scholarly journals Livedoid vasculopathy: fast involution after anticoagulant and hyperbaric oxygen therapy

2011 ◽  
Vol 9 (2) ◽  
pp. 212-215 ◽  
Author(s):  
Patricia Weinschenker Bollmann ◽  
Andréa Kazumi Shimada ◽  
Nilceo Schwery Michalany ◽  
Ana Rita de Araújo Burgos Manhani ◽  
Auro del Giglio

The livedoid vasculopathy is a rare condition characterized by the presence of recurrent painful ulcers in distal extremities of lower limbs. Histologically there is thickness of dermal vessels, occlusion of its light by fibrin thrombi associated with minimal inflammatory infiltrate. It might occur as an isolated condition or be associated with an underlying systemic disease, including coagulation and collagen disorders, or neoplasms. Because it is a rare disease there is no consensus for its treatment. We report a case of a 41-year-old man with painful ulcers in the lower extremities. We did not find any associated diseases. The lesions improved dramatically after treatment with anticoagulant and hyperbaric therapy. We concluded that anticoagulation associated with hyperbaric oxygenation may be benefit for the treatment of patients with livedoid vasculopathy. However, further studies should be done with a larger population to confirm our results.

2020 ◽  
Vol 70 (1) ◽  
pp. 43-46
Author(s):  
Władysław Wolański

AbstractThe aim of the study was to determine the effect of the application of hyperbaric oxygen therapy on the course of an infection with group A type T-3 hemolytic β streptococcus. Experiments were carried out on Porton white mice and in vitro blood plates. General and local infections with streptococci were induced in animals. The infected animals were treated with hyperbaric oxygenation. The lethal effect of infection was significantly inhibited using hyperbaric oxygenation on the first and second day following the infection.


2016 ◽  
Vol 56 (3) ◽  
pp. 25-32
Author(s):  
Małgorzata Skiba ◽  
Agnieszka Pedrycz

Abstract In this publication, we adduce examples of the use of hyperbaric oxygen therapy in urinary tract diseases. Hyperbaric oxygen therapy has been proved to have a positive influence on the kidneys of animals with diabetes, sepsis or undergoing chemotherapy. In the literature, we can also find many examples of the use of hyperbaric therapy with good clinical outcomes in human patients with prostatic hypertrophy, pyelonephritis, and hemorrhagic cystitis. The first trials of this kind of treatment of urinary tract diseases were started at the end of the twentieth century. In spite of the promising results, and numerous reports on the effectiveness of this non-invasive method of treatment, it is not currently used on a regular basis. Because many factors such as time, multiple applications, the parameters used in the hyperbaric chamber as well as the medications taken by the patient affect the quality of the result, further studies are needed to make hyperbaric therapy more suitable and safer for each patient.


2015 ◽  
Vol 28 (5) ◽  
pp. 619 ◽  
Author(s):  
Isabel Rosa ◽  
Francisco Guerreiro

<p><strong>Introduction:</strong> Fournier’s gangrene is a serious necrotizing infection that can be fatal if not promptly attended. Treatment for this condition consists of a combination of surgical debridement, antibiotherapy and supportive care. Hyperbaric oxygen therapy is used as an adjuvant for the optimization of infected tissue oxygenation and for its bactericidal and bacteriostatic effects.<br /><strong>Material and Methods:</strong> The data presented in this study encompass a period of 25 years of clinical records of patients with Fournier’s gangrene that had been treated at our center with hyperbaric oxygen therapy.<br /><strong>Results:</strong> A total of 34 patients were treated. The vast majority of patients were males (94.1%) with a mean age of 53.7 years. Urinary tract was the most frequent source of infection and diabetes was most common comorbidity seen in patients. Mortality rate was 20.8%.<br /><strong>Discussion:</strong> The most common observed comorbidity was diabetes, suggesting diabetes as one predisposing factor. The majority of deceased patients had diabetes, although no significant correlation between diabetes and death was found. The area of residence of patients may affect patients’ referral to these facilities.<br /><strong>Conclusions:</strong> Although Fournier’s gangrene is a rare condition, it is nevertheless a fatal illness, namely in patients with comorbidities like diabetes. Hyperbaric oxygen therapy is recommended as an adjuvant to conventional therapy and should be considered whenever available. To further assess the role of hyperbaric oxygen therapy, in the treatment of this condition, additional studies should be carried out.</p>


2021 ◽  
Vol 27 (2) ◽  
pp. 3772-3777
Author(s):  
Krasimira Tsankova ◽  
◽  
Mila Dimitrova ◽  

Background: Hyperbaric oxygenation (HBO) is a treatment in which a patient breathes near 100% oxygen within a chamber at a pressure greater than one atmosphere absolute (ATA). The development of hyperbaric medicine is continuous and associated with the history of underwater activities, the development of physical laws and physiological mechanisms of breathing. Purpose: The aim of this article is to present the development of hyperbaric oxygenation internationally and nationally. Materials and Methods: We have conducted a literature review of the published works on hyperbaric oxygen therapy (HBOT) during the last 100 years. Our survey includes scientific reports and books in English and Bulgarian. Results: Three main periods of the historical development of HBOT can be defined. In the past, HBO did not have much scientific support but is extensively used in the field of medicine. We observed an increase in scientific interest in HBO during the last two decades both in our country and worldwide. The majority of the reviewed articles contained information about different aspects of HBO as clinical uses, effects, risks. HBOT has been used as a primary and adjuvant treatment for a variety of diseases for nearly 50 years in Bulgaria. The main areas of application and researches of hyperbaric oxygen therapy include diving diseases, intoxications, traumatic injuries, soft tissue infections, diabetic foot, hearing loss, some neurological disorders, etc. Conclusion: Over the past decades, hyperbaric oxygen therapy has grown rapidly worldwide in accordance with evidence-based medicine methods, and future developments to expand the knowledge are perspective.


