scholarly journals Omega 3 Fatty Acids Reduce the Triglyceride Levels in Rats with Apical Periodontitis

2018 ◽  
Vol 29 (2) ◽  
pp. 173-178 ◽  
Author(s):  
Mariane Maffei Azuma ◽  
João Eduardo Gomes-Filho ◽  
Carolina de Barros Morais Cardoso ◽  
Camila Barbosa Pipa ◽  
Luis Gustavo Narciso ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Bone Resorption ◽  
Apical Periodontitis ◽  
Male Rats ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Cholesterol Levels ◽  
Oral Environment ◽  
Pulp Exposure ◽  
The Difference

Abstract The aim of this study was to evaluate the influence of the prophylactic and therapeutic supplementation with omega 3 polyunsaturated fatty acids (w-3 PUFAs) on the lipid profile and periapical bone resorption in rats with apical periodontitis. Forty male rats were divided into groups: control rats (C), rats treated with w-3 PUFAs (C+O), rats with pulp exposure-induced apical periodontitis (AP), and rats with AP treated with w-3 PUFAs (AP+O). The administration of w-3 PUFAs was carried out orally once a day for 15 days before pulp exposure and, subsequently, for an additional 30 days after pulp exposure. AP was induced by exposing pulpal tissues to the oral environment. The samples were collected after 30 days. Triglycerides and cholesterol levels were enzymatically measured using the Trinder method. The jaws were collected and submitted for histological analysis. Two-way analysis of variance and Kruskal-Wallis tests were used for statistical analysis, and the significance was set at p<0.05. The triglyceride levels of the AP group were significantly higher than those of the C, C+O and AP+O groups (p<0.05). However, the difference in the cholesterol levels among the groups was not significant (p>0.05). Rats with AP showed larger areas of bone resorption as well as higher inflammatory intensity compared with rats with AP supplemented with w-3 PUFAs. It may be concluded that the presence of multiple AP foci increased the triglyceride levels. In addition, omega 3 supplementation might reduce these levels in rats with AP, as well as the bone resorption areas of periapical tissues.

scholarly journals Omega 3 Fatty Acids Reduce Bone Resorption While Promoting Bone Generation in Rat Apical Periodontitis

2017 ◽  
Vol 43 (6) ◽  
pp. 970-976 ◽  
Author(s):  
Mariane Maffei Azuma ◽  
João Eduardo Gomes-Filho ◽  
Edilson Ervolino ◽  
Camila Barbosa Pipa ◽  
Carolina de Barros Morais Cardoso ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Bone Resorption ◽  
Apical Periodontitis ◽  
Omega 3 Fatty Acids ◽  
Omega 3

scholarly journals Omega-3 Fatty Acid Oil Enhancement of a Protein-Based Recovery Beverage: Sensory Analysis with Athletes

2017 ◽  
Vol 6 (4) ◽  
pp. 83
Author(s):  
Jessica Marie MacMartin ◽  
W. E. Buckley ◽  
David Cranage ◽  
Tim Bream ◽  
Peter Lawrence Bordi
Keyword(s):  
Fatty Acids ◽  
Sensory Analysis ◽  
Female Athlete ◽  
Daily Intake ◽  
The United States ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Omega 3 Fatty Acid ◽  
United States Population ◽  
The Difference

Essential omega-3 fatty acids must be consumed through the diet to meet the body’s nutrition requirement. Daily-recommended intake of omega-3 fatty acids for adults is 270 milligrams/day. These fatty acids are commonly consumed through fish, but it is known that the United States population at large is not meeting their recommended daily intake. Supplements containing these important acids should be considered to close the gap between recommendations and actual intake. To create a product with these beneficial acids, sensory analysis was conducted to see if non-trained male and female athlete panelists could notice the difference in several key sensory characteristics (appearance, initial taste, color, sweetness, consistency, chocolate flavor, aftertaste, overall quality and overall liking) in a chocolate protein-based recovery beverage. The sensory-neutral oil was added into the beverage and athletes (n=95) were asked to taste the omega-3 and original beverage and rank each characteristic on hedonic and just-about-right scales. Color of the drink, aftertaste, overall quality and overall liking were rated significantly higher for the omega-3 added drink. Overall, the addition of the omega-3 fatty acids improved the beverage in several key attributes and can be added into the final formulation of the product. 

scholarly journals Inhibitory effect of omega-3 fatty acids on alveolar bone resorption and osteoclast differentiation

