High prevalence of arterial hypertension in a Brazilian Northeast population of low education and income level, and its association with obesity and metabolic syndrome

Metabolic syndrome (MS) is considered an age-associated pathology, often combined with hypertension (AH) and has a high prevalence in the elderly. However, a comparative study of the broad spectrum of proinflammatory and anti-inflammatory interleukins with an assessment of their informative value in elderly patients WITH MS with AH was not carried out. The aim of the study was to improve the diagnosis of MS with hypertension in elderly patients based on the analysis of the informativity of serum interleukins.. The content of interleukins in serum was studied in 86 patients with MS and AH aged 60-75 years and 35 persons without MS and AH, comparable in age and sex. It was found that for the diagnosis of MS in combination with AH as the leading laboratory markers of systemic immunity it is necessary to use highly informative IL-8, IL-1B, IL-4 and IL-10. Other serum interleukins (Il-6, IL-2, TNF-α, interferon-ɣ, interferon-α and IL-18) can be considered as additional markers in the diagnosis of MS with hypertension in the elderly.

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PREVALENCE AND TIME OF DEVELOPMENT OF SYSTEMIC ARTERIAL HYPERTENSION IN PATIENTS AFTER LIVER TRANSPLANTATION

Arquivos de Gastroenterologia ◽

10.1590/s0004-2803.202100000-13 ◽

2021 ◽

Vol 58 (1) ◽

pp. 77-81

Author(s):

Bianca de Oliveira LEMOS ◽

Rita de Cássia Martins Alves SILVA ◽

Renato Ferreira da SILVA

Keyword(s):

Metabolic Syndrome ◽

Liver Transplantation ◽

Arterial Hypertension ◽

Calcineurin Inhibitors ◽

Immunosuppressive Drugs ◽

Immunosuppressive Drug ◽

University Hospital ◽

Post Transplantation ◽

Systemic Arterial Hypertension ◽

High Prevalence

ABSTRACT BACKGROUND: The use of immunosuppressive drugs after liver transplantation (LT) is associated with the development of systemic arterial hypertension (SAH), in addition to other comorbidities of metabolic syndrome. OBJECTIVE: Therefore, the purpose of this study was to analyze the time after use immunosuppressive drugs the patient progresses to SAH, as well as to identify its prevalence and the factors that may be correlated to it. METHODS: A retrospective and longitudinal study was conducted, based on the analysis of medical records of 72 normotensive patients, attended in the transplant unit of a university hospital, between 2016 and 2019. RESULTS: It was observed, on average, 9±6.98 months after immunosuppressive use, the patients were diagnosed with hypertension, and the prevalence of transplanted patients who evolved to SAH in this study was 59.64% (41 patients). In addition, there was a correlation between serum dosage of tacrolimus and the development of SAH (P=0.0067), which shows that tacrolimus has a significant role in the development of SAH. Finally, it was noticed that the development of post-transplantation hypertension indicates a higher risk of the patient presenting the other parameters of metabolic syndrome, as well as a higher impairment in its renal function (P=0.0061). CONCLUSION: This study shows that the patients evolved to SAH in an average of 9±6.98 months after immunosuppressive drug use. We have also found high prevalence of systemic arterial hypertension (59.64%) in patients after liver transplantation, who used calcineurin inhibitors, especially when associated with the use of tacrolimus.

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Metabolic Syndrome and Prediabetes Fail to Detect a High Prevalence of Early Insulin Resistance—The PREMIER Study

Diabetes ◽

10.2337/db18-1534-p ◽

2018 ◽

Vol 67 (Supplement 1) ◽

pp. 1534-P

Author(s):

DAVID P. CISTOLA ◽

ALOK K. DWIVEDI ◽

JAMY D. ARD

Keyword(s):

Insulin Resistance ◽

Metabolic Syndrome ◽

High Prevalence

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ARTERIAL HYPERTENSION AND COMORBIDITY (REVIEW)

JOURNAL OF CARDIORESPIRATORY RESEARCH ◽

10.26739/2181-0974-2020-2-1 ◽

2020 ◽

Vol 2 (1) ◽

pp. 9-13

Author(s):

Irina Agababyan ◽

◽

Shukhrat Ziyadullaev ◽

Jamshid Ismailov

Keyword(s):

Quality Of Life ◽

Metabolic Syndrome ◽

Arterial Hypertension ◽

The Metabolic Syndrome

Today, hypertension is considered by many authors within the framework of the manifestation of the metabolic syndrome. It has been established that in persons with hypertension in 60% of cases, various variants of MS are found. In addition, hypertension is a factor that reduces the quality of life of patients, especially those with comorbid pathology

