scholarly journals Clinical and histological challenge in the differential diagnosis of diffuse alopecia: female androgenetic alopecia, telogen effluvium and alopecia areata - part II

2012 ◽  
Vol 87 (6) ◽  
pp. 884-890 ◽  
Author(s):  
Betina Werner ◽  
Fabiane Mulinari-Brenner

Diffuse alopecia is mainly caused by telogen effluvium, diffuse androgenetic alopecia (femalepattern hair loss) and diffuse alopecia areata. Differential diagnosis between the three disorders may be difficult in several occasions. In this second part of our study, chronic telogen effluvium and diffuse alopecia areata are discussed in detail, including clinical, dermoscopic and histological aspects. A flowchart presents a practical and objective differential diagnostic approach to diffuse alopecia.

2013 ◽  
Author(s):  
James Q Del Rosso

A basic knowledge of the hair growth cycle is needed to evaluate disorders of hair growth. This chapter presents a broad overview of the physiology and evaluation of hair growth, as well as discussions of specific types of alopecia. The epidemiology, pathogenesis, diagnosis, and treatment of androgenetic alopecia, the most common type of nonscarring hair loss, are covered. Diffuse hair shedding is generalized hair loss over the entire scalp. Diagnosis and treatment of telogen effluvium, anagen arrest (anagen effluvium), and other causes of diffuse hair shedding are covered in detail. Alopecia areata, typically characterized by patchy hair loss; cicatricial alopecia, which results from permanent scarring of the hair follicles; and miscellaneous causes of hair loss are also discussed. Tables list the causes of diffuse and cicatricial alopecia, telogen effluvium, and miscellaneous chemicals and categories of drugs that can cause alopecia, as well as miscellaneous causes of hair loss. Included is an algorithm outlining the approach to diagnosing nonscarring alopecia, as well as a variety of clinical photographs. This review contains 9 highly rendered figures, 6 tables, and 42 references.


2021 ◽  
pp. 1-4
Author(s):  
Luis E. Sánchez-Dueñas ◽  
Leslie E. Rocha-Méndez ◽  
Lidia Rudnicka

Trichotillomania is the most frequent reported cause of self-inflicted hair disorders, within which are included trichoteiromania, trichotemnomania, and trichocryptomania, also known as trichorrexomania. These conditions are commonly described in the context of psychiatric disorders. Nevertheless, there exists reports in otherwise healthy patients that suffer a form of no cicatricial alopecia, such as alopecia areata. We communicate 3 cases of male androgenetic alopecia with patterned miniaturization that coexisted with trichoscopic findings of trichoteiromania. The presence of brush-like ends or broom hairs is a highly suggestive feature of this entity. To the best of our knowledge, this association was not previously reported in the medical literature. The possibility of self-induced hair loss should be kept in mind during every follow-up visit in all types of alopecia, remembering that hair loss itself is already a distressing condition.


2019 ◽  
pp. 272-277 ◽  
Author(s):  
Aurora Alessandrini ◽  
Michela Starace ◽  
Francesca Bruni ◽  
Nicolò Brandi ◽  
Carlotta Baraldi ◽  
...  

Background: Alopecia areata is a nonscarring hair loss that usually causes round patches of baldness, but alopecia areata incognita (AAI) and diffuse alopecia areata (DAA) can cause a diffuse and acute pattern of hair loss. Objective: To analyze the clinical, trichoscopic, histological, and therapeutic features of AAI and DAA. Methods: The study was designed to include data of patients with histological diagnosis of AAI and DAA enrolled in our Hair Disease Outpatient Consultations. Results: DAA had a greater involvement of the parietal and anterior-temporal regions, while AAI manifested itself mainly in the occipital-parietal regions. The most frequent pattern was empty yellow dots, yellow dots with vellus hairs, and small hair in regrowth, but the presence of pigtail hair was found almost exclusively in those with AAI. In cases of DDA, the finding of dystrophic hair and black dots was more frequent. The most frequent trichoscopic sign in both diseases was the presence of empty yellow dots, which, however, were described in a higher percentage in cases of DAA. The diseases have a benign course and are responsive to topical steroid therapy. Conclusions: Trichoscopy is very important for the differential diagnosis between the 2 diseases and to select the best site for biopsy. In the presence of diffuse hair thinning, these entities must be considered.


