scholarly journals Altered intrauterine ultrasound, fetal head circumference growth and neonatal outcomes among suspected cases of congenital Zika syndrome in Brazil

2016 ◽  
Vol 16 (suppl 1) ◽  
pp. S7-S15 ◽  
Author(s):  
Alex Sandro Rolland Souza ◽  
Ariani Impieri de Souza ◽  
Silvia de Lourdes Loreto Faquin ◽  
Orlando Gomes dos Santos Neto ◽  
Emanuele Honorato ◽  
...  

Abstract Objectives: to describe altered intrauterine ultrasound, analyze fetal head circumference (HC) growth and neonates' outcomes among presumed cases of congenital Zika syndrome in Brazil. Methods: 30 women were included in the study with suspected history of Zika virus (ZIKV) infection during pregnancy and fetal's brain altered on ultrasound diagnosis. Sociodemographic and obstetric characteristics, prenatal altered ultrasounds, HC and other perinatal outcomes have been described. The relation between HC and gestational age was analyzed by using random regression effects based on polynomials fractions. The Z test was calculated to determine an instant variant mean rate of the HC for each gestational age. Results: the mean gestational age of the ultrasound diagnosis was 33.3 + 4.7 weeks and HC at birth was 28.9 + 1.6 cm. The main altered brain ultrasound was microcephaly (96.7%). The analysis of the fetal head circumference showed an estimated increase of the average HC, as to gestational age, it did not occur in a linear form. The instant HC variation rate increased according to gestational age (p<0,001). Conclusions: Fetal's main morphological alteration was microcephaly, observing an increase in the head circumference according to gestational age in a non-linear form and the variation decreased with gestational age.

2020 ◽  
Vol 78 (7) ◽  
pp. 403-411
Author(s):  
Thais MASSETTI ◽  
Dafne HERRERO ◽  
Julliana ALENCAR ◽  
Talita SILVA ◽  
Cristina MORIYAMA ◽  
...  

ABSTRACT Background: The congenital Zika syndrome involves structural brain changes, including ventriculomegaly, thin cerebral cortices, abnormal gyral pattern, cortical malformations, hypoplasia of the corpus callosum, myelination delay, subcortical diffuse calcifications, brainstem hypoplasia, and microcephaly in newborns. Objective: This study aimed to describe the clinical characteristics of children with congenital Zika syndrome; to compare the outcomes of infants infected in the first (1T, n=20) and second trimesters of pregnancy (2T, n=11); to investigate correlations between birth weight, birth and follow-up head circumference, birth gestational age, and gross motor scores. Methods: Participants were evaluated with Alberta Infant Motor Scale (AIMS) and part A of the Gross Motor Function Measure (GMFM-A). ANOVA compared head circumference, birth gestational age, birth weight, and gross motor performance of 1T and 2T. Results: The correlations were investigated by Pearson correlation coefficients. ANOVA showed differences in birth and follow-up head circumferences. Head circumference was smaller in 1T, compared to 2T. Motor performance was classified as below the fifth percentile in AIMS in all children and 1T showed lower scores in prone, sitting, and total AIMS score, compared to 2T. Children ranged from 8 to 78% on GMFM-A and there was a poorer motor performance of 1T. Nineteen children showed hypertonia, six showed normal tone and six showed hypotonia. Birth head circumference was correlated with AIMS prone postural control. Follow-up head circumference was correlated to prone, supine and total AIMS scores. Smaller head circumference at birth and follow-up denoted poorer postural control. Discussion: Children with congenital Zika syndrome showed microcephaly at birth and follow-up. Smaller head circumferences and poorer motor outcomes were observed in 1T. Infants showed poor visual and motor outcomes. Moderate positive correlations between birth and follow-up head circumference and gross motor function were found.


