Levels of organochlorine pesticides in the blood serum of agricultural workers from Rio de Janeiro State, Brazil

Serum levels of organochlorine pesticides (OCP) were measured in agricultural workers from Rio de Janeiro State, Brazil. Blood samples from 26 volunteers (24 males, 02 females, 17-60 years old) were taken in October 1997. OCP residues (op'DDT pp'DDT, pp'DDD, pp'DDE, aldrin, dieldrin, endrin, heptachlor, heptachlor-epoxide, alpha-, beta- and gamma-hexachlorocyclohexane, and hexachlorobenzene) were analyzed by gas chromatography with an electron capture detector. Tests detected pp'DDE in 16 out of 26 samples, but pp'DDE concentration exceeded 1.4 µg/L (i.e. 1.8, 2.4 and 4.4 µg/L) in only 3 of these. beta-HCH was found in 6 (23.1%) out of 26 samples. In one sample beta-HCH did not exceed 1.4 µg/L, but in the remaining samples concentrations ranged from 1.4 to 5.3 µg/L. The percentage of positive pp'DDE samples increased from the youngest (£29 yrs: 30.0%) to the oldest age group (³ 40 yrs: 100%). A similar trend was found for beta-HCH contamination (£ 29 yrs: 0%; 30-39 yrs: 20.0%; ³40 yrs: 66.7%). Dieldrin (3.7 µg/L) was found in only one sample. No other OCP residue was found in the samples. Serum concentrations of OCPs found in this study are comparable to levels reported for the non-occupationally exposed population in Brazil and elsewhere.

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Serum levels of organochlorine pesticides and polychlorinated biphenyls among inhabitants of Greater Metropolitan Rio de Janeiro, Brazil

Cadernos de Saúde Pública ◽

10.1590/s0102-311x2002000200017 ◽

2002 ◽

Vol 18 (2) ◽

pp. 519-524 ◽

Cited By ~ 20

Author(s):

Isabella Fernandes Delgado ◽

Heloisa H.C. Barretto ◽

Teresa A. Kussumi ◽

Irene Baptista Alleluia ◽

Cenira de A. Baggio ◽

...

Keyword(s):

Detection Limit ◽

Polychlorinated Biphenyls ◽

Organochlorine Pesticides ◽

Rio De Janeiro ◽

Serum Lipids ◽

Serum Levels ◽

Electron Capture Detection ◽

Persistent Organochlorine ◽

Alpha Beta ◽

Janeiro City

Levels of persistent organochlorine pesticides (OCPs) and polychlorinated biphenyls (PCBs) were determined in the blood serum of people living and working in the urban area of greater Rio de Janeiro city. Blood samples from 33 volunteers (16 males, 17 females, 19-63 years old) were taken in January 1999. OCP residues (op'DDT, pp'DDT, pp'DDD, pp'DDE, Aldrin, Dieldrin, Endrin, Heptachlor, Heptachlor-epoxide, alpha-, beta- and gamma-Hexachlorocyclo-hexane, Hexachlorobenzene) and PCBs (congeners: 28, 52, 101, 138, 153, 180) were extracted with n-hexane and analyzed by gas chromatography with electron capture detection. Except for pp'DDE (detection limit = 1.4µg/L) no other OCP residue was found in the samples. No PCB congener (detection limit = 2.0µg/L) was detected either. pp'DDE was found in 17 out of 33 samples in concentrations that ranged from 1.4 to 8.4 µg/L of serum or, on a fat basis, from 0.200 to 3.452 µg/g of serum lipids. Percentage of positive samples (%) and levels of pp'DDE (range of positive samples) increased from the youngest to the oldest group (<=29 yrs: 10%, 0.278µg/g; 30-39 yrs: 60%, 0.200-0.765µg/g; > or = 40 yrs: 77%, 0.257-3.452µg/g).

