scholarly journals The influence that hepatic cirrhosis provides in exercise capacity and muscle strength: a review

2015 ◽  
Vol 28 (3) ◽  
pp. 617-625
Author(s):  
Renata Lopes Krüger ◽  
Bruno Costa Teixeira ◽  
Alexandre Simões Dias ◽  
Álvaro Reischak-Oliveira
Keyword(s):  
Muscle Strength ◽  
Exercise Capacity ◽  
Hepatic Cirrhosis ◽  
Retrieval System ◽  
Web Of Science ◽  
Scientific Literature ◽  
Negative Impact ◽  
Negative Effect ◽  
Neuromuscular Capacity

AbstractIntroduction Hepatic cirrhosis leads to a series of physiological changes, among which stand out cardiorespiratory and muscle impairments. These changes determine a negative impact on quality of life and may cause physical inactivity.Objective The objective of this study was to review, in the most current scientific literature, the influence that hepatic cirrhosis provides in exercise capacity and muscle strength, and the effect of exercise when applied to this situation.Materials and methods For this review, research on original studies was carried out on Medical Literature Analysis and Retrieval System Online (assessed by PubMed), Scopus and Web of Science between the years 1990 to 2015. In order to be included, studies had to meet the following criteria: a) be from original articles; b) evaluate exercise capacity or muscle strength; and c) provide relevant results.Results and Discussion : The majority of studies concluded that the exercise capacity and muscle strength are decreased in individuals with cirrhosis when compared to control subjects.Final considerations Hepatic cirrhosis has negative effect on cardiorespiratory and neuromuscular capacity during physical exercise in individuals with liver disease.

An interpretative phenomenological analysis of dignity in people with multiple sclerosis

2020 ◽  
Vol 27 (3) ◽  
pp. 686-700 ◽  
Author(s):  
Katarína Žiaková ◽  
Juraj Čáp ◽  
Michaela Miertová ◽  
Elena Gurková ◽  
Radka Kurucová
Keyword(s):  
Multiple Sclerosis ◽  
Lived Experience ◽  
Interpretative Phenomenological Analysis ◽  
Negative Impact ◽  
Phenomenological Analysis ◽  
Face To Face ◽  
Fighting Spirit ◽  
Negative Effect ◽  
Using Data

Background: Dignity is a fundamental concept in healthcare. The symptoms of multiple sclerosis have a negative effect on dignity. Understanding of lived experience of dignity in people with multiple sclerosis is crucial to support dignity in practice. Research aim: The aim was to explore the sense of dignity experienced by people with multiple sclerosis. Research design and participants: An interpretative phenomenological analysis design was adopted, using data collected through face-to-face interviews with 14 participants. Ethical considerations: The study was approved by the faculty Ethical Committee (No. EC 1828/2016). Findings: Four interconnected superordinate themes emerged from analysis: Loss of a fully-fledged life: Violating the dignity-of-self; To accept and fight: Promoting the dignity-of-self; Contempt and rudeness: Indignity-in-relation; and Those who know and see, help: Promoting dignity-in-relation. The loss of former fully-fledged life has a dramatic impact on integrity and impaired dignity-of-self. Accepting illness and changed identity impaired by multiple sclerosis was the step that the participants considered to be important for reacquiring the sense of dignity. The participants encountered misunderstandings, prejudices, embarrassment, insensitive remarks, labelling, unwillingness and impersonal treatment as indignities. Acceptance of their condition, needed support, the feeling of being part of a group, sensitivity and the sharing of problems had a positive effect on their dignity. Discussion: Continual changes in functional ability threaten an individual’s identity and were experienced as violations of dignity. Based on this, participant’s dignity-of-self was not a moral, but much more existential value. Acceptance of changed identity and fighting spirit were important for restoring their dignity-of-self. The misunderstandings, prejudices and unwillingness had a negative impact on their dignity-in-relation. On the other side, support from others in fighting promoted their dignity-in-relation. Conclusion: Dignity is manifested as a complex phenomenon of lived experience of people with multiple sclerosis and also an umbrella concept for providing good quality of person-centred care.

