scholarly journals Asymptomatic vertebral fractures in patients with low bone mineral density

2016 ◽  
Vol 62 (2) ◽  
pp. 145-150 ◽  
Author(s):  
Caio Cesar Leite de Negreiros ◽  
Marina Guareschi Berigo ◽  
Robson Luiz Dominoni ◽  
Deisi Maria Vargas

Summary Objective: Vertebral fracture assessment (VFA) is a test technique that can be used to detect asymptomatic vertebral fractures (AVF). It uses dual energy X-ray bsorptiometry (DXA) and can be performed concurrently with bone densitometry. This study aims to assess the prevalence of AVF in patients with low bone mass. Methods: Cross-sectional study including 135 individuals with low bone mineral density (BMD) with a T-score < -2.0 standard deviation (SD) in a densitometry clinic located in the city of Blumenau (state of Santa Catarina). Anthropometric, clinical and lifestyle variables were obtained from history-taking and physical examination. Densitometric variables were obtained by bone mineral densitometry and VFA (Explorer, Hollogic®). Vertebral fractures were classified according to the Genant criteria. Student's t, chi-square and logistic regression were performed for statistical analysis. Results: AVFs occurred in 24.4% of the subjects. They were older compared to those without AVF (65±9.25 versus 60.1±8.66; p=0.005), and had a history of lowimpact fractures (38.24% versus 19.8%; OR 2.5; p=0.03). Half of the patients that reported steroid therapy had AVFs, compared to one fifth of those who did not use steroids (50% versus 21.49%; OR 3.6; p=0.01). Conclusion: Asymptomatic vertebral fractures were present in approximately one fourth of patients. The risk factors associated were history of low-impact fracture, use of steroids and age > 61 years.

2009 ◽  
Vol 200 (11) ◽  
pp. 1746-1754 ◽  
Author(s):  
Alexandra Calmy ◽  
Christoph A. Fux ◽  
Richard Norris ◽  
Nathalie Vallier ◽  
Cécile Delhumeau ◽  
...  

2013 ◽  
Vol 13 (1) ◽  
Author(s):  
Ángel Matute-Llorente ◽  
Alejandro González-Agüero ◽  
Alba Gómez-Cabello ◽  
Germán Vicente-Rodríguez ◽  
José Antonio Casajús

Author(s):  
Ihsanullah Rajar ◽  
Nasrullah Aamer ◽  
Narindar Kumar ◽  
Prem Kumar ◽  
Kapeel Raja ◽  
...  

Objective: The objective of this study was to evaluate the low bone mineral density (BMD) in patients with liver cirrhosis. Methodology: This cross sectional study on 151 Liver cirrhotic patients was conducted at Liaquat University Hospital Hyderabad/Jamshoro. This study duration was 6 months, July 2015 to December 2015. The Assessment of bone mineral density (BMD) for each relevant patient was done using ultrasound impedance Dual Energy X-ray Absorptiometry  (DEXA) by senior pathologist having ≥05 years of experience, across the calcaneum, at lumbar spine  (LS) and femur neck (FN),  were computed by using computer supported device. The BMD was expressed in terms of T score. The WHO standard value was utilized to define the low BMD / osteoporosis is T score -1.5. Results: The mean age of subjects was 31.32±6.18 years. Out of all, 62.9% were males whereas 37.1% were females. About 21% patients had low/abnormal bone mineral density (BMD). Among these, 17.9% had bone mineral density (BMD) of -1.5 to -2.5 and 4% had BMD of <-2.5. Rest of 78.1% patients had a normal (>-1.5) bone mineral density (BMD). Majority of patients, 63.6% had a CTP grade B of liver cirrhosis, whereas 22.5% had A grade and 13.9% had C grade of liver cirrhosis. Conclusion: Conclusively, the risk of low bone mineral density (BMD) was evidently high for patients with hepatic cirrhosis. Male gender and age above 30 years were found at greater risk and CTP grade B of cirrhosis was most common.


2003 ◽  
Vol 11 (4) ◽  
pp. 470-486 ◽  
Author(s):  
Joyce E. Ballard ◽  
Lorraine S. Wallace ◽  
David B. Holiday ◽  
Cassandra Herron ◽  
Liberty L. Harrington ◽  
...  

This study assessed differences in bone-mineral density (BMD) and lean and fat tissues between 5 age groups of White men age 65–93 years. Lean and fat tissues were measured with absorptiometry and anthropometry, and BMD, with dual-energy X-ray absorptiometry. Forearm, spinal, and femoral T scores were used to classify BMD as normal, osteopenic, or osteoporotic. A questionnaire evaluated previous physical activity, calcium intake, and bone fractures. Significantly lower values in body weight, lean tissue, and forearm BMD occurred in the older age groups. Significant, positive relationships were found between total lean tissue and radial, spinal, and hip BMDs. For the total group, osteopenic and osteoporotic T scores, respectively, were femoral neck 70.6% and 9.8%, radius 27.5% and 25.5%, and spine 25.5% and 7.8%. Differences in BMD values were found between levels of lifestyle factors (dietary calcium and history of previous fractures). In conclusion, elderly men should be encouraged to maintain adequate total lean tissue because of its association with BMD.


2018 ◽  
Vol Volume 14 ◽  
pp. 663-669
Author(s):  
Tadasu Horai ◽  
Akitoyo Hishimoto ◽  
Ikuo Otsuka ◽  
Tatsuhiro So ◽  
Kentaro Mouri ◽  
...  

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