PEDIATRICS ◽  
1981 ◽  
Vol 67 (4) ◽  
pp. 502-505 ◽  
Author(s):  
Evelyn Lipper ◽  
Kwang-Sun Lee ◽  
Lawrence M. Gartner ◽  
Bruce Grellong

The relative importance of (1) birth weight, gestational age, and head circumference at birth, and (2) appropriateness of birth weight and head circumference to gestational age in the predictability of neurobehavioral outcome was evaluated in 127 low-birth-weight infants at 7 months of age. Lower absolute birth weights, shorter gestational ages, and smaller head circumferences at birth correlated with poorer outcome (Bayley Scales of Infant Development and abnormal neurologic examination) at the corrected chronologic age of 7 months (r = .28 to .42, all P &lt;.005). The incidence of low scores on the Mental Development Index and of severe neurologic deficit was significantly higher in small head circumference for gestational age infants than in appropriate head circumference for gestational age infants (both, P &lt;.05). In the absence of small head circumference, small for gestational age infants had similar incidences of low Bayley scores and abnormal neurologic examinations as did appropriate for gestational age infants. These observations suggest that head circumference at birth may be the single most important variable for subsequent neurobehavioral outcome, and that both birth weight and gestational age may simply be markers of fetal head growth in their relationship to later outcome.


2017 ◽  
Vol 6 (2) ◽  
pp. 6-11
Author(s):  
Netay Kumer Sharma ◽  
Sankar Narayan Dey ◽  
Md Masudur Rahman ◽  
Akter Zahan ◽  
Mahzabeen Islam ◽  
...  

Determination of gestational age by ultrasound has now become an integral part of maternal antenatal care. Accurate assessment of gestational age by sonography is now essential for obstetric management particularly due to term, preterm and post date management. Timing of elective caesarean delivery and decision whether to consider a fetus at risk for intrauterine growth retardation depends in part on the estimated age. In this study gestational age was determined on the basis of head circumference (HC) and correlation was established between weeks of gestation calculated from LMP. A cross sectional study was carried out in the department of Radiology & Imaging, Mymensingh Medical College Hospital during the period of January 2011 to June 2012. Three hundred ninety seven normal pregnant Bangladeshi women age range from 20 to 36 years with apparently healthy fetuses between 18 to 38 weeks of gestation referred for ultrasonic evaluation of pregnancy profile. Mean age was 29.60 years with standard deviation (SD) +0.67. Aim of this study was to determine relationship between menstrual age and HC. Result of this study may give idea about gestational age calculated by LMP of 397 cases and expressed in weeks. Estimated gestational age was determined by HC evaluated by US and expressed in weeks. Significant positive correlation was found between gestational age measured by HC and LMP. Estimated gestational age measured by HC had very close relation with weeks of gestation(LMP), which is 2 to 3 days less from weeks of gestation (LMP) during 18-38 weeks of gestation variation was only 2 to 4 days less from weeks of gestation (LMP). A strong positive significant correlation (r=0.987, P<0.001) was found between weeks of gestation and predicted gestational age measured from HC. Significant relationship between gestational age measured by LMP with estimated gestational age evaluated by head circumference. CBMJ 2017 July: Vol. 06 No. 02 P: 06-11


Author(s):  
Nishita Shettian ◽  
Nikita Pitty

Background: Several models have been proposed to predict the need for an LSCS. With reference to this, the impact of the size of the fetal head traversing the birth canal is an important determinant of delivery outcomes. We examined the association between the head circumference and mode of delivery and perinatal outcomes, when compared to birth weight predicted by scan.Methods: This was a retrospective study, on 800 electronic delivery records between December 2019 and May 2021. Sociodemographic data, obstetrical parameter, term scan findings of head circumference and estimated fetal weight, and labour and perinatal outcomes were collected and analysed.Results: HC >95th centile was found to be comparatively more predictive and statistically significant compared to EFW >95th centile in the prediction of LSCS, with the most common indication being cephalopelvic disproportion. Prolonged second stage of labour was statistically significant in both cohort A and B, undergoing vaginal delivery. It was also noted that a significant number of newborns in cohort A required NICU admissions, while NICU admissions after emergency LSCS was significantly higher in the cohort B (p=0.0032) though the overall 5 and 10 minute APGAR scores and duration of stay were comparable in the groups classified on basis of EFW and HC.Conclusions: The above statistics observed on an Indian population may aid obstetricians in the planning of the mode of delivery, improve pre-labor counselling and efficient management of mothers of large babies. 


