scholarly journals Double rhomboidal flap for reconstruction of large surgical defect of the labial commissure

2012 ◽  
Vol 87 (3) ◽  
pp. 456-458 ◽  
Author(s):  
Pedro Andrade ◽  
Ana Brinca ◽  
Ricardo Vieira ◽  
Américo Figueiredo

Closure of perioral surgical defects involving the oral commissures is highly challenging. We describe a 69-year-old male patient with a large basal cell carcinoma of the right perioral region, extending to the right oral commissure. This lesion was radically excised, and the resulting surgical defect was closed using a homolateral double opposing rhomboidal flap. The final result was esthetically very satisfactory, with total preservation of lip function. Double opposing rhomboidal flaps are viable surgical options for the reconstruction of surgical defects involving the perioral area and oral commissures. In this relatively simple procedure, donor skin is obtained from the nearby cheek and mandibular areas, under low risk of surgical complications, preserving lip function without distortion of the labial anatomy.

2020 ◽  
Author(s):  
Dalin Feng ◽  
Mingshuai Wang ◽  
Xiaodong Zhang ◽  
Jianwen Wang

Abstract Background The objective of this study is to discuss clinical characteristics and treatments of hereditary leiomyomatosis renal cell carcinoma on the basis of 2 cases and to review recent literature, in order to present medical advances. Methods A 29-year old male patient came to our hospital because of a huge tumour on the right kidney. Enhanced CT showed that the tumour was about 15.5*10.5 cm, and was considered to be malignant. Another case was a 38-year old female patient. She complained was found to have a right kidney tumour in a routine physical examination. Enhanced CT showed an early-stage tumour of about 4.3*3.7 cm on the lower pole of the right kidney. The male patient underwent open radical nephrectomy and the female patient underwent laparoscopic radical nephrectomy and extensive retroperitoneal lymph node dissection. The two patients underwent genetic testing and were diagnosed as having hereditary leiomyomatosis with renal cell carcinoma. Results The postoperative pathology in both patients revealed type 2 papillary renal cell carcinoma but with different prognosis. The male patient suffered multiple metastasis 10 months post-operation. The metastatic tumour of the abdominal wall was resected to confirm recurrence and hereditary leiomyomatosis renal cell carcinoma was diagnosed by the genetic test. While the female patient had a specific family history and uterine leiomyomas, the genetic test helped us to identify hereditary leiomyomatosis renal cell carcinoma pre-operation. Because of the early diagnosis and timely treatment, the female patient was considered to have a good prognosis. Conclusion Hereditary leiomyomatosis renal cell carcinoma is a rare hereditary disease resulting from FH gene mutation. There are currently no effective treatments.Our cases demonstrate that hereditary leiomyomatosis renal cell carcinoma is a very aggressive disease. Early screening and surveillance are recommended for patients with a family history or who are at risk of hereditary leiomyomatosis renal cell carcinoma. Surgical and palliative therapy still play an important role in clinical treatment.


2003 ◽  
Vol 30 (3) ◽  
pp. 250-251 ◽  
Author(s):  
Kiyomi Matsushita ◽  
Akira Kawada ◽  
Yoshinori Aragane ◽  
Tadashi Tezuka

2013 ◽  
Vol 39 (5) ◽  
pp. 609-614
Author(s):  
Sema Murat ◽  
Ayhan Gurbuz ◽  
Kivanc Kamburoglu

This case report details a 65-year-old male patient who underwent mandibular resection and radiotherapy as treatment for squamous cell carcinoma of the right mandible. The patient was rehabilitated with an implant-supported fixed partial denture and a maxillary occlusal ramp. The patient has been wearing his prosthesis for 2 years with no complaints.


2021 ◽  
Vol 79 (3) ◽  
pp. 261-264
Author(s):  
Luísa Rolim ◽  
Bruno M. Fernandes ◽  
Carolina Carvalho ◽  
António Silva ◽  
Joana Calvão ◽  
...  