scholarly journals Effects of a Rehabilitation Programme with a Nasal Inspiratory Restriction Device on Exercise Capacity and Quality of Life in COPD

2020 ◽  
Vol 17 (10) ◽  
pp. 3669 ◽  
Author(s):  
Aurelio Arnedillo ◽  
Jose L. Gonzalez-Montesinos ◽  
Jorge R. Fernandez-Santos ◽  
Carmen Vaz-Pardal ◽  
Carolina España-Domínguez ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Muscle Strength ◽  
Exercise Capacity ◽  
Rehabilitation Program ◽  
Inspiratory Muscle ◽  
Control Group ◽  
6Mwt Distance ◽  
Before And After ◽  
Inspiratory Muscle Strength

Objective: The objective was to assess the effects of a nasal restriction device for inspiratory muscle training, called Feelbreathe®, added to a rehabilitation program (RP) on exercise capacity, quality of life, dyspnea and inspiratory muscle strength in patients with stable COPD. Methods: Patients were randomized into three groups, one performed a supervised RP using the Feelbreathe® device (FB group), the second group developed the same RP with oronasal breathing without FB (ONB group) and the third was the control group (CG). We evaluated inspiratory muscle strength (PImax), dyspnea (mMRC), quality of life (CAT) and exercise capacity (6MWT) before and after 8-week of RP. Results: A total of 16 patients completed the study, seven in FB group, five in ONB group and four in the CG. After the RP, the FB group showed a significant increase in PImax (93.3 ± 19.1 vs. 123.0 ± 15.8 mmHg) and in the 6MWT distance (462.9 ± 71.8 m vs. 529.1 ± 50.1 m) and a decrease in the CAT score (9.7 ± 6.5 vs. 5.9 ± 6.0) and in the mMRC dyspnea score. FB provides greater improvement in PImax, dyspnea, quality of life and 6MWT than ONB. Conclusions: The Feelbreathe® device provides greater improvements in quality of life, dyspnea, exercise capacity and inspiratory muscle strength compared to patients that did not use it.

scholarly journals The Role of Inspiratory Muscle Training in Sickle Cell Anemia Related Pulmonary Damage due to Recurrent Acute Chest Syndrome Attacks

2015 ◽  
Vol 2015 ◽  
pp. 1-6 ◽  
Author(s):  
Burcu Camcıoğlu ◽  
Meral Boşnak-Güçlü ◽  
Müşerrefe Nur Karadallı ◽  
Şahika Zeynep Akı ◽  
Gülsan Türköz-Sucak
Keyword(s):  
Quality Of Life ◽  
Muscle Strength ◽  
Exercise Capacity ◽  
Respiratory Muscle ◽  
Acute Chest Syndrome ◽  
Respiratory Muscle Strength ◽  
Muscle Training ◽  
Functional Exercise ◽  
Functional Exercise Capacity

Background. The sickling of red blood cells causes a constellation of musculoskeletal, cardiovascular, and pulmonary manifestations. A 32-year-old gentleman with sickle cell anemia (SCA) had been suffering from recurrent acute chest syndrome (ACS).Aim. To examine the effects of inspiratory muscle training (IMT) on pulmonary functions, respiratory and peripheral muscle strength, functional exercise capacity, and quality of life in this patient with SCA.Methods. Functional exercise capacity was evaluated using six-minute walk test, respiratory muscle strength using mouth pressure device, hand grip strength using hand-held dynamometer, pain using Visual Analogue Scale, fatigue using Fatigue Severity Scale, dyspnea using Modified Medical Research Council Scale, and health related quality of life using European Organization for Research and Treatment of Cancer QOL measurement.Results. A significant improvement has been demonstrated in respiratory muscle strength, functional exercise capacity, pain, fatigue, dyspnea, and quality of life. There was no admission to emergency department due to acute chest syndrome in the following 12 months after commencing regular erythrocytapheresis.Conclusion. This is the first report demonstrating the beneficial effects of inspiratory muscle training on functional exercise capacity, respiratory muscle strength, pain, fatigue, dyspnea, and quality of life in a patient with recurrent ACS.

