scholarly journals Seroprevalence of Helicobacter pylori infection among children of low socioeconomic level in São Paulo

2010 ◽  
Vol 128 (4) ◽  
pp. 187-191 ◽  
Author(s):  
Aurea Cristina Portorreal Miranda ◽  
Rodrigo Strehl Machado ◽  
Edina Mariko Koga da Silva ◽  
Elisabete Kawakami
Keyword(s):  
Helicobacter Pylori ◽  
Cross Sectional Study ◽  
Sao Paulo ◽  
Helicobacter Pylori Infection ◽  
Socioeconomic Level ◽  
São Paulo ◽  
Sectional Study ◽  
Cross Sectional ◽  
Low Socioeconomic ◽  
H Pylori

CONTEXT AND OBJECTIVE: Helicobacter pylori infection is mainly acquired during childhood, and is associated with significant morbidity in adults. The aim here was to evaluate the seroprevalence and risk factors of H. pylori infection among children of low socioeconomic level attended at a public hospital in São Paulo, Brazil. DESIGN AND SETTING: Cross-sectional study, among patients attended at an outpatient clinic. METHODS: 326 children were evaluated (150 boys and 176 girls; mean age 6.82 ± 4.07 years) in a cross-sectional study. Patients with chronic diseases or previous H. pylori treatment, and those whose participation was not permitted by the adult responsible for the child, were excluded. The adults answered a demographic questionnaire and blood samples were collected. The serological test used was Cobas Core II, a second-generation test. Titers > 5 U/ml were considered positive. RESULTS: H. pylori infection was diagnosed in 116 children (35.6%). Infected children were older than uninfected children (7.77 ± 4.08 years versus 5.59 ± 3.86 years; p < 0.0001). The seroprevalence increased from 20.8% among children aged two to four years, to 58.3% among those older than 12 years. There were no significant relationships between seropositivity and gender, color, breastfeeding, number of people in the home, number of rooms, bed sharing, living in a shantytown, maternal educational level, family income or nutritional status. In multivariate analysis, the only variable significantly associated with H. pylori seropositivity was age. CONCLUSION: Infection had intermediate prevalence in the study population, and age was associated with higher prevalence.

scholarly journals Prevalência de infecção por Helicobacter pylori em uma comunidade indígena em São Paulo e fatores associados: estudo transversal

2017 ◽  
Vol 135 (2) ◽  
pp. 140-145 ◽  
Author(s):  
Juliana Rejane da Silva Roque ◽  
Rodrigo Strehl Machado ◽  
Douglas Rodrigues ◽  
Patrícia Rech ◽  
Elisabete Kawakami
Keyword(s):  
Helicobacter Pylori ◽  
Demographic Data ◽  
Cross Sectional Study ◽  
Sao Paulo ◽  
Helicobacter Pylori Infection ◽  
São Paulo ◽  
Cross Sectional ◽  
Intestinal Parasitosis ◽  
Previous Hospitalization ◽  
13C Urea Breath Test

ABSTRACT CONTEXT AND OBJECTIVE: The prevalence of Helicobacter pylori infection is unevenly distributed among different populations. The aim here was to evaluate the factors associated with Helicobacter pylori infection among children up to five years of age living in a high-risk community. DESIGN AND SETTING: Cross-sectional study in an indigenous community of Guarani Mbya ethnicity, Tekoa Ytu and Tekoa Pyau villages, Jaraguá district, city of São Paulo (SP), Brazil. METHODS: 74 children aged 0.4 to 4.9 years (mean 2.9 ± 1.3 years; median 3.1), and 145 family members (86 siblings, 43 mothers and 16 fathers) were evaluated for Helicobacter pylori infection using the validated 13C-urea breath test. Clinical and demographic data were collected. RESULTS: The prevalence was 8.3% among children aged 1-2 years and reached 64.3% among those aged 4-5 years (P = 0.018; overall 31.1%). The prevalence was 76.7% among siblings and 89.8% among parents. There was a negative association with previous use of antibiotics in multivariate analysis adjusted for age (odds ratio, OR: 0.07; 95% confidence interval, CI: 0.01 to 0.66; P = 0.02). The prevalence was higher among males (OR: 1.55), and was associated with maternal infection (OR: 1.81), infection of both parents (OR: 1.5), vomiting (OR: 1.28), intestinal parasitosis (OR: 2.25), previous hospitalization (OR: 0.69) and breastfeeding (OR: 1.87). CONCLUSIONS: The prevalence was high among subjects older than three years of age, thus suggesting that the incidence of infection was higher over the first three years of life. Previous use of antibiotics was inversely associated with current Helicobacter pylori infection.

scholarly journals The Association Between Helicobacter Pylori Infection and Erosive Gastroesophageal Reflux Disease; a Cross-Sectional Study

2021 ◽  
Author(s):  
Ramin Niknam ◽  
Kamran Bagheri Lankarani ◽  
Mohsen Moghadami ◽  
Seyed Alireza Taghavi ◽  
Leila Zahiri ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Gastroesophageal Reflux Disease ◽  
Gastroesophageal Reflux ◽  
Hiatus Hernia ◽  
Reflux Disease ◽  
Cross Sectional Study ◽  
Helicobacter Pylori Infection ◽  
Sectional Study ◽  
Cross Sectional ◽  
H Pylori