Basal cell carcinoma is the most common skin cancer, with a very low incidence of metastases, associated with high morbidity and mortality. The morpheaform clinical variant is uncommon, presenting an aggressive growth pattern. Early diagnosis and new targeted therapies for metastatic disease are important to improve survival rates. We present the case of a 29-year-old patient with morpheaform basal cell carcinoma in the right genian region. Due to local recurrences, he underwent surgery and adjuvant radiotherapy. For extensive metastatic bone involvement, the patient started vismodegib and, later, pembrolizumab, and also performed palliative radiotherapy. Despite several lines of systemic therapy, the disease progressed, and the patient died after 8 years of follow-up. This case shows how crucial it is to identify risk factors for metastatic basal cell carcinoma and highlights the need to improve target therapies and tailor them to the patient’s biological profile.


2011 ◽  
Vol 2 (4) ◽  
pp. 342-345
Author(s):  
Vinod Kumar ◽  
Chaitanya Babu ◽  
Geetanshu Dawar

ABSTRACT Here, we report a case of keratocystic odontogenic tumor occurring bilaterally in a male patient in fourth decade of life. This case is different from bilateral lesions of keratocystic odontogenic tumor which are most commonly parakeratinized and are associated with syndromes like nevoid basal cell carcinoma syndrome. In our case, we could not find out any syndromic association and furthermore histopathology was in line of orthokeratinization.


2017 ◽  
Vol 5 (4) ◽  
pp. 497-500
Author(s):  
Cristiana Voicu ◽  
Mara Mihai ◽  
Mihai Lupu ◽  
James W. Patterson ◽  
Nely Koleva ◽  
...  

BACKGROUND: Basal cell carcinoma (BCC) is the most frequently encountered neoplasm worldwide. While nodular BCC is the most frequent clinical subtype, other forms of BCC, such as superficial, cystic, morpheiform, infiltrative, and pigmented may also be encountered.CASE PRESENTATION: We present the case of a 67-year-old male with a relatively well-defined infiltrative, pigmented plaque with multiple colours and peripheral growth situated in the right axillary region. The histopathologic examination performed after complete surgical excision of the tumour revealed a complex pigmented BCC with macronodular, fibroepithelioma-like, cystic, focally infiltrative and basosquamous features.CONCLUSION: Uncommon locations of BCCs in sun-protected areas such as the axillary region require a higher degree of suspicion for diagnosis. The complex histology of the presented case, including subtypes with differing biologic attributes, emphasises the importance of histopathological examination in the diagnosis and therapeutic management of BCC.


2019 ◽  
Vol 11 (2) ◽  
pp. 145-149
Author(s):  
Usho Go ◽  
Kazunori Miyata ◽  
Masaru Fujita ◽  
Takashi Ohide ◽  
Tsuyoshi Mitsuishi

We herein present a case of annular basal cell carcinoma (BCC) with spontaneous regression on the right temporal region of a 56-year-old Japanese male. Histopathological examination revealed that the central section had no tumor cells. The sweat glands, follicles, and other cutaneous appendages were also absent. This pattern of spontaneous regression is quite uncommon, and understanding the histopathology may be important for future approaches to BCC.


Author(s):  
Oktay Avcı ◽  
Uğur Pabuççuoğlu ◽  
M. Ali Koçdor ◽  
Mehtat Ünlü ◽  
Çiler Akin ◽  
...  

Author(s):  
Hiba Chaudhry ◽  
Dimitrios Doumpiotis

Background: Basal cell carcinomas are malignant slow-growing neoplasms of the epidermal layer of the skin. They are the most common form of skin cancer, accounting for 80% of non-melanoma skin cancers. Metastasis is rare with an incidence rate of 0.0028 to 0.55%. We report a case of an 83 year old male presenting with basal cell carcinoma (BCC) of the right cheek. The tumour was completely excised with close margins. The patient was closely monitored clinically and on follow-up, a mass in the region of the right parotid was identified. Excision of the tail of the right parotid identified a tumour with similar subtype to the primary tumour excised from the cheek confirming diagnosis of metastatic BCC. Methods: A literature search was carried out inclusive of the terms identify existing data and guidelines to determine best evidence based practice. Discussion: Literature search identified aetiology of BCCs and methods of diagnosis and treatment. The search also highlighted an incidence rate of 0.0028 to 0.55% and complications associated with metastasis. The patient underwent a course of radiotherapy as surgery in this case was contraindicated due to history of excision of the parotid tail. Risk factors for developing BCCs include intermittent sun exposure, ionising radiation, genetic predisposition and immunosuppression. Metastases occurs via the lymphatic system or haematogenously. Surgery is the main form of treatment and aims to be curative.


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