Multiple insecticide resistance in Aedes aegypti (Diptera: Culicidae) populations compromises the effectiveness of dengue vector control in French Guiana

Background In Malaysia, dengue remains a top priority disease and usage of insecticides is the main method for dengue vector control. Limited baseline insecticide resistance data in dengue hotspots has prompted us to conduct this study. The present study reports the use of a map on the insecticide susceptibility status of Aedes aegypti and Aedes albopictus to provide a quick visualization and overview of the distribution of insecticide resistance. Method and results The insecticide resistance status of Aedes populations collected from 24 dengue hotspot areas from the period of December 2018 until June 2019 was proactively monitored using the World Health Organization standard protocol for adult and larval susceptibility testing was conducted, together with elucidation of the mechanisms involved in observed resistance. For resistance monitoring, susceptibility to three adulticides (permethrin, deltamethrin, and malathion) was tested, as well as susceptibility to the larvicide, temephos. Data showed significant resistance to both deltamethrin and permethrin (pyrethroid insecticides), and to malathion (organophosphate insecticide) in all sampled Aedes aegypti populations, while variable resistance patterns were found in the sampled Aedes albopictus populations. Temephos resistance was observed when larvae were tested using the diagnostic dosage of 0.012mg/L but not at the operational dosage of 1mg/L for both species. Conclusion The present study highlights evidence of a potential threat to the effectiveness of insecticides currently used in dengue vector control, and the urgent requirement for insecticide resistance management to be integrated into the National Dengue Control Program.

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The development of predictive tools for pre-emptive dengue vector control: a study of Aedes aegypti abundance and meteorological variables in North Queensland, Australia

Tropical Medicine & International Health ◽

10.1111/j.1365-3156.2010.02592.x ◽

2010 ◽

Vol 15 (10) ◽

pp. 1190-1197 ◽

Cited By ~ 51

Author(s):

Aishah H. Azil ◽

Sharron A. Long ◽

Scott A. Ritchie ◽

Craig R. Williams

Keyword(s):

Aedes Aegypti ◽

Vector Control ◽

Meteorological Variables ◽

Dengue Vector ◽

Predictive Tools ◽

Dengue Vector Control

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Ecological Links Between Water Storage Behaviors and Aedes aegypti Production: Implications for Dengue Vector Control in Variable Climates

EcoHealth ◽

10.1007/s10393-010-0301-6 ◽

2010 ◽

Vol 7 (1) ◽

pp. 78-90 ◽

Cited By ~ 46

Author(s):

H. Padmanabha ◽

E. Soto ◽

M. Mosquera ◽

C. C. Lord ◽

L. P. Lounibos

Keyword(s):

Aedes Aegypti ◽

Vector Control ◽

Water Storage ◽

Dengue Vector ◽

Dengue Vector Control

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Spatial variation of insecticide resistance in the dengue vector Aedes aegypti presents unique vector control challenges

Parasites & Vectors ◽

10.1186/s13071-016-1346-3 ◽

2016 ◽

Vol 9 (1) ◽

Cited By ~ 61

Author(s):

Regan Deming ◽

Pablo Manrique-Saide ◽

Anuar Medina Barreiro ◽

Edgar Ulises Koyoc Cardeña ◽

Azael Che-Mendoza ◽

...

Keyword(s):

Aedes Aegypti ◽

Insecticide Resistance ◽

Spatial Variation ◽

Vector Control ◽

Dengue Vector ◽

Unique Vector

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Temephos Resistance in Aedes aegypti in Colombia Compromises Dengue Vector Control

PLoS Neglected Tropical Diseases ◽

10.1371/journal.pntd.0002438 ◽

2013 ◽

Vol 7 (9) ◽

pp. e2438 ◽

Cited By ~ 68

Author(s):

Nelson Grisales ◽

Rodolphe Poupardin ◽

Santiago Gomez ◽

Idalyd Fonseca-Gonzalez ◽

Hilary Ranson ◽

...

