The evaluation of surgical reconstruction for intermittent claudication by the Walking Impairment Questionnaire

BACKGROUND: No standards reflecting the quality of life (QOL) and activity of daily living (ADL) in postoperative clinical course have been validated in the area of vascular disease. The Walking Impairment Questionnaire (WIQ) is a disease-specific questionnaire that evaluates patients with intermittent claudication due to arteriosclerosis obliterans (ASO). The WIQ uses four subscales: pain severity, walking distance, walking speed, and stair climbing while walking. OBJECTIVE: To evaluate the correlation between postoperative arterial blood flow and the Japanese edition of the WIQ. METHODS: Thirty-one patients (47 limbs) with intermittent claudication who had been subjected to lower limb surgical arterial reconstruction were assessed by WIQ, and compared with Ankle-Brachial Pressure Index (ABPI) and angiography. RESULTS: A significant increase in the WIQ score was identified in walking pain (26 versus 89.5, p<0.001), walking distance (13.1 versus 83.3, p<0.001), walking speed (10 versus 46, p<0.001), and stair climbing (6.2 versus 79, p<0.001). The correlation coefficient between the increase in postoperative ABPI and the WIQ score was R²=0.1889, which shows weak correlation. The correlation between blood flow obstruction due to the postoperative bypass that was scored by angiography and WIQ score was R²=0.3894, which shows moderate correlation. CONCLUSION: An improvement in the Japanese edition of the WIQ score was correlated not only with the patients' QOL after bypass revascularization but also with the rate of increase of postoperative ABPI and image findings, such as the postoperative angiography.

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Intermittent claudication - the meaning of pharmacological and non-pharmacological therapy in chronic treatment

Medycyna Faktów ◽

10.24292/01.mf.0321.4 ◽

2021 ◽

Vol 14 (3) ◽

pp. 240-243

Author(s):

Marta Wolska ◽

Pamela Czajka ◽

Marek Postuła

Keyword(s):

Intermittent Claudication ◽

Conservative Therapy ◽

Ankle Brachial Index ◽

Cardiovascular Complications ◽

Pharmacological Therapy ◽

Arterial Blood Flow ◽

Diagnostic Process ◽

Arterial Blood ◽

Artery Disease

Intermittent claudication is a typical sign of peripheral vascular disease, which results from limited arterial blood flow due to atherosclerosis, appears during exercises and is relieved after a short break. Intermittent claudication often presents as a pain in the calf muscle after walking a particular distance. Physical examination, detailed interview and ankle–brachial index are key elements of the diagnostic process, which allows for diagnosis of peripheral artery disease. The treatment is dependent on multiple factors, including the dynamics of the disease and coexisting diseases. The aim of the treatment of patients with intermittent claudication is reducing the risk of cardiovascular complications and improving the quality of life. The treatment is based on a conservative therapy, especially march training. The pharmacological treatment is limited to a few medications, which are rarely used. In the advanced stage of the disease the most appropriate option seems surgery.

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Changes in Umbilical Arterial Blood Flow by an Intraamniotic Distilled Water Infusion

Yearbook of Obstetrics Gynecology and Women s Health ◽

10.1016/s1090-798x(08)70024-9 ◽

2007 ◽

Vol 2007 ◽

pp. 30-31

Author(s):

S.H. Ural

Keyword(s):

Blood Flow ◽

Arterial Blood Flow ◽

Distilled Water ◽

Arterial Blood ◽

Water Infusion

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Ventilatory threshold is related to walking tolerance in patients with intermittent claudication

VASA ◽

10.1024/0301-1526/a000203 ◽

2012 ◽

Vol 41 (4) ◽

pp. 275-281 ◽

Cited By ~ 3

Author(s):

da Rocha Chehuen ◽

G. Cucato ◽

P. dos Anjos Souza Barbosa ◽

A. R. Costa ◽

M. Ritti-Dias ◽

...