2014 ◽  
Vol 8 (2) ◽  
pp. 68
Author(s):  
Sachin Sudarshan Patil ◽  
Ravindra Baliram Deokar ◽  
Jyoti Rahul Sul ◽  
Sandeep Shivaji Gosavi ◽  
Varsha Pratik Mahajan

Author(s):  
Vidyashree Ganesh Poojari ◽  
Aiswarya Jose ◽  
Muralidhar V. Pai

Abstract Background Sonographic measurement of fetal head circumference (HC) is an essential parameter for the estimation of fetal weight as well as in cases with abnormal fetal head size. Since there is a lack of data, the present study was to assess the accuracy of ultrasonographic estimation of fetal HC and to identify factors that affect the accuracy of fetal HC estimation. Material and Methods A prospective cohort observational study was conducted for a year. Sonographic fetal biometry including HC was performed, and fetal HC was measured postnatally. Measures of accuracy and various factors which affect the accuracy are analyzed. Results Ultrasonographic HC underestimated actual postnatal HC in 87.5% and overestimated actual HC in 12.5%. Sonographic underestimation of HC persisted throughout gestation and became more pronounced as gestational age increased. Error in HC was statistically significant in those with low liquor and anterior placenta and in those who had instrumental delivery. Parity, fetal presentation, and maternal diabetes did not affect the error in ultrasonographic measurement of head circumference. When the HC was beyond 95th centile on ultrasound, the error detected postnatally was significant (− 14 mm vs. − 8 mm), though not statistically significant (p value 0.82). The difference between the sonographic and postnatal HC was also related to the mode of delivery with the highest error seen in those who had instrumental vaginal delivery (p value 0.031). Conclusion The ultrasound estimation of fetal HC is associated with significant underestimation of the actual HC measured postnatally. The error in measuring fetal HC increased in those with advanced gestational age, low liquor, and anterior location of the placenta and in those who had instrumental vaginal delivery. The measurement error may have important implications in specific clinical scenarios like monitoring pregnancy with fetal growth restriction, suspected fetal head growth abnormalities, and labor outcome.


2012 ◽  
Vol 3 (5) ◽  
pp. 211-213
Author(s):  
Dhaval Gandhi ◽  
◽  
Rupesh Masand ◽  
Alok Purohit

2021 ◽  
pp. 1-8
Author(s):  
Man Yan Chung ◽  
Wing Cheong Leung ◽  
Wing Ting Tse ◽  
Yuen Ha Ting ◽  
Kwok Ming Law ◽  
...  

<b><i>Introduction:</i></b> Fetal pleural effusion may require in utero shunting which is associated with procedure-related complications. <b><i>Objective:</i></b> To evaluate the efficacy and complications of the newly designed Somatex shunt in treating fetal pleural effusion. <b><i>Methods:</i></b> Consecutive cases with primary fetal pleural effusion who were treated with the Somatex shunt between 2018 and 2019 were evaluated. Perinatal outcomes and complications were retrospectively analyzed. <b><i>Results:</i></b> There were 6 cases of unilateral and 1 case of bilateral pleural effusion, and hence a total of 8 pleuroamniotic shunting procedures were performed. The median gestational age at diagnosis and shunting was 20.7 and 22.6 weeks, respectively. All 8 procedures were successful, achieving complete in utero drainage. All but one were live births (85.7%) with a median gestational age of 38 weeks. The single case of in utero death occurred 4.7 weeks after successful shunting, and no cause could be identified after autopsy. The rates of preterm birth and premature rupture of membranes were 33.3% (2/6) and 16.7% (1/6), respectively. Four of the 8 procedures (50%) had minor shunt-related complications such as dislodgement and entrapment, occurring at a median of 7.7 weeks after shunting. None of the shunts became blocked. <b><i>Conclusions:</i></b> The Somatex shunt is effective in relieving fetal pleural effusions with good survival rate. Overall, it was a safe instrument, though minor shunt complications occurred.


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