scholarly journals The relationship of gene polymorphism with the heart failure risk in patients with hypertension and high adherence to treatment

2020 ◽  
Vol 25 (3) ◽  
pp. 3708
Author(s):  
N. A. Koziolova ◽  
A. I. Chernyavina
Keyword(s):  
Heart Failure ◽  
Gene Polymorphism ◽  
Adherence To Treatment ◽  
Failure Risk ◽  
High Adherence ◽  
Relationship Of ◽  
The Relationship

scholarly journals Diabetic cardiomyopathy: factual or factoid?

2019 ◽  
Vol 65 (1) ◽  
pp. 61-69
Author(s):  
Thiago Quinaglia ◽  
Daniela C. Oliveira ◽  
José Roberto Matos-Souza ◽  
Andrei C. Sposito
Keyword(s):  
Diabetes Mellitus ◽  
Heart Failure ◽  
Diabetic Cardiomyopathy ◽  
Glucose Transporter ◽  
Epidemiological Evidence ◽  
Glucose Lowering ◽  
Reduced Ejection Fraction ◽  
Prevention And Treatment ◽  
Relationship Of ◽  
The Relationship

SUMMARY Although long ago described, there is no established consensus regarding the real existence of Diabetic Cardiomyopathy (CMPDM). Due to its complex pathophysiology, it has been difficult for clinical and experimental research to establish clear connections between diabetes mellitus (DM) and heart failure (HF), as well as to solve the mechanisms of the underlying myocardial disease. However, the epidemiological evidence of the relationship of these conditions is undisputed. The interest in understanding this disease has intensified due to the recent results of clinical trials evaluating new glucose-lowering drugs, such as sodium-glucose transporter inhibitors 2, which demonstrated favorable responses considering the prevention and treatment of HF in patients with DM. In this review we cover aspects of the epidemiology of CMPDM and its possible pathogenic mechanisms, as well as, present the main cardiac phenotypes of CMPDM (HF with preserved and reduced ejection fraction) and implications of the therapeutic management of this disease.

scholarly journals The Adenosine Deaminase Gene Polymorphism Is Associated with Chronic Heart Failure Risk in Chinese

2014 ◽  
Vol 15 (9) ◽  
pp. 15259-15271 ◽  
Author(s):  
Hai-Rong He ◽  
Yuan-Jie Li ◽  
Gong-Hao He ◽  
Ya-Jun Wang ◽  
Ya-Jing Zhai ◽  
...  
Keyword(s):  
Heart Failure ◽  
Chronic Heart Failure ◽  
Gene Polymorphism ◽  
Adenosine Deaminase ◽  
Failure Risk
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