2015 ◽  
Vol 60 (5) ◽  
pp. 524 ◽  
Author(s):  
Biju Vasudevan ◽  
Jandhyala Sridhar ◽  
Rajeev Deo ◽  
CS Mohanty ◽  
Rahul Ray ◽  
...  

2006 ◽  
Vol 6 (2) ◽  
pp. 21-24 ◽  
Author(s):  
Ana Mitrović ◽  
Branka Nikolić ◽  
Svetlana Dragojević ◽  
Predrag Brkić ◽  
Aleksandar Ljubić ◽  
...  

Endometrial sonographic and color doppler features can be used to predict the occurrence of pregnancy in natural or stimulated cycles. Implantation will usually only take place if the endometrium has reach a certain stage of vascularisation and development. The aim of this study was to evaluate endometrial development -- endometrial thickness and reflectivity , subendometrial, endometrial and uterine perfusion, after hyperbaric oxygenation, using transvaginal color doppler. During a three years period 32 women with unexplained infertility were entered into a randomised study. The patients were treated in multiplaced HAUX chamber at pressure of 2.3 ATA during 70 minutes, 7 days consecutively beginning with day 5th of menstrual cycle. The evaluation of effects of hyperbaric oxygen therapy was carried out by transvaginal color doppler sonography which was continuously used starting from 8th day of menstrual cycle until the ovulation in the cycles when the therapy was applied , one month before and one month after the therapy. Folliculometry in the cycles when hyperbaric oxygen therapy at 2.3 ATA was applied, indicated an excellent response of endometrium. Thickness of endometrium at the time of ovulation was 11.0 +/- 2.6 mm. Desirable quality of endometrium was significantly better in the cycle when HBO therapy had been applied (p< 0.001). The doppler flowmetry of the uterine arteries indicated that the uterine blood vessel resistance was slightly higher than expected. Mapping of subendometrial blood vessels in the cycles covered by hyperbaric oxygen therapy showed the intensive capillary network of endometrium with low resistance Ri< 0.45. The oxygen used under higher pressure -- oxygen as a drug , may have an extraordinary significance for better outcome of pregnancy implantation by improving endometrial receptivity. If endometrial receptivity is conditioned by adequate vascularisation and oxygenation, then hyperbaric oxygen therapy is the treatment of choice.


2018 ◽  
Vol 6 (2) ◽  
pp. 292
Author(s):  
Pravita Dwi Ariyani ◽  
Dodi Wijaya ◽  
Ahmad Rifai

Hyperbaric oxygen therapy is a treatment method in patients with inhaling pure oxygen at pressuresgreater than normal atmospheric pressure. Patients who first followed the hyperbaric therapy willgenerally feel anxiety due to side effects of hyperbaric therapy. Orientation procedure can be used todecrease level of anxiety of patients. The purpose of this study was to analyze the effect of theorientation procedure on the level of anxiety of patients undergoing hyperbaric oxygen therapy atRumah Sakit Paru Jember. The design of study was pre experimental design with one group pretestand post test. The sampling technique was consecutive sampling involving 32 respondents. Datawere analyzed with Wilcoxon Test. The result showed a significant decrease of moderate anxiety tomild anxiety with implementation of orientation procedure (p=0.000). It can be concluded that thereis an effect of the orientation procedure on the level of anxiety of patients undergoing hyperbaricoxygen therapy at Rumah Sakit Paru Jember. The provision of adequate information and theintroduction of a hyperbaric chamber every corner of the room so that the patient is able to adapt tothe first experience, so that the necessary role of nurses in assisting the patient to provide referralsfor patients who want to undergoing hyperbaric therapy in order to follow the therapy process untilcomplete. Orientation procedure of hyperbaric therapy can be applied as one of method to decreaselevel of anxiety of patients undergoing hyperbaric oxygen therapyKeywords: orientation procedure, hyperbaric oxygen therapy, level of anxiety


2019 ◽  
pp. 1-5

Abstract Fournier syndrome is a synergistic polymicrobial infection that mainly affects the perianal, perineal and genital regions. It is a relatively rare disease with high mortality and an estimated overall incidence of 1.6/100,000 men. Diagnosis is clinical and an early detection is crucial to improve patient outcomes. Treatment is based on three pillars: initial patient stabilization, broad-spectrum antibiotic therapy and extensive surgical debridement of the entire necrotic area. Currently, hyperbaric oxygen therapy has been used as an adjunctive treatment. This study aimed to report the case of a patient with Fournier syndrome who underwent the three-pillar treatment and also hyperbaric oxygenation with a satisfactory result.


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