scholarly journals The effect of treatment with melatonin upon the ultrastructure of the mouse pineal gland: a quantitative study

2001 ◽  
Vol 61 (4) ◽  
pp. 679-684 ◽  
Author(s):  
G. M. REDINS ◽  
C. A. REDINS ◽  
J. C. NOVAES
Keyword(s):  
Electron Microscopy ◽  
Transmission Electron Microscopy ◽  
Pineal Gland ◽  
Quantitative Study ◽  
Subcutaneous Injection ◽  
Secretory Activity ◽  
Secretory Process ◽  
Volumetric Density ◽  
Transmission Electron ◽  
Effect Of Treatment

In order to evaluate melatonin implication in the regulating of its own secretory process by pinealocytes, we used morphometric techniques for transmission electron microscopy. In mice treated with 100 mg of melatonin (N-acetyl-5-methoxy-tryptamine) by daily subcutaneous injection, we observed a decrease in number and volumetric density of lysosomes. Our results showed that melatonin influences the secretory activity of pinealocytes and participates in a complex secretory regulating mechanism.

scholarly journals Morphological structure of rat epiphysis exposed to electromagnetic radiation from communication devices

2019 ◽  
Vol 95 (10) ◽  
pp. 977-979
Author(s):  
Svetlana G. Yashchenko ◽  
S. Yu. Rybalko
Keyword(s):  
Electron Microscopy ◽  
Transmission Electron Microscopy ◽  
Pineal Gland ◽  
Electromagnetic Radiation ◽  
Mobile Phones ◽  
Morphological Changes ◽  
The Body ◽  
Transmission Electron ◽  
Communication Devices ◽  
Rat Pineal Gland

Pineal gland is one of the most important components of homeostasis - the supporting system of the body. It participates in the launch of stress responses, restriction of their development, prevention of adverse effects on the body. There was proved an impact of electromagnetic radiation on the epiphysis. However, morphological changes in the epiphysis under exposure to electromagnetic radiation of modern communication devices are studied not sufficiently. For the time present the population is daily exposed to electromagnetic radiation, including local irradiation on the brain. These date determined the task of this research - the study of the structure of rat pineal gland under the exposure to electromagnetic radiation from personal computers and mobile phones. These date determined the task of this research - the study of the structure of rat pineal gland under the exposure to electromagnetic radiation from personal computers and mobile phones. Performed transmission electron microscopy revealed signs of degeneration of dark and light pinealocytes. These signs were manifested in the development of a complex of general and specific morphological changes. There was revealed the appearance of signs of aging and depletion transmission electron microscopy both in light and dark pinealocytes. These signs were manifested in the accumulation of lipofuscin granules and electron-dense "brain sand", the disappearance of nucleoli, cytoplasm vacuolization and mitochondrial cristae enlightenment.

scholarly journals Pineal gland calcification under hypoxic conditions

2019 ◽  
pp. S405-S413
Author(s):  
M. Kopáni ◽  
B. Vraníková ◽  
D. Kosnáč ◽  
M. Zeman ◽  
V. Šišovský ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Transmission Electron Microscopy ◽  
Chemical Composition ◽  
Pineal Gland ◽  
Fibrous Material ◽  
Prenatal Hypoxia ◽  
Hypoxic Conditions ◽  
Hypoxia Group ◽  
Transmission Electron ◽  
The Brain

The pineal gland (glandula pinealis) is neuroendocrine gland located at the epithalamus of the brain secreting melatonin. The aim of this study was to explore effects of prenatal hypoxia in rats at the age of 33 weeks on the occurrence of pineal gland calcification. Distribution and chemical composition of calcerous material by light, scanning and transmission electron microscopy was investigated. Melatonin concentrations in blood plasma by direct radioimmunoassay were measured. Rats were exposed to prenatal hypoxia for 12 h at day 20 of development and second group to prenatal hypoxia for 2x8 h at days 19 and 20 of development. Vacuoles of intracellular edema in the pineal samples after 12 h hypoxia were found. Their size ranges up to 30 µm. Some of them were filled with the flocculent and fibrous material. Samples of pineal glands after 2 x 8 h hypoxia revealed the pericellular edema of pinealocytes. The amount of calcium rich particles in 2 x 8 h hypoxia group was lower than in 12 h hypoxia group. Plasma melatonin levels did not differ between control and both hypoxia groups. We concluded that calcification is a process induced by osteoblasts and osteocytes with melatonin as a promotor and it is favored under hypoxic conditions.

A transmission electron microscopy quantitative study of the growth kinetics of H platelets in Si

2000 ◽  
Vol 76 (7) ◽  
pp. 852-854 ◽  
Author(s):  
J. Grisolia ◽  
G. Ben Assayag ◽  
A. Claverie ◽  
B. Aspar ◽  
C. Lagahe ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Transmission Electron Microscopy ◽  
Quantitative Study ◽  
Growth Kinetics ◽  
Transmission Electron ◽  
Kinetics Of
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