Keyword(s):

Blood Flow ◽

Oxygen Uptake ◽

Intermittent Claudication ◽

Lower Limb ◽

Ventilatory Threshold ◽

Reactive Hyperemia ◽

Ankle Brachial Index ◽

Metabolic Parameters ◽

Walking Distance ◽

The Relationship

Background: This study assessed the relationship between lower limb hemodynamics and metabolic parameters with walking tolerance in patients with intermittent claudication (IC). Patients and methods: Resting ankle-brachial index (ABI), baseline blood flow (BF), BF response to reactive hyperemia (BFRH), oxygen uptake (VO2), initial claudication distance (ICD) and total walking distance (TWD) were measured in 28 IC patients. Pearson and Spearman correlations were calculated. Results: ABI, baseline BF and BF response to RH did not correlate with ICD or TWD. VO2 at first ventilatory threshold and VO2peak were significantly and positively correlated with ICD (r = 0.41 and 0.54, respectively) and TWD (r = 0.65 and 0.71, respectively). Conclusions: VO2peak and VO2 at first ventilatory threshold, but not ABI, baseline BF and BFHR were associated with walking tolerance in IC patients. These results suggest that VO2 at first ventilatory threshold may be useful to evaluate walking tolerance and improvements in IC patients.

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Impact of Pre Transplant Transarterial Chemoembolization on Hepatic Arterial Blood Flow and Outcomes in Liver Transplantation

10.26226/morressier.58eb975dd462b80290b50084 ◽

2017 ◽

Author(s):

Siddharth Jain

Keyword(s):

Liver Transplantation ◽

Blood Flow ◽

Transarterial Chemoembolization ◽

Arterial Blood Flow ◽

Hepatic Arterial Blood Flow ◽

Arterial Blood

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Modeling Elastic Walls in Lattice Boltzmann Simulations of Arterial Blood Flow

SNE Simulation Notes Europe ◽

10.11128/sne.23.tn.10189 ◽

2013 ◽

Vol 23 (2) ◽

Author(s):

Xenia Descovich ◽

Giuseppe Pontrelli ◽

Sauro Succi ◽

Simone Melchionna ◽

Manfred Bammer

Keyword(s):

Blood Flow ◽

Lattice Boltzmann ◽

Arterial Blood Flow ◽

Arterial Blood ◽

Lattice Boltzmann Simulations ◽

Elastic Walls

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Sustained Inflation Reduces Pulmonary Blood Flow during Resuscitation with an Intact Cord

Children ◽

10.3390/children8050353 ◽

2021 ◽

Vol 8 (5) ◽

pp. 353

Author(s):

Jayasree Nair ◽

Lauren Davidson ◽

Sylvia Gugino ◽

Carmon Koenigsknecht ◽

Justin Helman ◽

...

Keyword(s):

Blood Flow ◽

Perinatal Asphyxia ◽

Arterial Blood Flow ◽

Positive Pressure ◽

Optimal Timing ◽

Delayed Cord Clamping ◽

Arterial Blood ◽

Cord Clamping ◽

Sustained Inflation ◽

Near Term

The optimal timing of cord clamping in asphyxia is not known. Our aims were to determine the effect of ventilation (sustained inflation–SI vs. positive pressure ventilation–V) with early (ECC) or delayed cord clamping (DCC) in asphyxiated near-term lambs. We hypothesized that SI with DCC improves gas exchange and hemodynamics in near-term lambs with asphyxial bradycardia. A total of 28 lambs were asphyxiated to a mean blood pressure of 22 mmHg. Lambs were randomized based on the timing of cord clamping (ECC—immediate, DCC—60 s) and mode of initial ventilation into five groups: ECC + V, ECC + SI, DCC, DCC + V and DCC + SI. The magnitude of placental transfusion was assessed using biotinylated RBC. Though an asphyxial bradycardia model, 2–3 lambs in each group were arrested. There was no difference in primary outcomes, the time to reach baseline carotid blood flow (CBF), HR ≥ 100 bpm or MBP ≥ 40 mmHg. SI reduced pulmonary (PBF) and umbilical venous (UV) blood flow without affecting CBF or umbilical arterial blood flow. A significant reduction in PBF with SI persisted for a few minutes after birth. In our model of perinatal asphyxia, an initial SI breath increased airway pressure, and reduced PBF and UV return with an intact cord. Further clinical studies evaluating the timing of cord clamping and ventilation strategy in asphyxiated infants are warranted.

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