Keyword(s):

Aedes Aegypti ◽

Vector Control ◽

Dengue Vector ◽

Dengue Vector Control

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Efikasi Insektisida Gokilath-S50EC (d,d-transsifenotrin 50 g/l) terhadap Nyamuk Aedes aegypti dengan Metode Pengabutan (Thermal Fogging)

ASPIRATOR - Journal of Vector-borne Disease Studies ◽

10.22435/asp.v10i2.187 ◽

2018 ◽

Vol 10 (2) ◽

pp. 73-82

Author(s):

Firda Yanuar ◽

Willem Sugiharto

Keyword(s):

Polyethylene Glycol ◽

Aedes Aegypti ◽

Vector Control ◽

Time Trial ◽

Experimental Results ◽

Test Results ◽

Dengue Vector ◽

Insecticidal Efficacy ◽

Sample Test ◽

Dengue Vector Control

Dengue vector control is still relying on fogging using insecticides with solar solvents. This causes pollution due to the odors generated and residues left in the environment. It is necessary to look for alternative insecticides that no longer use solar as a solvent but use water such as Gokilath-S50EC. In this experiment, we tested the effectiveness of Gokilath-S50EC (d,d-trans-syphenotrin 50 g/l) with the aim to see the insecticidal efficacy of Aedes aegypti known as DHF vector. The sample test mosquito used is Ae. aegypti which comes from Pangandaran Lokalitbangkes as many as 25 females. Test mosquitoes were exposed to insecticides for 3-5 seconds with a method of fogging. The experimental results showed that mosquitoes tested fainting in the first 30 seconds after exposure to insecticides. The same results were shown when the solvent was added polyethylene-glycol (PEG). This time trial also measured droplet diameters at 1.0 mm and 1.2 mm nozzle with or without PEG. The test results showed that PEG increased the percentage of droplets of ≥ 50 µm in air and made the insecticide reach even further. Gokilath-S50EC insecticides are effective in killing Ae. aegypti by using water solvents, the addition of PEG will increase the reach of insecticides but not affect the effectiveness of insecticides.

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Avaliação da produtividade dos criadouros do Aedes aegypti (L.) e Aedes albopictus (Skuse) através dos dados da vigilância em Parati – RJ.

EntomoBrasilis ◽

10.12741/ebrasilis.v5i3.249 ◽

2012 ◽

Vol 5 (3) ◽

pp. 223-226

Author(s):

Eduardo Dias Wermelinger ◽

Adilson Benedito Almeida ◽

Ciro Villanova Benigno ◽

Aldo Pacheco Ferreira

Keyword(s):