Abstract Background The association between H. pylori (Helicobacter pylori) infection and gastroesophageal reflux disease (GERD) is a complex and confusing subject, so we designed this study. Method In a cross-sectional study, all patients referred for endoscopy due to dyspepsia were enrolled. The diagnosis of erosive GERD was made by endoscopy. Patients with normal esophagus were selected as comparison group. Random gastric biopsies were taken from all participants to diagnose H. pylori infection. Result In total, 1916 patients were included in this study, of whom 45.6% had GERD. The mean age (SD) was 42.95 (16.32). Overall, 1442 (75.3%) patients were positive for H. pylori infection. The frequency of H. pylori infection in mild GERD patients was higher than the severe GERD, but this difference was not significant (P=0.214). Except for sociodemographic status (P < 0.001), other variables including gender, age, ethnicity, body mass index (BMI), smoking, and presence of hiatus hernia in patients had no significant association with the frequency of H. pylori infection. According to Robust Poisson regression models analysis, the association of H. pylori (PR 1.026;95%CI 0.990-1.064; P=0.158) and sociodemographic status were not significantly different between the two groups. But smoking, increased BMI, older age, presence of hiatus hernia, and peptic ulcer diseases were significantly associated with GERD compared with the non-GERD group. Conclusion In our results, there was no association between H. pylori infection and erosive GERD. Further studies are recommended, especially considering the effects of pathophysiological and other confounding factors on H. pylori and GERD.

scholarly journals A descriptive cross-sectional study of helicobacter pylori infection in non-ulcer dyspepsia patients in a tertiary care teaching hospital In the Eastern part of Nepal

2016 ◽  
Vol 5 (2) ◽  
pp. 10-16
Author(s):  
Rishab Shrestha ◽  
Gaurav Chhetri ◽  
Arbind Deo ◽  
Rabindra Nath Das
Keyword(s):  
Helicobacter Pylori ◽  
Teaching Hospital ◽  
Tertiary Care ◽  
Cross Sectional Study ◽  
Helicobacter Pylori Infection ◽  
P Value ◽  
Sectional Study ◽  
Cross Sectional ◽  
Non Ulcer Dyspepsia ◽  
H Pylori

Background In Gastroenterology practice, worldwide, the most common cause of dyspepsia is functional. Functional or non-ulcer dyspepsia is established by gastroduodenoscopy which rules out structural disorders in dyspeptic patients. Helicobacter pylori, a gram-negative bacterium in gastric mucosa is associated with non-ulcer dyspepsia, chronic gastritis, gastriculcer and cancer. Worldwide prevalence of Helicobacter pylori infection is higher but its association with non-ulcer dyspepsia is less clear.Material and Methods The aim of this study was to see the prevalence of H. pylori infection in non-ulcer dyspepsia. A cross-sectional study of 340 patients presented at Nobel Teaching Hospital in one year with dyspeptic symptoms underwent clerking, physical examination, gastroduodenoscopy and RUT. Symptomatic patients without any structural lesions were designated as functional dyspepsia. RUT when turned red indicated positive for H. pylori infection.Result Out of 340 patients, 180 (52.9%) were female and 160(47.1%) were male. Mean age of male and female patients was 35.88 ± 11.8 and 38.11 ± 11.7 respectively. Amongst all participants 150 (44.11%) were housewives and 69(20.3%) were students. Endoscopic findings showed gastritis 205(60.29%) and duodenitis 15(4.42%). RUT was found positive in 62% of gastritis and 86.7% of duodenitis patients (p value=0.001).Conclusion High prevalence of H pylori infection in present study may be one of the causative factors in producing symptomatic non-ulcer dyspepsia. Hence, early detection and complete eradication of H.pylori infection is mandatory. It will reduce usage of PPIs and also improve quality of life.Journal of Nobel Medical College Vol.5(2) 2016; 10-16

scholarly journals PREVALENCE OF HELICOBACTER PYLORI TEN YEARS AGO COMPARED TO THE CURRENT PREVALENCE IN PATIENTS UNDERGOING UPPER ENDOSCOPY

2016 ◽  
Vol 29 (3) ◽  
pp. 151-154 ◽  
Author(s):  
Sandra FRUGIS ◽  
Nicolau Gregori CZECZKO ◽  
Osvaldo MALAFAIA ◽  
Artur Adolfo PARADA ◽  
Paula Bechara POLETTI ◽  
...  
Keyword(s):  
Helicobacter Pylori ◽  
Cross Sectional Study ◽  
World Population ◽  
Upper Endoscopy ◽  
Sectional Study ◽  
Cross Sectional ◽  
Current Prevalence ◽  
Number Of Patients ◽  
Two Samples ◽  
H Pylori

ABSTRACT Background: Helicobacter pylori has been extensively studied since 1982 it is estimated that 50% of the world population is affected. The literature lacks studies that show the change of its prevalence in the same population over time. Aim: To compare the prevalence of H. pylori in 10 years interval in a population that was submitted to upper endoscopy in the same endoscopy service. Method: Observational, retrospective and cross-sectional study comparing the prevalence of H. pylori in two samples with 10 years apart (2004 and 2014) who underwent endoscopy with biopsy and urease. Patients were studied in three consecutive months of 2004, compared to three consecutive months of 2014. The total number of patients was 2536, and 1406 in 2004 and 1130 in 2014. Results: There were positive for H. pylori in 17 % of the sample as a whole. There was a significant decrease in the prevalence from 19.3% in 2004 to 14.1% in 2014 (p<0.005). Conclusion: There was a 5.2% reduction in the prevalence of H. pylori comparing two periods of three consecutive months with 10 years apart in two equivalent population samples.

Sign in / Sign up

Export Citation Format

Share Document