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Role of genetic factors in the development of hypertension in young patients with metabolic syndrome

Spravočnik vrača obŝej praktiki (Journal of Family Medicine) ◽

10.33920/med-10-2004-03 ◽

2020 ◽

pp. 23-32

Author(s):

Elena Korneeva ◽

Mikhail Voevoda ◽

Sergey Semaev ◽

Vladimir Maksimov

Keyword(s):

Metabolic Syndrome ◽

High Risk ◽

Arterial Hypertension ◽

Genetic Factors ◽

Young Patients ◽

Integrin Αiibβ3 ◽

Ace Gene ◽

The Metabolic Syndrome

Results of the study related to polymorphism of ACE gene (rs1799752)‎, integrin αIIbβ3, and CSK gene (rs1378942) influencing development of arterial hypertension in young patients with metabolic syndrome are presented. Hypertension as a component of the metabolic syndrome was detected in 15.0% of young patients. Prevalence of mutant alleles of the studied genes among the examined patients was quite high, so homozygous DD genotype was found in 21.6%, and mutant D allele of the ACE gene in 47.4%. A high risk of hypertension in patients with MS was detected in carriers of the T allele of the CSK (rs1378942) gene – 54.8%, which was most often observed in a combination of polymorphic ACE and CSK gene loci (p = 0.0053).

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High prevalence of the metabolic syndrome in hypertensive rural Chinese women

Acta Cardiologica ◽

10.2143/ac.63.5.2033226 ◽

2008 ◽

Vol 63 (5) ◽

pp. 591-598 ◽

Cited By ~ 1

Author(s):

X. Zhang ◽

Z. Sun ◽

D. Zhang ◽

L. Zheng ◽

S. Liu ◽

...

Keyword(s):

Metabolic Syndrome ◽

Chinese Women ◽

The Metabolic Syndrome ◽

High Prevalence

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SAT0073 Arterial Hypertension In Rheumatoid Arthritis Without Cardiovascular Disease: High Prevalence, Low Awareness, Poor Control And Increased Vascular Damage-Associated “White Coat” Phenomenon

Annals of the Rheumatic Diseases ◽

10.1136/annrheumdis-2013-eular.1799 ◽

2013 ◽

Vol 72 (Suppl 3) ◽

pp. A604.2-A604

Author(s):

A. Protogerou ◽

E. Zampeli ◽

G. D. Konstantonis ◽

K. Arida ◽

D. B. Panagiotakos ◽

...

Keyword(s):

Rheumatoid Arthritis ◽

Cardiovascular Disease ◽

Arterial Hypertension ◽

Vascular Damage ◽

White Coat ◽

Poor Control ◽

High Prevalence

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The Prevalence and Predictors of Hypertension and the Metabolic Syndrome in Police Personnel

International Journal of Environmental Research and Public Health ◽

10.3390/ijerph18136728 ◽

2021 ◽

Vol 18 (13) ◽

pp. 6728

Author(s):

James D. Yates ◽

Jeffrey W. F. Aldous ◽

Daniel P. Bailey ◽

Angel M. Chater ◽

Andrew C. S. Mitchell ◽

...

Keyword(s):

Metabolic Syndrome ◽

Density Lipoprotein ◽

Cross Sectional ◽

Job Type ◽

The Metabolic Syndrome ◽

High Prevalence ◽

Police Personnel ◽

Behavioural Factors ◽

Cardiometabolic Risk Markers ◽

Police Forces

Hypertension and metabolic syndrome (METSYN) are reportedly high in police forces. This may contribute to health deterioration and absenteeism in police personnel. Police forces comprise of staff in ‘operational’ and ‘non-operational’ job types but it is not known if job type is associated to hypertension and METSYN prevalence. This study aimed to explore the prevalence of hypertension and METSYN, the factors associated with the risk of hypertension and METSYN, and compare physiological, psychological, and behavioural factors between operational and non-operational police personnel. Cross-sectional data was collected from 77 operational and 60 non-operational police workers. Hypertension and METSYN were prevalent in 60.5% and 20% of operational and 60.0% and 13.6% of non-operational police personnel, respectively (p > 0.05). Operational job type, moderate organisational stress (compared with low stress) and lower high-density lipoprotein cholesterol were associated with lower odds of hypertension, whereas increasing body mass index was associated with increased odds of hypertension (p < 0.05). None of the independent variables were significantly associated with the odds of METSYN. Operational police had several increased cardiometabolic risk markers compared with non-operational police. Given the high prevalence of hypertension and METSYN in operational and non-operational personnel, occupational health interventions are needed for the police and could be informed by the findings of this study.

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