2020 ◽  
Vol 62 (3) ◽  
pp. 298-302 ◽  
Author(s):  
Yu Ozaki ◽  
Toshiya Morozumi ◽  
Kiyoko Watanabe ◽  
Toshizo Toyama ◽  
Haruka Sasaki ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Bone Resorption ◽  
Alveolar Bone ◽  
Osteoclast Differentiation ◽  
Inhibitory Effect ◽  
Omega 3 Fatty Acids ◽  
Omega 3

scholarly journals Impact of omega-3 fatty acids and/or plant sterol supplementation on non-HDL cholesterol levels of dyslipidemic Indian adults

2013 ◽  
Vol 5 (1) ◽  
pp. 36-43 ◽  
Author(s):  
Shweta Khandelwal ◽  
Rahul Shidhaye ◽  
Isabelle Demonty ◽  
Ramakrishnan Lakshmy ◽  
Ruby Gupta ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Plant Sterol ◽  
Hdl Cholesterol ◽  
Omega 3 Fatty Acids ◽  
Omega 3 ◽  
Cholesterol Levels

Omega-3 Fatty Acids Alter Systemic Inflammatory Mediators Caused by Apical Periodontitis

2020 ◽  
Author(s):  
Mariane Maffei Azuma ◽  
Carolina de Barros Morais Cardoso ◽  
Renata Oliveira Samuel ◽  
Camila Barbosa Pipa ◽  
Suely Regina Mogami Bomfim ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Inflammatory Mediators ◽  
Apical Periodontitis ◽  
Omega 3 Fatty Acids ◽  
Omega 3

scholarly journals Omega-3 Fatty Acids Reduce Inflammation in Rat Apical Periodontitis

2018 ◽  
Vol 44 (4) ◽  
pp. 604-608 ◽  
Author(s):  
Mariane Maffei Azuma ◽  
João Eduardo Gomes-Filho ◽  
Edilson Ervolino ◽  
Carolina de Barros Moraes Cardoso ◽  
Camila Barbosa Pipa ◽  
...  
Keyword(s):  
Fatty Acids ◽  
Apical Periodontitis ◽  
Omega 3 Fatty Acids ◽  
Omega 3

scholarly journals Fertility Enhancing Potency of Omega-3 Fatty Acids in Male Rats

2019 ◽  
Vol 62 ◽  
Author(s):  
Emmanuel Ikechukwu Nnamonu ◽  
Bernard Obialor Mgbenka ◽  
Edmund Chidiebere Mbegbu
Keyword(s):  
Fatty Acids ◽  
Male Rats ◽  
Omega 3 Fatty Acids ◽  
Omega 3

scholarly journals A Randomized, Prospective Study to Compare the Efficacy and Safety of Omega-3 Fatty Acids as Additional Therapy to Methotrexate versus Methotrexate Monotherapy in the Management of Moderate to Severe Plaque Psoriasis

2021 ◽  
Vol 6 (1) ◽  
pp. 1
Author(s):  
Ankita Bedwal ◽  
Kavitha Rajarathna ◽  
Revathi T.N.
Keyword(s):  
Fatty Acids ◽  
Adverse Events ◽  
Plaque Psoriasis ◽  
Epigastric Pain ◽  
Omega 3 Fatty Acids ◽  
Efficacy And Safety ◽  
Omega 3 ◽  
Severe Plaque Psoriasis ◽  
Number Of Patients ◽  
The Difference

Psoriasis is a chronic, inflammatory, hyperproliferative, immune-mediated skin disorder, having a prevalence of 0.44-2.8% in India. Methotrexate is a widely used systemic regimen for moderate to severe psoriasis. Supplementation of omega-3 fatty acids has decreased the severity of the disease in some studies. This study aimed to assess the efficacy and safety of omega-3 fatty acids as an add-on to methotrexate versus methotrexate monotherapy in patients with moderate to severe plaque psoriasis. A total of 40 patients with moderate to severe plaque psoriasis were recruited in the study and randomized into two groups of 20 patients each. Group O received omega-3 fatty acids as add-on to methotrexate and Group M received methotrexate monotherapy. Psoriasis Area and Severity Index (PASI), Dermatology Life Quality Index (DLQI), Physician’s Global Assessment (PGA) were assessed at baseline, 4 weeks, 8 weeks and 12 weeks of treatment. The adverse events were assessed throughout the study period. There was a significant decrease in PASI and DLQI scores from baseline to end of 12 weeks in both groups (p<0.001) but the difference between the two groups was not significant (p>0.05). A higher number of patients had a PGA score of 0 or 1 at the end of 12 weeks in Group O (60%) as compared to Group M (40%) but the difference between the groups was not significant (p=0.34). The treatment was well tolerated in both the groups, with most common adverse events being nausea, diarrhea and epigastric pain. This study showed that the treatment in both the groups was equally effective in decreasing the severity of psoriasis and was well tolerated.

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