Aedes Aegypti ◽

Vector Control ◽

Urban Environment ◽

Aedes Albopictus ◽

Surveillance Data ◽

Dengue Vector ◽

Tree Holes ◽

Dengue Control ◽

Dengue Vector Control

Esse estudo avaliou a produtividade dos criadouros de Aedes aegypti (Linnaeus) e Aedes albopictus (Skuse) no município de Parati através dos dados da vigilância entomológica obtidos pelos métodos preconizados pelo Programa Nacional de Controle da Dengue (PNCD). O maior número de pupas de A. aegypti foi coletado nos ralos (31%), garrafas e latas (23%); e com A. albopictus o maior número foi nas garrafas, latas (24%) e vasos de planta (21%). Do total de pupas obtidas, 84,3% e 79,3% das pupas de A. aegypti e A. albopictus respectivamente foram coletadas em pequenos reservatórios: garrafas, vasos de plantas, pneus, bromélias, oco de árvores e ralos. Essas produtividades contradizem a literatura e podem ser explicadas pelas limitações de acesso aos grandes reservatórios e falha na capacitação dos agentes. Esse estudo chama atenção para a importância que os pequenos reservatórios podem ter na densidade do vetor no meio urbano nacional e conclui que a metodologia de vigilância entomológica usada tem sido ineficaz para identificar os grandes e mais produtivos criadouros. Essa conclusão sugere que essa ineficácia pode ser um fator importante pelos insucessos no combate a dengue no Brasil. Evaluation of Breeding Productivity from Surveillance Data for Aedes aegypti (Linnaeus) and Aedes albopictus (Skuse) in Parati, RJ, Brazil Abstract. This study evaluated the pupa-productivity of the entomologic surveillance according methodology used by the official Program for Dengue Control in Brazil (PDCB) for Aedes aegypti (Linnaeus) and Aedes albopictus (Skuse) in Parati, RJ, Brazil. The highest number of A. aegypti pupae were found in drains (31%), bottles and cans (23%); and the highest number of A. albopictus pupae were found in bottles and cans (24%), and plant vases (21%). Of the total pupae identified 84.3% and 79.3% of A. aegypti and A. albopictus respectively were collected in small receptacles: bottles, plants vase, tires, bromeliads and tree holes. These productivities are not supported by literature and can be explained by the restrictions of access for the bigger receptacles and lack of training of the agents. The study points out the importance which the small receptacles can have on vector densities in urban environment despite of their productivity and conclude that the entomology surveillance methodology for dengue used in PDCB has no efficacy to identify the bigger and more productive receptacles. This conclusion suggests that this inefficacy can be an important factor for the failures on dengue vector control in Brazil.

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UJI EFEKTIVITAS INFUSA DAUN SIRIH MERAH Piper crocatum ruiz TERHADAP MORTALITAS LARVA Aedes aegypti

Vektora Jurnal Vektor dan Reservoir Penyakit ◽

10.22435/vk.v13i1.4353 ◽

2021 ◽

Vol 13 (1) ◽

pp. 61-66

Author(s):

Riwanti Winandasari ◽

Ritna Udiyani ◽

Tika Sari Dewy ◽

Harninda Kusumaningtyas ◽

Nita Rahayu

Keyword(s):

Experimental Design ◽

Aedes Aegypti ◽

Vector Control ◽

Control Group ◽

Dengue Vector ◽

Endemic Country ◽

Test Room ◽

Betel Leaf ◽

Post Test ◽

Dengue Vector Control

Indonesia is known as a dengue-endemic country with an increasing number of cases. Appropriate dengue vector control efforts are needed to control the transmission of this disease effectively and efficiently. Botanical larvicide is one type of dengue vector control which is expected to be an alternative as a substitute for chemical larvicides. The purpose of this study was to determine the effect of red betel (Piper crocatum)infusion on the mortality of Ae. aegypti. True experimental design with post-test only with control group was used in this study. The test was carried out by dividing the sample into two groups, including the red betel infusion group and the control group (with aquadest), the observations were carried out for 24 hours. The results of the study showed that the larvacide test of red betel leaf infusion had an effect on 12 to 24 hours, and there was an increase in mortality of Ae. egypti for 24 hours. The humidity of the test room is one of the factors that can affect the results of the study. Abstrak Indonesia dikenal sebagai negara endemis dengue dengan jumlah kasus yang terus meningkat. Appropriate dengue vector control efforts diperlukan untuk mengendalikan penularan penyakit ini secara efektif dan efisien. Larvasida botani merupakan salah satu jenis pengendalian vektor dengue yang diharapkan dapat menjadi alternatif sebagai pengganti larvasida kimia. Tujuan penelitian ini untuk mengetahui pengaruh infusa sirih merah (Piper crocatum) terhadap mortalitas larva Ae. aegypti. True eksperimen design dengan post test only with control group digunakan dalam penelitian ini. Pengujian dilakukan dengan membagi menjadi dua kelompok sampel, meliputi kelompok infusa sirih merah dan kelompok kontrol (dengan Aquadest), pengamatan dilakukan selama 24 jam. Hasil studi menunjukkan Uji larvasida infusa daun sisrih merah berpengaruh pada 12 sampai dengan 24 jam, dan terdapat peningkatan mortalitas larva Ae. egypti selama 24 jam. Kelembaban ruangan uji menjadi salah satu faktor yang dapat mempengaruhi hasil studi.

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