◽  
Reactive Protein ◽  
Smear Positive Pulmonary Tuberculosis ◽  
Sputum Conversion

Our was an observational follow-up study where the aim was to assess the baseline high-sensitivity C-reactive protein levels in 50 smear-positive pulmonary tuberculosis patients in association with socio-clinico-radiological profile and microbiological conversion. Smear and culture conversion of sputum samples at the end of intensive phase of anti-tubercular treatment were recorded. Baseline serum high-sensitivity C-reactive protein estimation was done by ELISA. Mean high-sensitivity C-reactive protein levels at baseline, smear/culture converted and delayed converters were 68.1 ± 22.2 mg/l, 66.7 ± 22.0 mg/l and 91.6 ± 6.7 mg/l, respectively; high-sensitivity C-reactive protein levels were significantly higher in delayed converters as compared to sputum converters. Significantly higher baseline high-sensitivity C-reactive protein levels were seen in patients with bilateral chest X-ray lesions, cavitations, evening rise of temperature, haemoptysis and dyspnoea as compared to those without these features. high-sensitivity C-reactive protein, being a non-specific inflammatory marker could be an adjunct tool for TB prognosis.

scholarly journals Identification of intestinal abnormalities in patients with active pulmonary tuberculosis using small bowel capsule endoscopy

2018 ◽  
Vol 06 (09) ◽  
pp. E1103-E1108 ◽  
Author(s):  
Miwako Saitou ◽  
Daiki Nemoto ◽  
Kenichi Utano ◽  
Tomoko Suzuki ◽  
Alan Kawarai Lefor ◽  
...  
Keyword(s):  
Small Bowel ◽  
Pulmonary Tuberculosis ◽  
Capsule Endoscopy ◽  
Primary Outcome ◽  
Ileocecal Valve ◽  
Tuberculosis Patients ◽  
Active Pulmonary Tuberculosis ◽  
Intestinal Lesions ◽  
Smear Positive Pulmonary Tuberculosis ◽  
Small Intestinal

Abstract Background and study aims Mycobacterium tuberculosis is often detected in the feces of patients with active pulmonary tuberculosis. However, no study has examined the small intestine using small bowel capsule endoscopy (SBCE). This study aimed to investigate intestinal abnormalities in patients with active pulmonary tuberculosis. Patients and methods SBCE was performed in sputum/feces smear-positive pulmonary tuberculosis patients. From December 2013 to November 2016, 15 patients were enrolled from a dedicated tuberculous ward. The primary outcome was intestinal abnormalities identified by SBCE. Results Fourteen patients (median age 81 years, range 29 – 91; 3 female) underwent SBCE to the terminal ileum. The video was not recorded for one patient who was excluded from the analysis. Intestinal lesions, including 5 annular ulcers in 4 patients, were observed in 64 % (9/14). In subgroup analysis, prevalence tended to be higher in patients undergoing SBCE within 1 month of anti-tuberculous therapy (P = 0.051). Distribution of small intestinal lesions tended to be distal. Four of five annular ulcers were located close to the ileocecal valve. Conclusion Prevalence of intestinal lesions in patients with pulmonary tuberculosis is higher than expected before (UMIN 000017292)

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