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Organochlorine pesticides in marine tucuxi dolphin milk incidentally captured with its calf in Barra de São João, east coast of Rio de Janeiro State, Brazil

Marine Biodiversity Records ◽

10.1017/s1755267209000530 ◽

2009 ◽

Vol 2 ◽

Cited By ~ 1

Author(s):

J.F. de Moura ◽

S. Siciliano ◽

P.N. Sarcinelli ◽

S. Hacon

Keyword(s):

Organochlorine Pesticides ◽

Rio De Janeiro ◽

East Coast ◽

Janeiro State

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Sex Ratio and Organochlorine Pesticides: Time Series of 55 Years in an Exposed Population in Rio de Janeiro/Brazil

Epidemiology ◽

10.1097/01.ede.0000362756.79347.25 ◽

2009 ◽

Vol 20 ◽

pp. S225-S226

Author(s):

Raphael Guimarães ◽

Armando Meyer ◽

Claudia Coeli ◽

Carmen Asmus

Keyword(s):

Time Series ◽

Sex Ratio ◽

Organochlorine Pesticides ◽

Rio De Janeiro ◽

Exposed Population

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Environmental exposure to benzene: evaluation of urinary S-PMA and polymorphism (CYP2E1-1293G>C and NQO1 609C>T) in Campos Elíseos residents, Duque de Caxias, Rio de Janeiro State, Brazil

Cadernos de Saúde Pública ◽

10.1590/0102-311x00198618 ◽

2019 ◽

Vol 35 (7) ◽

Author(s):

Cristiane Barata Silva ◽

Caroline de Lima Mota ◽

Yasmin Rocha Almeida ◽

Vanessa Emídio ◽

Antonio Sergio A. Fonseca ◽

...

Keyword(s):

Environmental Contamination ◽

Rio De Janeiro ◽

Local Population ◽

Oil Refinery ◽

International Agency ◽

Industrial Complex ◽

Genotype Frequencies ◽

Exposed Population ◽

Hematological Changes ◽

Janeiro State

Benzene is one of the most important substances for assessment, due to its significant use, the environmental contamination resulting from its emission and the effects on human health. It is classified by the International Agency for Research on Cancer (IARC) as a known carcinogen to humans (group 1) and associated with the development of leukemia. In general, the population is exposed to this substance by inhaling contaminated air, which varies according to the location and intensity of its potential sources. The petrochemical industry is one of the most important sources of this compound. The municipality of Duque de Caxias, specifically the Campos Elíseos district, in Rio de Janeiro State, Brazil, houses the Industrial Complex of Campos Elíseos (PICE), a grouping of over 25 industries, which includes the second largest oil refinery in Brazil. Environmental contamination from the PICE has been recognized, but there is a lack of studies concerning its impact on the health of the surrounding population. S-phenylmercapturic acid (S-PMA) concentrations ranging from 0.80 to 8.01μg.g-1 creatinine were observed in the local population, apparently related to hematological changes also observed in exposed population. The quantifiable presence of urinary S-PMA from the benzene metabolism is associated with the fact that 60% of the participants present specific hematological changes, which may be due to the environmental benzene exposure. The allele and genotype frequencies of the CYP2E1 and NQO1 enzymes observed in the study population were similar to those reported in other studies. The presence of the variant allele in the NQO1 genotype may be a risk factor for the observed hematological changes.

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Organochlorines in Chinese Women: Determinants of Serum Concentrations

Advanced Materials Research ◽

10.4028/www.scientific.net/amr.183-185.1513 ◽

2011 ◽

Vol 183-185 ◽

pp. 1513-1516

Author(s):

Wu Wen Lv

Keyword(s):

Heavy Metals ◽

Serum Level ◽

Organochlorine Pesticides ◽

Organic Pollutants ◽

Chinese Women ◽

Serum Levels ◽

High Serum ◽

Environmental Chemicals ◽

Serum Concentrations ◽

High Serum Level

People are frequently exposed to various environmental chemicals such as organic pollutants, heavy metals, etc. Therefore, the aim of this paper is to investigate the accumulation level of organochlorines in women from Qiqihaer city in china. Of the 160 people investigated, 113 sujects were detected with different serum levels of organochlorine pesticides (range: 0.042 - 33.072 μg/L). Moreover, the results indicated that there was high serum level of accumulated organochlorines pesticides of women in Chinese, and the serum concentrations of organochlorines pesticides was associated with age.

