scholarly journals Illness uncertainty and treatment motivation in type 2 diabetes patients

2007 ◽  
Vol 15 (4) ◽  
pp. 575-582 ◽  
Author(s):  
João Luís Alves Apóstolo ◽  
Catarina Sofia Castro Viveiros ◽  
Helena Isabel Ribeiro Nunes ◽  
Helena Raquel Faustino Domingues

AIMS: To characterize the uncertainty in illness and the motivation for treatment and to evaluate the existing relation between these variables in individuals with type 2 diabetes. METHOD: Descriptive, correlational study, using a sample of 62 individuals in diabetes consultation sessions. The Uncertainty Stress Scale and the Treatment Self-Regulation Questionnaire were used. RESULTS: The individuals with type 2 diabetes present low levels of uncertainty in illness and a high motivation for treatment, with a stronger intrinsic than extrinsic motivation. A negative correlation was verified between the uncertainty in the face of the prognosis and treatment and the intrinsic motivation. DISCUSSION: These individuals are already adapted, acting according to the meanings they attribute to illness. Uncertainty can function as a threat, intervening negatively in the attribution of meaning to the events related to illness and in the process of adaptation and motivation to adhere to treatment. Intrinsic motivation seems to be essential to adhere to treatment.

2017 ◽  
Vol 8 ◽  
Author(s):  
Melissa J. Blumenthal ◽  
Sylvia Ujma ◽  
Arieh A. Katz ◽  
Georgia Schäfer

2018 ◽  
Vol 62 (2) ◽  
Author(s):  
Carlos Kornhauser ◽  
Gloria Barbosa-Sabanero ◽  
Noemí Gutierrez-Romero ◽  
Myrna Sabanero ◽  
Elva L. Perez-Luque ◽  
...  

The beneficial effects of a short period of Telmisartan administration were successfully assessed trough pentosidine urinary levels (uPen) and urinary podocyte excretion (UPE), in type 2 diabetes mellitus (DM2) patients. Patients with podocyturia received Telmisartan treatment (80 mg/day) for two months.  uPen were quantified pre and post treatment using HPLC with fluorimetric detection and in-lab synthesized standard. Immunofluorescence method for podocalyxin was used to evaluate urinary excretion of podocytes. uPen and UPE significantly decrease after treatment (p<0.01255 and p<0.005 respectively), as well as serum total cholesterol and LDL levels (p<0.001). These results suggest that podocyte protection by Telmisartan even in the face of deficient metabolic control could be an important matter in the prevention and progression of diabetic nephropathy. This study also strengthens evidence of the promising role of pentosidine as prognostic and diagnostic markers in diabetic nephropathy


Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 826-P
Author(s):  
YAGUANG ZHENG ◽  
KATIE WEINGER ◽  
MATT C. GREGAS ◽  
JORDAN GREENBERG ◽  
ZHUOXIN LI ◽  
...  

2009 ◽  
Vol 10 (3) ◽  
pp. 187 ◽  
Author(s):  
Myeong Hee Hong ◽  
Joo Wha Yoo ◽  
Mee Ock Gu ◽  
Soon Ai Kim ◽  
Jeong Rim Lee ◽  
...  

2007 ◽  
Vol 66 (3) ◽  
pp. 451-457 ◽  
Author(s):  
D. B. Dunger ◽  
B. Salgin ◽  
K. K. Ong

Size at birth and patterns of postnatal weight gain have been associated with adult risk for the development of type 2 diabetes in many populations, but the putative pathophysiological link remains unknown. Studies of contemporary populations indicate that rapid infancy weight gain, which may follow fetal growth restriction, is an important risk factor for the development of childhood obesity and insulin resistance. Data from the Avon Longitudinal Study of Pregnancy and Childhood shows that rapid catch-up weight gain can lead to the development of insulin resistance, as early as 1 year of age, in association with increasing accumulation of central abdominal fat mass. In contrast, the disposition index, which reflects the β-cells ability to maintain insulin secretion in the face of increasing insulin resistance, is much more closely related to ponderal index at birth than postnatal catch-up weight gain. Infants with the lowest ponderal index at birth show a reduced disposition index at aged 8 years associated with increases in fasting NEFA levels. The disposition index is also closely related to childhood height gain and insulin-like growth factor-I (IGF-I) levels; reduced insulin secretory capacity being associated with reduced statural growth, and relatively short stature with reduced IGF-I levels at age 8 years. IGF-I may have an important role in the maintenance of β-cell mass, as demonstrated by recent studies of pancreatic β-cell IGF-I receptor knock-out and adult observational studies indicating that low IGF-I levels are predictive of subsequent risk for the development of type 2 diabetes. However, as insulin secretion is an important determinant of IGF-I levels, cause and effect may be difficult to establish. In conclusion, although rapid infancy weight gain and increasing rates of childhood obesity will increase the risk for the development of insulin resistance, prenatal and postnatal determinants of β-cell mass may ultimately be the most important determinants of an individual's ability to maintain insulin secretion in the face of increasing insulin resistance, and thus risk for the development of type 2 diabetes.


2008 ◽  
Vol 2 (1) ◽  
pp. 48-62 ◽  
Author(s):  
Helen Altman Klein ◽  
Katherine D. Lippa

People with type 2 diabetes risk disability and early death when they fail to control their blood glucose levels. Despite advances in medicine, pharmacology, human factors, and education, dangerous glucose levels remain endemic. To investigate cognitive barriers to control, we observed American Diabetes Association (ADA) certified training programs; reviewed ADA and National Institute of Health diabetes Web sites; and interviewed patients with type 2 diabetes using a critical decision method. A consistent picture emerged. The prevailing rules and procedures approaches are not preparing patients for the dynamic control task they face. Patients are often unable to understand and use the rules and procedures provided. They are unprepared to detect problems, make sense of dynamic relationships, and manage complex situations. Our results suggest that glucose self-regulation is better conceptualized as a dynamic control challenge requiring complex processes, including problem detection, sensemaking, decision making, and planning/replanning. The mismatch between most patient training and the dynamic demands of glucose regulation helps explain limitations in existing training and poor patient outcomes. We argue that constructs gleaned from naturalistic decision-making research in other complex domains can help many but not all patients develop the cognition necessary for effective blood glucose self-management.


2015 ◽  
Vol 32 (11) ◽  
pp. 1504-1512 ◽  
Author(s):  
M. L. Tanenbaum ◽  
H. Leventhal ◽  
J. Y. Breland ◽  
J. Yu ◽  
E. A. Walker ◽  
...  

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