scholarly journals A Warning Call for Fertility Preservation Methods for Women Undergoing Gonadotoxic Cancer Treatment

Medicina ◽  
2021 ◽  
Vol 57 (12) ◽  
pp. 1340
Author(s):  
Claudia Mehedintu ◽  
Francesca Frincu ◽  
Andreea Carp-Veliscu ◽  
Ramona Barac ◽  
Dumitru-Cristinel Badiu ◽  
...  
Keyword(s):  
Cancer Treatment ◽  
Fertility Preservation ◽  
Ovarian Reserve ◽  
Negative Impact ◽  
Future Fertility ◽  
Negative Effect ◽  
The One

Malignant hematological conditions have recognized an increased incidence and require aggressive treatments. Targeted chemotherapy, accompanied or not by radiotherapy, raises the chance of defeating the disease, yet cancer protocols often associate long-term gonadal consequences, for instance, diminished or damaged ovarian reserve. The negative effect is directly proportional to the types, doses, time of administration of chemotherapy, and irradiation. Additionally, follicle damage depends on characteristics of the disease and patient, such as age, concomitant diseases, previous gynecological conditions, and ovarian reserve. Patients should be adequately informed when proceeding to gonadotoxic therapies; hence, fertility preservation should be eventually regarded as a first-intention procedure. This procedure is most beneficial when performed before the onset of cancer treatment, with the recommendation for embryos or oocytes’ cryopreservation. If not feasible or acceptable, several options can be available during or after the cancer treatment. Although not approved by medical practice, promising results after in vitro studies increase the chances of future patients to protect their fertility. This review aims to emphasize the mechanism of action and impact of chemotherapy, especially the one proven to be gonadotoxic, upon ovarian reserve and future fertility. Reduced fertility or infertility, as long-term consequences of chemotherapy and, particularly, following bone marrow transplantation, is often associated with a negative impact of recovery, social and personal life, as well as highly decreased quality of life.

scholarly journals Pulmonary rehabilitation in lymphangioleiomyomatosis: a controlled clinical trial

2016 ◽  
Vol 47 (5) ◽  
pp. 1452-1460 ◽  
Author(s):  
Mariana S. Araujo ◽  
Bruno G. Baldi ◽  
Carolina S.G. Freitas ◽  
André L.P. Albuquerque ◽  
Cibele C.B. Marques da Silva ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Physical Activity ◽  
Muscle Strength ◽  
Exercise Capacity ◽  
Pulmonary Rehabilitation ◽  
Daily Physical Activity ◽  
Interquartile Range ◽  
Controlled Clinical Trial ◽  
Endurance Time

Lymphangioleiomyomatosis (LAM) is a cystic lung disease frequently associated with reduced exercise capacity. The aim of this study was to assess safety and efficacy of pulmonary rehabilitation in LAM.This controlled clinical trial included 40 patients with LAM and a low physical activity level. The pulmonary rehabilitation programme comprised 24 aerobic and muscle strength training sessions and education. The primary outcome was exercise capacity (endurance time during a constant work rate exercise test). Secondary outcomes included health-related quality of life (St George's Respiratory Questionnaire (SGRQ)), 6-min walking distance (6MWD), dyspnoea, peak oxygen consumption (V′O2), daily physical activity (pedometer), symptoms of anxiety and depression, lung function and peripheral muscle strength (one-repetition maximum).The baseline characteristics were well balanced between the groups. The pulmonary rehabilitation group exhibited improvements in the following outcomes versus controls: endurance time (median (interquartile range) 169 (2–303) s versus −33 (−129–39) s; p=0.001), SGRQ (median (interquartile range) −8 (−16–2) versus 2 (−4–5); p=0.002) and 6MWD (median (interquartile range) 59 (13–81) m versus 20 (−12–30) m; p=0.002). Dyspnoea, peak V′O2, daily physical activity and muscle strength also improved significantly. No serious adverse events were observed.Pulmonary rehabilitation is a safe intervention and improves exercise capacity, dyspnoea, daily physical activity, quality of life and muscle strength in LAM.

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