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METABOLISM OF ANDROSTENEDIONE IN SKIN AND SERUM LEVELS OF GONADOTROPHINS AND ANDROGENS IN PREPUBERTAL BOYS WITH HYPOSPADIAS

Journal of Endocrinology ◽

10.1677/joe.0.0760399 ◽

1978 ◽

Vol 76 (3) ◽

pp. 399-409 ◽

Cited By ~ 11

Author(s):

JAN SVENSSON ◽

PETER ENEROTH ◽

JAN-ÅKE GUSTAFSSON ◽

MARTIN RITZÉN ◽

ÅKE STENBERG

Keyword(s):

Reductase Activity ◽

Serum Levels ◽

Congenital Defect ◽

Age Group ◽

Serum Concentrations ◽

Male Urethra ◽

Control Subjects ◽

Prepubertal Boys ◽

Group 1

The metabolism of 4-[1,2-3H]androstene-3,17-dione in the prepuce, axillary skin and skin from the arm was investigated in 27 boys operated for phimosis (controls) and 13 unselected boys with hypospadias (a congenital defect of the male urethra). In all types of skin investigated, androstenedione was metabolized to 5α-androstane-3,17-dione, 3α-hydroxy-5α-androstan-17-one, 3β-hydroxy-5α-androstan-17-one and testosterone. Conversion to testosterone was found in the prepuce of two out of 11 boys with hypospadias. Mild forms of hypospadias in the age group 1–4 years had a higher level of 5α-reductase activity in the prepuce than controls in the same age group (P < 0·05); no such differences were found in the few severe cases of hypospadias in this group. No other differences in 5α-reductase activity were found between hypospadic boys and controls. The ratio of 5α-reductase activity in the prepuce: 5α-reductase activity in skin from the arm was significantly higher (P<0·05) in hypospadic boys than in controls in the age group 1–4 years. Serum levels of LH and FSH were the same in normal and hypospadic boys but the concentration of prolactin in the serum was lower in boys with hypospadias compared with control subjects in the age group 1–4 years (P<0·005). No differences were found in serum concentrations of androstenedione, testosterone, oestradiol and testosterone-binding globulin.

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Population structure of the crab Callinectes ornatus Ordway, 1863 (Brachyura: Portunidae) bycatch in shrimp fishery in northern Rio de Janeiro state, Brazil

Biota Neotropica ◽

10.1590/s1676-06032012000100007 ◽

2012 ◽

Vol 12 (1) ◽

pp. 93-98 ◽

Cited By ~ 6

Author(s):

Caroline Cabral Tudesco ◽

Laís Pinho Fernandes ◽

Ana Paula Madeira Di Beneditto

Keyword(s):

Population Structure ◽

Rio De Janeiro ◽

Carapace Width ◽

Age Group ◽

Shrimp Fishery ◽

First Maturity ◽

Janeiro State ◽

Over Time ◽

Swimming Crabs ◽

Size At First Maturity

This study provides the first data on the population structure of swimming crab Callinectes ornatus Ordway, 1863 bycatch from coastal shrimp fishing in northern Rio de Janeiro State, Brazil (21º 30'-21º 50' S and 41º 05'-41º 07' W). Crabs were collected monthly from April 2006 to March 2007. A total of 5,611 specimens were analyzed, of which 3,951 were males and 1,660 ovigerous and non-ovigerous females. The overall sex ratio (2:1) differ significantly from the expected 1:1 proportion, being the mature males significantly predominant as bycatch in this fishery. The specimens' carapace width and weight varied from 27 to 126 mm (mean: 77.3 ± 12.3 mm) and 1.2 to 128.2 g (mean: 31.0 ± 14.4 g) for males, and 30 to 101 mm (mean: 63.4 ± 9.3 mm) and 1.7 to 66.0 g (mean: 16.4 ± 7.4 g) for ovigerous and non-ovigerous females. Seasonal comparisons did not reveal differences between the number of specimens captured in dry and rainy periods considering both sexes and maturity stages. The size at first maturity was 79 mm for males and 65 mm for females, and the carapace width-weight relationship indicated an alometric pattern for both sexes. The bycatch swimming crabs are locally used as bait, but the capture tendency for a specific sex/age-group can affect this population structure over time.

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