2018 ◽  
Vol 14 (2) ◽  
pp. 116-120
Author(s):  
Manish Pradhan ◽  
Dipa Rai ◽  
Sagar Paudel

 ABSTRACTIntroduction: Total body iron store is an integral factor in the development of hair follicle. Numerous studies have been done seeking for the relationship between body iron store and various forms of chronic diffuse hair loss, with relatively contradictory findings in various reports in these studies. The main objective of this study is to find out if there is any association between total body iron store and various types of chronic diffuse hair loss in females in reproductive age.Materials and Methods: This is a hospital based case control study conducted in Nobel Medical College and Teaching Hospital, Biratnagar, Nepal. Sixty female patients of age group 15-50 years with chronic diffuse hair loss with equal number of age- and sex- matched controls were studied. Both of the study groups were evaluated for various parameters of iron status. Results: The mean value of serum ferritin in cases was significantly lower as compared to controls (p=0.018). Patients with alopecia areata (p=0.008) and androgenetic alopecia (p=0.021) had significantly lower serum ferritin, whereas there was no statistically significant difference in telogen effluvium and controls (p=0.857).The mean value of hemoglobin, hematocrit and mean corpuscular hemoglobin was found to be significantly lower in alopecia areata and androgenetic alopecia. However, there was no statistically significant difference in RBC indices of patients of telogen effluvium and controls.Conclusion: Diffuse chronic hair loss shows definite association with serum ferritin and various RBC indices in female of reproductive age group. Alopecia areata and androgenetic alopecia show major association with total body iron stores. Keywords: alopecia areata; androgenetic alopecia; serum ferritin; telogen effluvium.    


2020 ◽  
Vol 19 (6) ◽  
pp. 509-513
Author(s):  
Aida G. Gadzhigoroeva

Alopecia areata is one of the most common forms of hair loss in children. Meantime, its clinical picture is similar to trichotillomania, thus, it leads to incorrect diagnosis and management. The article provides major differential diagnosis signs for these related forms of alopecia and describes in details trichoscopic features of alopecia areata and trichotillomania.


2016 ◽  
Vol 19 (6) ◽  
pp. 359-364
Author(s):  
A. M Baltabaev ◽  
V. P Tkachev ◽  
M. K Baltabaev

Alopecia areata is a poliethiologic immune mediated condition, associated with lesion of the hair follicles, leading to disruption of growing cycle and subsequent hair loss. Taking into account the different age of patients and repeated recurrence despite of the therapy, as well as changes in the appearance of the individual affecting psychosocial status, patchy hair loss refers to the category of socially important disorders. The introduction of computer technologies facilitated diagnostic approaches through developing of specific criteria for the diagnosis of alopecia areata, which improved its differentiation with similar dermatological conditions. This publication intended to review and analyze of clinical cases of several dermatological disorders which remind clinics of different forms of alopecia areata. The importance of trichoscopy was shown to provide differential diagnosis in various hair-loss conditions to evaluate morphometric hair and skin characteristics.


Author(s):  
Ashish Dalal ◽  
Ajay Kumar ◽  
Ritambhara Lohan ◽  
Muskaan Ahlawat

<p class="abstract">A proportion of cases of diffuse hair loss over the scalp mimicking telogen effluvium or androgenetic alopecia are found to have alopecia areata incognita (AAI) on dermascopic examination and histopathology. AAI has commonly been reported in middle aged women who present with a sudden increase in hair shedding with diffuse alopecia developing after several months. Though the typical glabrous patches of hair loss observed in classical alopecia areata are absent, the abrupt and intense hair loss with a positive hair pull test is suggestive of AAI. There are few reports of AAI occurring in children. We are reporting a case of AAI in a 6-year old child. </p>


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